GO_baits GOamounts_baits GO_preys GOamounts_preys BP_baits BPamounts_baits BP_preys BPamounts_preys MF_baits MFamounts_baits MF_preys MFamounts_preys CC_baits CCamounts_baits CC_preys CCamounts_preys protein binding 74 protein binding 1067 biological_process 73 biological_process 910 protein binding 74 protein binding 1067 nucleus 72 cellular_component 910 biological_process 73 molecular_function 952 cellular protein modification process 59 cellular nitrogen compound metabolic process 440 molecular_function 72 molecular_function 952 cellular_component 66 nucleus 884 molecular_function 72 biological_process 910 catabolic process 50 small molecule metabolic process 327 ubiquitin-specific protease activity 67 RNA binding 358 cytoplasm 49 organelle 747 nucleus 72 cellular_component 910 ubiquitin-dependent protein catabolic process 49 signal transduction 250 peptidase activity 66 ion binding 352 organelle 47 cytoplasm 744 ubiquitin-specific protease activity 67 nucleus 884 protein deubiquitination 48 catabolic process 248 ubiquitinyl hydrolase activity 42 poly(A) RNA binding 276 cytosol 28 cytosol 573 cellular_component 66 organelle 747 cellular nitrogen compound metabolic process 21 cellular protein modification process 247 ubiquitin thiolesterase activity 35 ATP binding 194 protein complex 17 protein complex 388 peptidase activity 66 cytoplasm 744 proteolysis 19 biosynthetic process 239 ion binding 26 DNA binding 147 nucleoplasm 12 membrane 297 cellular protein modification process 59 cytosol 573 protein K48-linked deubiquitination 18 response to stress 180 cysteine-type endopeptidase activity 18 enzyme binding 137 extracellular vesicular exosome 10 nucleoplasm 291 catabolic process 50 cellular nitrogen compound metabolic process 440 protein K63-linked deubiquitination 17 transport 158 zinc ion binding 17 ATPase activity 102 plasma membrane 10 extracellular vesicular exosome 272 cytoplasm 49 protein complex 388 response to stress 17 gene expression 133 cysteine-type peptidase activity 16 nucleic acid binding 92 membrane 6 plasma membrane 225 ubiquitin-dependent protein catabolic process 49 RNA binding 358 signal transduction 12 cellular component assembly 128 enzyme binding 10 peptidase activity 90 microtubule organizing center 6 mitochondrion 217 protein deubiquitination 48 ion binding 352 DNA metabolic process 10 nucleobase-containing compound catabolic process 107 metal ion binding 10 structural molecule activity 88 centrosome 5 nucleolus 167 organelle 47 small molecule metabolic process 327 biosynthetic process 9 macromolecular complex assembly 105 small conjugating protein binding 10 zinc ion binding 74 eukaryotic translation initiation factor 3 complex 5 cytoskeleton 92 ubiquitinyl hydrolase activity 42 membrane 297 cell cycle 9 DNA metabolic process 101 omega peptidase activity 9 metal ion binding 72 intracellular 5 Golgi apparatus 91 ubiquitin thiolesterase activity 35 nucleoplasm 291 cell proliferation 9 cell cycle 100 RNA binding 7 ubiquitin-specific protease activity 69 lysosome 5 endoplasmic reticulum 82 cytosol 28 poly(A) RNA binding 276 cell death 7 cell death 99 histone binding 6 identical protein binding 58 proteasome complex 5 extracellular space 79 ion binding 26 extracellular vesicular exosome 272 immune system process 7 immune system process 99 ubiquitin binding 6 helicase activity 57 COP9 signalosome 4 intracellular 59 cellular nitrogen compound metabolic process 21 signal transduction 250 cellular component assembly 6 symbiosis, encompassing mutualism through parasitism 99 enzyme regulator activity 5 nucleotide binding 57 Golgi apparatus 4 integral component of membrane 53 proteolysis 19 catabolic process 248 DNA repair 6 viral process 96 metallopeptidase activity 5 binding 53 mitochondrion 4 microtubule organizing center 45 cysteine-type endopeptidase activity 18 cellular protein modification process 247 gene expression 6 translation 89 poly(A) RNA binding 5 cytoskeletal protein binding 52 nucleolus 4 intracellular membrane-bounded organelle 42 protein K48-linked deubiquitination 18 biosynthetic process 239 macromolecular complex assembly 6 mRNA processing 83 translation initiation factor activity 5 kinase activity 51 cytoplasmic membrane-bounded vesicle 3 intermediate filament 41 protein complex 17 plasma membrane 225 protein K11-linked deubiquitination 6 carbohydrate metabolic process 81 ubiquitin protein ligase binding 5 enzyme regulator activity 49 endosome 3 focal adhesion 40 protein K63-linked deubiquitination 17 mitochondrion 217 small molecule metabolic process 6 ubiquitin-dependent protein catabolic process 81 identical protein binding 4 ligase activity 49 midbody 3 centrosome 38 response to stress 17 ATP binding 194 translation 6 membrane organization 80 protein binding transcription factor activity 4 transcription factor binding 49 vacuole 3 nuclear envelope 38 zinc ion binding 17 response to stress 180 mitotic nuclear division 5 transcription, DNA-templated 80 transcription coactivator activity 4 ubiquitin-protein transferase activity 47 cleavage furrow 2 extracellular region 37 cysteine-type peptidase activity 16 nucleolus 167 transcription, DNA-templated 5 mitotic cell cycle 76 DNA binding 3 ubiquitinyl hydrolase activity 46 early endosome 2 mitochondrial inner membrane 35 nucleoplasm 12 transport 158 translational initiation 5 apoptotic process 71 Lys48-specific deubiquitinase activity 3 oxidoreductase activity 42 endoplasmic reticulum 2 proteasome complex 35 signal transduction 12 DNA binding 147 apoptotic process 4 protein complex assembly 70 proteasome binding 3 protein homodimerization activity 42 endoplasmic reticulum membrane 2 mitochondrial matrix 33 DNA metabolic process 10 enzyme binding 137 cellular amino acid metabolic process 4 regulation of transcription, DNA-templated 68 translation factor activity, nucleic acid