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Interaction of a Phospholipid and a Coagulating Protein: Potential Candidate for Bioelectronic Applications

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journal contribution
posted on 2022-05-17, 21:05 authored by Ripa Paul, Hritinava Banik, Meshal Alzaid, Debajyoti Bhattacharjee, Syed Arshad Hussain
In the present communication, we have investigated the interaction between a biomembrane component 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) and a coagulating protein protamine sulfate (PS) using the Langmuir–Blodgett (LB) technique. The π–A isotherm, π–t characteristics, and analysis of isotherm curves suggested that PS strongly interacted with DOPC, affecting the fluidity of the DOPC layer. Electrical characterization indicates that PS as well as the PS–DOPC film showed resistive switching behavior suitable for Write Once Read Many (WORM) memory application. Trap-controlled space charge-limited conduction (SCLC) was the key mechanism behind such observed switching. The presence of DOPC affected the SCLC process, leading to lowering of threshold voltage (VTh), which is advantageous in terms of lower power consumption.

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