Synthesis of γ-Benzopyranone by TfOH-Promoted Regioselective Cyclization of o-Alkynoylphenols
journal contributionposted on 02.09.2011 by Masahito Yoshida, Yuta Fujino, Takayuki Doi
Any type of content formally published in an academic journal, usually following a peer-review process.
Regioselective cyclization of o-alkynoylphenols forming γ-benzopyranones has been demonstrated. Trifluoromethanesulfonic acid (TfOH) induced 6-endo cyclization of o-alkynoylphenols without forming 5-exo cyclized benzofuranone derivatives to provide the corresponding γ-benzopyranones in high yields.