binding 3 translation factor activity, nucleic acid binding 42 eukaryotic 43S preinitiation complex 2 perinuclear region of cytoplasm 33 enzyme binding 10 gene expression 133 histone deubiquitination 4 metabolic process 67 chromatin binding 2 signal transducer activity 41 eukaryotic 48S preinitiation complex 2 endosome 30 extracellular vesicular exosome 10 cellular component assembly 128 metabolic process 4 ATP catabolic process 64 endopeptidase inhibitor activity 2 translation initiation factor activity 41 eukaryotic translation initiation factor 3 complex, eIF3m 2 proteasome accessory complex 28 metal ion binding 10 nucleobase-containing compound catabolic process 107 monoubiquitinated protein deubiquitination 4 cellular protein metabolic process 62 G-protein coupled receptor binding 2 calcium ion binding 40 extracellular space 2 catalytic step 2 spliceosome 26 plasma membrane 10 macromolecular complex assembly 105 mRNA processing 4 cytoskeleton organization 62 hydrolase activity 2 catalytic activity 38 integral component of membrane 2 eukaryotic translation initiation factor 3 complex 26 small conjugating protein binding 10 ATPase activity 102 negative regulation of transcription from RNA polymerase II promoter 4 DNA repair 62 K63-linked polyubiquitin binding 2 protein kinase binding 36 proteasome accessory complex 2 ribosome 26 biosynthetic process 9 DNA metabolic process 101 regulation of transcription, DNA-templated 4 vesicle-mediated transport 62 ligase activity 2 protein serine/threonine kinase activity 36 acrosomal vesicle 1 COP9 signalosome 25 cell cycle 9 cell cycle 100 ribonucleoprotein complex assembly 4 anatomical structure development 58 Lys63-specific deubiquitinase activity 2 ubiquitin thiolesterase activity 36 axon 1 ribonucleoprotein complex 25 cell proliferation 9 cell death 99 symbiosis, encompassing mutualism through parasitism 4 RNA metabolic process 57 NEDD8-specific protease activity 2 hydrolase activity 33 BRCA1-A complex 1 endoplasmic reticulum membrane 24 omega peptidase activity 9 immune system process 99 viral process 4 RNA splicing 56 p53 binding 2 unfolded protein binding 33 BRISC complex 1 actin cytoskeleton 23 cell death 7 symbiosis, encompassing mutualism through parasitism 99 anatomical structure development 3 transmembrane transport 55 protein kinase binding 2 protein binding transcription factor activity 32 Cajal body 1 microtubule 23 immune system process 7 viral process 96 autophagy 3 cell differentiation 53 SUMO binding 2 protein complex binding 30 cell body 1 neuronal cell body 22 RNA binding 7 cytoskeleton 92 cell migration 3 cell proliferation 53 transcription factor binding 2 structural constituent of ribosome 30 cell cortex 1 spliceosomal complex 21 cellular component assembly 6 nucleic acid binding 92 cellular response to DNA damage stimulus 3 protein folding 53 3'-5'-exoribonuclease activity 1 mRNA binding 29 cell junction 1 chromosome 20 DNA repair 6 Golgi apparatus 91 cytoskeleton organization 3 mRNA metabolic process 52 adenosine receptor binding 1 protein kinase activity 29 cell surface 1 cytoplasmic mRNA processing body 19 gene expression 6 peptidase activity 90 G1/S transition of mitotic cell cycle 3 protein deubiquitination 51 alpha-2A adrenergic receptor binding 1 ubiquitin protein ligase binding 29 cytoplasmic microtubule 1 nuclear pore 19 histone binding 6 translation 89 innate immune response 3 protein ubiquitination 50 ATPase binding 1 actin binding 27 cytoplasmic mRNA processing body 1 cell-cell junction 18 macromolecular complex assembly 6 structural molecule activity 88 mitotic cell cycle 3 oxidation-reduction process 49 calcium ion binding 1 lipid binding 27 cytoskeleton 1 keratin filament 18 membrane 6 mRNA processing 83 monoubiquitinated histone H2A deubiquitination 3 mRNA splicing, via spliceosome 47 catalytic activity 1 transferase activity, transferring phosphorus-containing groups 27 extrinsic component of cytoplasmic side of plasma membrane 1 lysosome 18 microtubule organizing center 6 endoplasmic reticulum 82 mRNA metabolic process 3 negative regulation of apoptotic process 45 core promoter sequence-specific DNA binding 1 chromatin binding 26 extrinsic component of plasma membrane 1 nuclear membrane 18 protein K11-linked deubiquitination 6 carbohydrate metabolic process 81 negative regulation of I-kappaB kinase/NF-kappaB signaling 3 translational initiation 45 cyclin binding 1 protein domain specific binding 24 Ino80 complex 1 cell junction 17 small molecule metabolic process 6 ubiquitin-dependent protein catabolic process 81 negative regulation of NF-kappaB transcription factor activity 3 cellular amino acid metabolic process 44 endopeptidase activator activity 1 transcription coactivator activity 24 intermediate filament cytoskeleton 1 cytoplasmic membrane-bounded vesicle 17 translation 6 membrane organization 80 negative regulation of skeletal muscle tissue development 3 protein phosphorylation 44 exonuclease activity 1 actin filament binding 23 mitochondrial matrix 1 intermediate filament cytoskeleton 17 ubiquitin binding 6 transcription, DNA-templated 80 negative regulation of type I interferon production 3 G1/S transition of mitotic cell cycle 42 H4 histone acetyltransferase activity 1 cysteine-type endopeptidase activity 23 mitochondrial membrane 1 mitochondrial nucleoid 17 centrosome 5 extracellular space 79 positive regulation of transcription from RNA polymerase II promoter 3 proteolysis 42 ion channel binding 1 small conjugating protein binding 23 mitochondrial outer membrane 1 integral component of plasma membrane 16 enzyme regulator activity 5 mitotic cell cycle 76 positive regulation of transcription, DNA-templated 3 ribonucleoprotein complex assembly 42 kinase binding 1 cysteine-type peptidase activity 21 neuronal cell body 1 neuron projection 16 eukaryotic translation initiation