Concise Syntheses of Hyrtioreticulins C and D via a C‑4 Pictet–Spengler Reaction: Revised Signs of Specific Rotations

The first syntheses of hyrtioreticulins C and D via a Pictet–Spengler reaction at the C-4 position of the indole rings are described. The synthesis proceeds in only two steps from commercially available starting materials. In this Communication, the structures of the natural products were confirmed. Furthermore, we revise the signs of the specific rotations of hyrtioreticulins C and D.