An Asymmetric Hetero-Claisen Approach to 3-Alkyl-3-aryloxindoles

The reaction of a chiral <i>N</i>-phenylnitrone derived from Garner’s aldehyde with alkylarylketenes generates 3-alkyl-3-aryloxindoles directly in excellent yields and with good to excellent levels of enantioselectivity (up to 90% ee).