factor 3 complex 5 zinc ion binding 74 proteasome-mediated ubiquitin-dependent protein catabolic process 3 innate immune response 40 ligand-dependent nuclear receptor transcription coactivator activity 1 histone binding 21 nuclear chromatin 1 peroxisome 16 intracellular 5 metal ion binding 72 regulation of apoptotic process 3 protein polyubiquitination 39 NAD+ ADP-ribosyltransferase activity 1 sequence-specific DNA binding transcription factor activity 21 nuclear inclusion body 1 Z disc 16 lysosome 5 apoptotic process 71 regulation of proteasomal protein catabolic process 3 negative regulation of transcription, DNA-templated 37 nuclease activity 1 transmembrane transporter activity 21 nuclear ubiquitin ligase complex 1 midbody 15 metallopeptidase activity 5 protein complex assembly 70 regulation of protein stability 3 lipid metabolic process 36 nucleic acid binding 1 GTP binding 20 PAN complex 1 tight junction 15 mitotic nuclear division 5 ubiquitin-specific protease activity 69 RNA metabolic process 3 mitotic nuclear division 36 nucleotidyltransferase activity 1 transferase activity, transferring acyl groups 20 perinuclear region of cytoplasm 1 cell projection 14 poly(A) RNA binding 5 regulation of transcription, DNA-templated 68 transport 3 negative regulation of transcription from RNA polymerase II promoter 34 poly(A)-specific ribonuclease activity 1 protein heterodimerization activity 19 PR-DUB complex 1 microtubule cytoskeleton 14 proteasome complex 5 metabolic process 67 vesicle-mediated transport 3 antigen processing and presentation of peptide antigen via MHC class I 32 polyubiquitin binding 1 protein tyrosine kinase activity 19 proteasome regulatory particle 1 nuclear speck 14 transcription, DNA-templated 5 ATP catabolic process 64 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process 2 DNA replication 32 proline-rich region binding 1 structural constituent of cytoskeleton 19 proteasome regulatory particle, lid subcomplex 1 chromatin 13 translation initiation factor activity 5 cellular protein metabolic process 62 antigen processing and presentation of exogenous peptide antigen via MHC class I 2 generation of precursor metabolites and energy 32 protease binding 1 ATP-dependent helicase activity 18 RNA polymerase transcription factor SL1 complex 1 eukaryotic 43S preinitiation complex 13 translational initiation 5 cytoskeleton organization 62 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent 2 nucleocytoplasmic transport 32 protein C-terminus binding 1 nucleic acid binding transcription factor activity 17 SAGA-type complex 1 eukaryotic 48S preinitiation complex 13 ubiquitin protein ligase binding 5 DNA repair 62 antigen processing and presentation of peptide antigen via MHC class I 2 positive regulation of transcription from RNA polymerase II promoter 31 protein homodimerization activity 1 calmodulin binding 16 SAGA complex 1 nuclear chromatin 13 apoptotic process 4 vesicle-mediated transport 62 axon guidance 2 regulation of apoptotic process 31 protein self-association 1 GTPase activity 16 spliceosomal complex 1 stress fiber 13 cellular amino acid metabolic process 4 intracellular 59 B-1 B cell homeostasis 2 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process 30 SH3 domain binding 1 lyase activity 16 synapse 1 axon 12 COP9 signalosome 4 anatomical structure development 58 cell differentiation 2 cell adhesion 30 SMAD binding 1 microtubule binding 16 synaptic vesicle 1 cell body 12 Golgi apparatus 4 identical protein binding 58 cell motility 2 homeostatic process 30 SUMO-specific isopeptidase activity 1 protein binding, bridging 16 ubiquitin ligase complex 1 nuclear chromosome 12 histone deubiquitination 4 helicase activity 57 cellular protein metabolic process 2 transcription from RNA polymerase II promoter 30 transferase activity, transferring acyl groups 1 magnesium ion binding 15 VCB complex 1 sarcolemma 12 identical protein binding 4 nucleotide binding 57 cellular response to hydrogen peroxide 2 axon guidance 29 transferase activity, transferring glycosyl groups 1 protein C-terminus binding 15 trans-Golgi network 12 metabolic process 4 RNA metabolic process 57 cullin deneddylation 2 protein targeting 29 transforming growth factor beta receptor binding 1 nucleotidyltransferase activity 14 vesicle 12 mitochondrion 4 RNA splicing 56 DNA damage response, signal transduction by p53 class mediator 2 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 29 translation initiation factor binding 1 chaperone binding 13 apical plasma membrane 11 monoubiquitinated protein deubiquitination 4 transmembrane transport 55 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest 2 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 28 tRNA guanylyltransferase activity 1 damaged DNA binding 13 Cajal body 11 mRNA processing 4 binding 53 embryo development 2 cellular response to DNA damage stimulus 27 ubiquitin-protein transferase activity 1 methyltransferase activity 13 cell surface 11 negative regulation of transcription from RNA polymerase II promoter 4 cell differentiation 53 endocytosis 2 locomotion 27 microtubule motor activity 13 endoplasmic reticulum lumen 11 nucleolus 4 cell proliferation 53 ER-associated ubiquitin-dependent protein catabolic process 2 protein transport 27 receptor binding 13 Golgi membrane 11 protein binding transcription factor activity 4 integral component of membrane 53 formation of translation preinitiation complex 2 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 25 sequence-specific DNA binding 13 lamellipodium 11 regulation of transcription, DNA-templated 4 protein folding 53 histone H2A K63-linked deubiquitination 2 positive regulation of transcription, DNA-templated 25 single-stranded DNA binding 13 MCM complex 11 ribonucleoprotein complex assembly 4 cytoskeletal protein binding 52 locomotion 2 antigen