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Palladium-Catalyzed Ring-Opening Reaction of Methyleneaziridines with Carboxylic Acids:  Synthesis of α-Amidoketones

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journal contribution
posted on 16.04.2004, 00:00 by Byoung Ho Oh, Itaru Nakamura, Yoshinori Yamamoto
In the presence of palladium catalysts, the reaction of methyleneaziridines 1 with carboxylic acids 2 proceeded smoothly to give the corresponding α-amidoketones 3 in good to high yields.

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