ol7b03941_si_001.pdf (4.34 MB)
Rhodium-Catalyzed Asymmetric Arylative Ring-Opening Reactions of Heterobicyclic Alkenes with Anilines
journal contribution
posted on 2018-02-22, 15:20 authored by Jingchao Chen, Lingling Zou, Chaoyuan Zeng, Yongyun Zhou, Baomin FanAsymmetric
arylative ring-opening reactions of heterobicyclic alkenes
with anilines have been reported for the first time. A wide range
of heterobicyclic alkenes, including azabenzonorbornadienes and oxabenzonorbornadienes,
were well tolerated in the reaction with various anilines, and they
generally delivered the corresponding chiral aryltetralin derivatives
in good to excellent enantioselectivities. The reaction is speculated
to proceed through the Friedel–Crafts reaction pathway.