processing and presentation of exogenous peptide antigen via MHC class I 24 transporter activity 13 protein phosphatase type 2A complex 11 symbiosis, encompassing mutualism through parasitism 4 mRNA metabolic process 52 mitochondrial fusion 2 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent 24 double-stranded RNA binding 12 vacuole 11 transcription coactivator activity 4 kinase activity 51 mitotic cytokinesis 2 cytokine-mediated signaling pathway 24 nuclease activity 12 cell cortex 10 viral process 4 protein deubiquitination 51 mucosal immune response 2 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest 24 phosphatase activity 12 Cul3-RING ubiquitin ligase complex 10 anatomical structure development 3 protein ubiquitination 50 necroptotic process 2 in utero embryonic development 24 transcription corepressor activity 12 growth cone 10 autophagy 3 enzyme regulator activity 49 negative regulation of apoptotic process 2 blood coagulation 23 DNA helicase activity 11 kinetochore 10 cell migration 3 ligase activity 49 negative regulation of B cell activation 2 cofactor metabolic process 23 motor activity 11 nuclear matrix 10 cellular response to DNA damage stimulus 3 oxidation-reduction process 49 negative regulation of endopeptidase activity 2 spermatogenesis 23 transferase activity, transferring glycosyl groups 11 proteasome regulatory particle 10 cytoplasmic membrane-bounded vesicle 3 transcription factor binding 49 negative regulation of inflammatory response 2 chromosome organization 22 aminoacyl-tRNA ligase activity 10 cytoplasmic vesicle 9 cytoskeleton organization 3 mRNA splicing, via spliceosome 47 negative regulation of innate immune response 2 intracellular protein transport 22 ATP-dependent DNA helicase activity 10 dendritic spine 9 DNA binding 3 ubiquitin-protein transferase activity 47 negative regulation of interleukin-6 production 2 negative regulation of cell proliferation 22 carbohydrate binding 10 kinesin complex 9 endosome 3 ubiquitinyl hydrolase activity 46 negative regulation of protein ubiquitination 2 regulation of cellular amino acid metabolic process 22 four-way junction helicase activity 10 mitochondrial small ribosomal subunit 9 G1/S transition of mitotic cell cycle 3 microtubule organizing center 45 negative regulation of transforming growth factor beta receptor signaling pathway 2 regulation of translational initiation 22 isomerase activity 10 myosin complex 9 innate immune response 3 negative regulation of apoptotic process 45 negative regulation of tumor necrosis factor production 2 aging 21 protein N-terminus binding 10 synapse 9 Lys48-specific deubiquitinase activity 3 translational initiation 45 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 2 cell motility 21 protein phosphatase binding 10 ubiquitin ligase complex 9 midbody 3 cellular amino acid metabolic process 44 nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway 2 double-strand break repair 21 transcription regulatory region DNA binding 10 apical part of cell 8 mitotic cell cycle 3 protein phosphorylation 44 nucleotide-binding oligomerization domain containing signaling pathway 2 proteasome-mediated ubiquitin-dependent protein catabolic process 21 ubiquitin binding 10 basolateral plasma membrane 8 monoubiquitinated histone H2A deubiquitination 3 G1/S transition of mitotic cell cycle 42 positive regulation of mitotic cell cycle 2 extracellular matrix organization 20 DNA-directed RNA polymerase activity 9 chaperonin-containing T-complex 8 mRNA metabolic process 3 intracellular membrane-bounded organelle 42 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 2 rRNA processing 20 double-stranded DNA binding 9 cilium 8 negative regulation of I-kappaB kinase/NF-kappaB signaling 3 oxidoreductase activity 42 protein complex assembly 2 tRNA aminoacylation for protein translation 20 histone deacetylase binding 9 cullin-RING ubiquitin ligase complex 8 negative regulation of NF-kappaB transcription factor activity 3 protein homodimerization activity 42 protein K29-linked deubiquitination 2 tRNA metabolic process 20 iron ion binding 9 cytoplasmic stress granule 8 negative regulation of skeletal muscle tissue development 3 proteolysis 42 protein K33-linked deubiquitination 2 DNA recombination 19 omega peptidase activity 9 early endosome 8 negative regulation of type I interferon production 3 ribonucleoprotein complex assembly 42 protein polyubiquitination 2 RNA processing 19 polyubiquitin binding 9 extracellular matrix 8 positive regulation of transcription from RNA polymerase II promoter 3 translation factor activity, nucleic acid binding 42 protein stabilization 2 epidermal growth factor receptor signaling pathway 18 protein dimerization activity 9 nuclear inclusion body 8 positive regulation of transcription, DNA-templated 3 intermediate filament 41 protein ubiquitination 2 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 18 pyridoxal phosphate binding 9 postsynaptic membrane 8 proteasome-mediated ubiquitin-dependent protein catabolic process 3 signal transducer activity 41 regulation of autophagy 2 positive regulation of apoptotic process 18 receptor activity 9 proteasome core complex 8 proteasome binding 3 translation initiation factor activity 41 regulation of cell cycle 2 protein K48-linked deubiquitination 18 ADP binding 8 SCF ubiquitin ligase complex 8 regulation of apoptotic process 3 calcium ion binding 40 regulation of cellular amino acid metabolic process 2 protein K63-linked deubiquitination 18 ion channel binding 8 spindle 8 regulation of proteasomal protein catabolic process 3 focal adhesion 40 regulation of defense response to virus by host 2 response to drug 18 mRNA 3'-UTR binding 8 zona pellucida receptor complex 8 regulation of protein stability 3 innate immune response 40 regulation of G-protein coupled receptor protein signaling pathway 