syn Additions to 4α-Epoxypyranosides:  Synthesis of l-Idopyranosides

The syn-selective addition of organozinc compounds to 4α-epoxypyranosides (4α-EPs), generated from methyl β-d-glucoside or aminoglucoside, provides an efficient route to pyranosides with α-l-ido configurations, including l-iduronic acid, neosamine B, and higher monosaccharide derivatives.