ol052058u_si_001.pdf (2.28 MB)
Download file

Cyclohexenones as Michael Acceptors in the Staunton−Weinreb Annulation: A Simple Stannane Modification for the Synthesis of Polycyclic Systems

Download (2.28 MB)
journal contribution
posted on 10.11.2005, 00:00 authored by Bryan Hill, Russell Rodrigo
o-Toluate anions generated via transmetalation from the corresponding tributyl stannane underwent a Michael addition−Dieckmann condensation sequence with various cyclohexenones. This protocol provides an efficient entry into complex polycyclic systems without the use of β-alkoxy enones hitherto required for the reaction.

History