2 cell junction organization 17 NAD binding 8 blood microparticle 7 RNA metabolic process 3 protein polyubiquitination 39 regulation of germinal center formation 2 chromatin organization 17 p53 binding 8 chromosome, centromeric region 7 translation factor activity, nucleic acid binding 3 catalytic activity 38 regulation of synaptic transmission, GABAergic 2 osteoblast differentiation 17 protease binding 8 cortical cytoskeleton 7 transport 3 centrosome 38 regulation of transcription from RNA polymerase II promoter 2 regulation of transcription from RNA polymerase II promoter 17 protein transporter activity 8 cytoplasmic vesicle membrane 7 vacuole 3 nuclear envelope 38 regulation of translational initiation 2 fibroblast growth factor receptor signaling pathway 16 ribosome binding 8 desmosome 7 vesicle-mediated transport 3 extracellular region 37 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 2 G2/M transition of mitotic cell cycle 16 transcription cofactor activity 8 eukaryotic translation initiation factor 3 complex, eIF3m 7 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process 2 negative regulation of transcription, DNA-templated 37 response to ionizing radiation 2 intracellular signal transduction 16 ATP-dependent RNA helicase activity 7 eukaryotic translation initiation factor 4F complex 7 antigen processing and presentation of exogenous peptide antigen via MHC class I 2 lipid metabolic process 36 response to molecule of bacterial origin 2 neurotrophin TRK receptor signaling pathway 16 glycoprotein binding 7 inclusion body 7 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent 2 mitotic nuclear division 36 synaptic transmission 2 nucleotide-excision repair 16 heat shock protein binding 7 intercalated disc 7 antigen processing and presentation of peptide antigen via MHC class I 2 protein kinase binding 36 transforming growth factor beta receptor signaling pathway 2 positive regulation of cell proliferation 16 histone acetyltransferase activity 7 lateral plasma membrane 7 axon guidance 2 protein serine/threonine kinase activity 36 Wnt signaling pathway 2 protein maturation 16 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors 7 lipid particle 7 B-1 B cell homeostasis 2 ubiquitin thiolesterase activity 36 actin cytoskeleton organization 1 glucose metabolic process 15 peptidyl-prolyl cis-trans isomerase activity 7 mitochondrial intermembrane space 7 cell differentiation 2 mitochondrial inner membrane 35 adult feeding behavior 1 intrinsic apoptotic signaling pathway 15 phospholipid binding 7 myosin II complex 7 cell motility 2 proteasome complex 35 adult walking behavior 1 mitochondrion organization 15 protein kinase C binding 7 nuclear heterochromatin 7 cellular protein metabolic process 2 negative regulation of transcription from RNA polymerase II promoter 34 axon target recognition 1 mitotic nuclear envelope disassembly 15 protein phosphatase type 2A regulator activity 7 sarcomere 7 cellular response to hydrogen peroxide 2 hydrolase activity 33 axon transport of mitochondrion 1 mRNA export from nucleus 15 protein serine/threonine phosphatase activity 7 spindle pole 7 chromatin binding 2 mitochondrial matrix 33 axonogenesis 1 multicellular organismal development 15 structural constituent of muscle 7 transcription factor complex 7 cleavage furrow 2 perinuclear region of cytoplasm 33 behavioral fear response 1 antigen processing and presentation of exogenous peptide antigen via MHC class II 14 3-hydroxyacyl-CoA dehydrogenase activity 6 actin filament 6 cullin deneddylation 2 unfolded protein binding 33 behavioral response to ethanol 1 DNA duplex unwinding 14 electron carrier activity 6 BRCA1-A complex 6 DNA damage response, signal transduction by p53 class mediator 2 antigen processing and presentation of peptide antigen via MHC class I 32 BMP signaling pathway 1 protein dephosphorylation 14 heme binding 6 cell-cell adherens junction 6 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest 2 DNA replication 32 CAAX-box protein processing 1 small GTPase mediated signal transduction 14 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 6 cell periphery 6 early endosome 2 generation of precursor metabolites and energy 32 Cajal body organization 1 cell-cell signaling 13 hydrolase activity, acting on glycosyl bonds 6 chromosome, telomeric region 6 embryo development 2 nucleocytoplasmic transport 32 cell-cell signaling 1 cell cycle arrest 13 magnesium chelatase activity 6 clathrin-coated vesicle 6 endocytosis 2 protein binding transcription factor activity 32 cell cycle checkpoint 1 cell division 13 metallopeptidase activity 6 cleavage furrow 6 endopeptidase inhibitor activity 2 positive regulation of transcription from RNA polymerase II promoter 31 cell division 1 cellular metabolic process 13 nucleocytoplasmic transporter activity 6 condensed nuclear chromosome 6 endoplasmic reticulum 2 regulation of apoptotic process 31 cellular response to heat 1 ER to Golgi vesicle-mediated transport 13 phosphoprotein binding 6 COPII vesicle coat 6 endoplasmic reticulum membrane 2 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process 30 cellular response to lipopolysaccharide 1 Fc-epsilon receptor signaling pathway 13 phosphoprotein phosphatase activity 6 costamere 6 ER-associated ubiquitin-dependent protein catabolic process 2 cell adhesion 30 cellular response to misfolded protein 1 formation of translation preinitiation complex 13 ribonucleoprotein complex binding 6 dendrite 6 eukaryotic 43S preinitiation complex 2 endosome 30 cellular response to UV 1 microtubule-based movement 13 RNA cap binding 6 DNA-directed RNA polymerase I complex 6 eukaryotic 48S preinitiation complex 2 homeostatic process 30 centrosome duplication 1 platelet activation 13 structural constituent of epidermis 6 filopodium 6 eukaryotic translation initiation factor 3 complex, eIF3m 2 protein complex binding 30 chromatin organization 1 regulation of cell cycle 13 actin-dependent ATPase activity 5 nuclear euchromatin 6 extracellular space 2 structural constituent of ribosome 30 cytokine-mediated signaling pathway 1 Wnt signaling pathway 13 ankyrin binding 5 nuclear pore nuclear basket 6 formation of translation preinitiation complex 2 transcription from RNA polymerase II promoter 30 DNA damage checkpoint 1 actin cytoskeleton organization 12 cadherin binding 5 peroxisomal membrane 6 G-protein coupled receptor binding 2 axon guidance 29 DNA recombination 1 anatomical structure formation involved in morphogenesis 12 drug binding 5 polysome 6 histone H2A K63-linked deubiquitination 2 mRNA binding 29 double-strand break repair 1 cellular component disassembly involved in execution phase of apoptosis 12 G-protein coupled receptor binding 5 secretory granule 6 hydrolase activity 2 protein kinase activity 29 double-strand break repair via homologous recombination 1 chromosome segregation 12 guanyl-nucleotide exchange factor activity 5 synaptic vesicle 6 integral component of membrane 2 protein targeting 29 double-strand break repair via nonhomologous end joining 1 glucose transport 12 ligand-dependent nuclear receptor transcription coactivator activity 5 transcription elongation factor complex 6 K63-linked polyubiquitin binding 2 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 29 eating behavior 1 hexose transport 12 microfilament motor activity 5 U5 snRNP 6 ligase activity 2 ubiquitin protein ligase binding 29 endoplasmic reticulum membrane fusion 1 mRNA transport 12 phosphatase binding 5 acrosomal vesicle 5 locomotion 2 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 28 endoplasmic reticulum unfolded protein response 1 phosphorylation 12 protein phosphatase 2A binding 5 BRISC complex 5 Lys63-specific deubiquitinase activity 2 proteasome accessory complex 28 endosome organization 1 regulation of glucose transport 12 protein tyrosine phosphatase activity 5 cell leading edge 5 mitochondrial fusion 2 actin binding 27 establishment of protein localization to vacuole 1 telomere maintenance 12 Rac GTPase binding 5 coated pit 5 mitotic cytokinesis 2 cellular response to DNA damage stimulus 27 exosomal secretion 1 transcription elongation from RNA polymerase II promoter 12 Ran GTPase binding 5 Cul4A-RING E3 ubiquitin ligase complex 5 mucosal immune response 2 lipid binding 27 forebrain morphogenesis 1 transcription from RNA polymerase I promoter 12 RNA polymerase I activity 5 cytosolic large ribosomal subunit 5 necroptotic process 2 locomotion 27 G2 DNA damage checkpoint 1 cell migration 11 rRNA binding 5 dystrophin-associated glycoprotein complex 5 NEDD8-specific protease activity 2 protein transport 27 Golgi organization 1 epidermis development 11 scaffold protein binding 5 Ino80 complex 5 negative regulation of apoptotic process 2 transferase activity, transferring phosphorus-containing groups 27 Golgi reassembly 1 muscle contraction 11 SH3 domain binding 5 membrane raft 5 negative regulation of B cell activation 2 catalytic step 2 spliceosome 26 histone H2B conserved C-terminal lysine deubiquitination 1 negative regulation of catalytic activity 11 translation initiation factor binding 5 mitochondrial outer membrane 5 negative regulation of endopeptidase activity 2 chromatin binding 26 histone H4 acetylation 1 negative regulation of translation 11 tRNA binding 5 mitochondrial ribosome 5 negative regulation of inflammatory response 2 eukaryotic translation initiation factor 3 complex 26 histone ubiquitination 1 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 11 3'-5' exonuclease activity 4 MLL1 complex 5 negative regulation of innate immune response 2 ribosome 26 homeostatic process 1 protein ubiquitination involved in ubiquitin-dependent protein catabolic process 11 acyl-CoA dehydrogenase activity 4 mRNA cap binding complex 5 negative regulation of interleukin-6 production 2 COP9 signalosome 25 inflammatory response 1 regulation of cell proliferation 11 adenosylhomocysteinase activity 4 nuclear chromosome, telomeric region 5 negative regulation of protein ubiquitination 2 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 25 intermediate filament cytoskeleton organization 1 sulfur compound metabolic process 11 aminopeptidase activity 4 nuclear inner membrane 5 negative regulation of transforming growth factor beta receptor signaling pathway 2 positive regulation of transcription, DNA-templated 25 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 1 transcription initiation from RNA polymerase I promoter 11 antioxidant activity 4 nuclear periphery 5 negative regulation of tumor necrosis factor production 2 ribonucleoprotein complex 25 JAK-STAT cascade 1 translational elongation 11 ATP-dependent peptidase activity 4 PcG protein complex 5 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 2 antigen processing and presentation of exogenous peptide antigen via MHC class I 24 lateral ventricle development 1 brain development 10 calcium-dependent phospholipid binding 4 PML body 5 nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway 2 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent 24 maintenance of DNA methylation 1 endoplasmic reticulum unfolded protein response 10 core promoter binding 4 replication fork 5 nucleotide-binding oligomerization domain containing signaling pathway 2 cytokine-mediated signaling pathway 24 melanocyte differentiation 1 GTP catabolic process 10 CTP synthase activity 4 RISC complex 5 p53 binding 2 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest 24 membrane organization 1 muscle organ development 10 cyclin binding 4 ruffle 5 positive regulation of mitotic cell cycle 2 endoplasmic reticulum membrane 24 microtubule cytoskeleton organization 1 negative regulation of neuron apoptotic process 10 DNA-directed DNA polymerase activity 4 small ribosomal subunit 5 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 2 in utero embryonic development 24 midbrain development 1 nucleobase-containing small molecule metabolic process 10 endopeptidase activity 4 spindle microtubule 5 proteasome accessory complex 2 protein domain specific binding 24 misfolded or incompletely synthesized protein catabolic process 1 phosphatidylinositol-mediated signaling 10 ephrin receptor binding 4 STAGA complex 5 protein complex assembly 2 transcription coactivator activity 24 mitochondrion degradation 1 positive regulation of DNA repair 10 flavin adenine dinucleotide binding 4 aggresome 4 protein K29-linked deubiquitination 2 actin cytoskeleton 23 mitochondrion organization 1 positive regulation of gene expression 10 formate-tetrahydrofolate ligase activity 4 axoneme 4 protein K33-linked deubiquitination 2 actin filament binding 23 mitotic cell cycle checkpoint 1 positive regulation of I-kappaB kinase/NF-kappaB signaling 10 G-protein beta/gamma-subunit complex binding 4 centriole 4 protein kinase binding 2 blood coagulation 23 mRNA splicing, via spliceosome 1 positive regulation of translation 10 glucose binding 4 ciliary basal body 4 protein polyubiquitination 2 cofactor metabolic process 23 multicellular organismal development 1 positive regulation of type I interferon production 10 glycogen (starch) synthase activity 4 cis-Golgi network 4 protein stabilization 2 cysteine-type endopeptidase activity 23 muscle fiber development 1 protein N-linked glycosylation via asparagine 10 GTPase activator activity 4 Cul4-RING E3 ubiquitin ligase complex 4 protein ubiquitination 2 microtubule 23 muscle organ development 1 protein stabilization 10 Hsp90 protein binding 4 Cul4B-RING E3 ubiquitin ligase complex 4 regulation of autophagy 2 small conjugating protein binding 23 negative regulation of bone resorption 1 regulation of translation 10 K63-linked polyubiquitin binding 4 cytoplasmic microtubule 4 regulation of cell cycle 2 spermatogenesis 23 negative regulation of canonical Wnt signaling pathway 1 response to hypoxia 10 kinase binding 4 cytoplasmic side of plasma membrane 4 regulation of cellular amino acid metabolic process 2 chromosome organization 22 negative regulation of CD40 signaling pathway 1 response to unfolded protein 10 MHC class II protein complex binding 4 DNA-directed RNA polymerase II, core complex 4 regulation of defense response to virus by host 2 intracellular protein transport 22 negative regulation of cell death 1 response to UV 10 miRNA binding 4 Elongator holoenzyme complex 4 regulation of G-protein coupled receptor protein signaling pathway 2 negative regulation of cell proliferation 22 negative regulation of cell proliferation 1 response to virus 10 mismatched DNA binding 4 endoplasmic reticulum-Golgi intermediate compartment 4 regulation of germinal center formation 2 neuronal cell body 22 negative regulation of chronic inflammatory response 1 RNA splicing, via transesterification reactions 10 N-acetyltransferase activity 4 endosome membrane 4 regulation of synaptic transmission, GABAergic 2 regulation of cellular amino acid metabolic process 22 negative regulation of cyclin-dependent protein serine/threonine kinase activity 1 single organismal cell-cell adhesion 10 NAD+ ADP-ribosyltransferase activity 4 ER to Golgi transport vesicle membrane 4 regulation of transcription from RNA polymerase II promoter 2 regulation of translational initiation 22 negative regulation of double-strand break repair 1 SRP-dependent cotranslational protein targeting to membrane 10 NADP binding 4 exon-exon junction complex 4 regulation of translational initiation 2 aging 21 negative regulation of endothelial cell apoptotic process 1 toxin transport 10 neutral amino acid transmembrane transporter activity 4 exosome (RNase complex) 4 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 2 cell motility 21 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors 1 transcription initiation from RNA polymerase II promoter 10 NF-kappaB binding 4 extrinsic component of cytoplasmic side of plasma membrane 4 response to ionizing radiation 2 cysteine-type peptidase activity 21 negative regulation of histone deacetylation 1 tRNA processing 10 nitric-oxide synthase regulator activity 4 fascia adherens 4 response to molecule of bacterial origin 2 double-strand break repair 21 negative regulation of histone H2A K63-linked ubiquitination 1 'de novo' posttranslational protein folding 9 phenylalanine-tRNA ligase activity 4 heterochromatin 4 SUMO binding 2 histone binding 21 negative regulation of interleukin-1 beta production 1 autophagy 9 phosphotransferase activity, alcohol group as acceptor 4 Ku70:Ku80 complex 4 synaptic transmission 2 proteasome-mediated ubiquitin-dependent protein catabolic process 21 negative regulation of interleukin-2 production 1 cell morphogenesis 9 potassium ion binding 4 membrane coat 4 transcription factor binding 2 sequence-specific DNA binding transcription factor activity 21 negative regulation of interleukin-8 production 1 chaperone-mediated protein folding 9 proteasome binding 4 mitochondrial membrane 4 transforming growth factor beta receptor signaling pathway 2 spliceosomal complex 21 negative regulation of MAP kinase activity 1 cullin deneddylation 9 proton-transporting ATP synthase activity, rotational mechanism 4 mitotic spindle 4 Wnt signaling pathway 2 transmembrane transporter activity 21 negative regulation of mitotic anaphase-promoting complex activity 1 DNA strand elongation involved in DNA replication 9 pyruvate kinase activity 4 MutSalpha complex 4 3'-5'-exoribonuclease activity 1 chromosome 20 negative regulation of neuron apoptotic process 1 endocytosis 9 Rab GTPase binding 4 neuromuscular junction 4 acrosomal vesicle 1 extracellular matrix organization 20 negative regulation of NF-kappaB import into nucleus 1 glycolytic process 9 ribosomal small subunit binding 4 nuclear envelope lumen 4 actin cytoskeleton organization 1 GTP binding 20 negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway 1 negative regulation of cell growth 9 RNA helicase activity 4 nuclear pore outer ring 4 adenosine receptor binding 1 rRNA processing 20 negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway 1 negative regulation of NF-kappaB transcription factor activity 9 serine-type endopeptidase inhibitor activity 4 NuRD complex 4 adult feeding behavior 1 transferase activity, transferring acyl groups 20 negative regulation of osteoclast proliferation 1 positive regulation of cell migration 9 single-stranded RNA binding 4 peroxisomal matrix 4 adult walking behavior 1 tRNA aminoacylation for protein translation 20 negative regulation of phosphatidylinositol 3-kinase signaling 1 positive regulation of GTPase activity 9 sodium:potassium-exchanging ATPase activity 4 postsynaptic density 4 alpha-2A adrenergic receptor binding 1 tRNA metabolic process 20 negative regulation of protein localization to nucleus 1 positive regulation of proteasomal ubiquitin-dependent protein catabolic process 9 tau-protein kinase activity 4 proteasome core complex, alpha-subunit complex 4 ATPase binding 1 cytoplasmic mRNA processing body 19 negative regulation of protein processing 1 post-translational protein modification 9 TBP-class protein binding 4 pseudopodium 4 axon 1 DNA recombination 19 negative regulation of protein targeting to membrane 1 protein catabolic process 9 telomeric DNA binding 4 receptor complex 4 axon target recognition 1 nuclear pore 19 negative regulation of Ras GTPase activity 1 protein homotetramerization 9 threonine-type endopeptidase activity 4 sarcoplasmic reticulum 4 axon transport of mitochondrion 1 protein heterodimerization activity 19 negative regulation of Ras protein signal transduction 1 Ras protein signal transduction 9 translation elongation factor activity 4 sodium:potassium-exchanging ATPase complex 4 axonogenesis 1 protein tyrosine kinase activity 19 negative regulation of smooth muscle cell proliferation 1 regulation of gene expression 9 ubiquitin-ubiquitin ligase activity 4 spectrin 4 behavioral fear response 1 RNA processing 19 negative regulation of T cell differentiation 1 response to ionizing radiation 9 3'-5'-exoribonuclease activity 3 U4/U6 x U5 tri-snRNP complex 4 behavioral response to ethanol 1 structural constituent of cytoskeleton 19 negative regulation of toll-like receptor 2 signaling pathway 1 ribosome biogenesis 9 armadillo repeat domain binding 3 zonula adherens 4 BMP signaling pathway 1 ATP-dependent helicase activity 18 negative regulation of toll-like receptor 3 signaling pathway 1 spliceosomal tri-snRNP complex assembly 9 beta-amyloid binding 3 actomyosin 3 BRCA1-A complex 1 cell-cell junction 18 negative regulation of toll-like receptor 4 signaling pathway 1 substantia nigra development 9 beta-catenin binding 3 Ada2/Gcn5/Ada3 transcription activator complex 3 BRISC complex 1 epidermal growth factor receptor signaling pathway 18 negative regulation of toll-like receptor 5 signaling pathway 1 synaptic transmission 9 beta-tubulin binding 3 anaphase-promoting complex 3 CAAX-box protein processing 1 keratin filament 18 nervous system development 1 termination of RNA polymerase I transcription 9 calcium-dependent protein binding 3 apical junction complex 3 Cajal body 1 lysosome 18 neuromuscular process 1 transcription elongation from RNA polymerase I promoter 9 clathrin binding 3 basement membrane 3 Cajal body organization 1 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 18 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 1 transforming growth factor beta receptor signaling pathway 9 collagen binding 3 caveola 3 calcium ion binding 1 nuclear membrane 18 nuclear-transcribed mRNA poly(A) tail shortening 1 ATP biosynthetic process 8 copper ion binding 3 ciliary transition zone 3 catalytic activity 1 positive regulation of apoptotic process 18 nucleobase-containing compound catabolic process 1 binding of sperm to zona pellucida 8 DNA-dependent ATPase activity 3 clathrin-coated endocytic vesicle membrane 3 cell-cell signaling 1 protein K48-linked deubiquitination 18 nucleotide-excision repair 1 cell junction assembly 8 endopeptidase activator activity 3 cohesin core heterodimer 3 cell body 1 protein K63-linked deubiquitination 18 pathway-restricted SMAD protein phosphorylation 1 cellular lipid metabolic process 8 fatty-acyl-CoA binding 3 condensed chromosome 3 cell cortex 1 response to drug 18 positive regulation of cell cycle process 1 cellular protein localization 8 ferrous iron transmembrane transporter activity 3 contractile fiber 3 cell cycle checkpoint 1 cell junction 17 positive regulation of cell proliferation 1 cellular response to hypoxia 8 GTPase inhibitor activity 3 cornified envelope 3 cell division 1 cell junction organization 17 positive regulation of cellular protein catabolic process 1 defense response to virus 8 guanine/thymine mispair binding 3 cortical actin cytoskeleton 3 cell junction 1 chromatin organization 17 positive regulation of DNA repair 1 dephosphorylation 8 heparin binding 3 cytosolic proteasome complex 3 cell surface 1 cytoplasmic membrane-bounded vesicle 17 positive regulation of endopeptidase activity 1 double-strand break repair via nonhomologous end joining 8 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 3 cytosolic small ribosomal subunit 3 cellular response to heat 1 intermediate filament cytoskeleton 17 positive regulation of extrinsic apoptotic signaling pathway 1 G2 DNA damage checkpoint 8 insulin receptor substrate binding 3 dendrite cytoplasm 3 cellular response to lipopolysaccharide 1 mitochondrial nucleoid 17 positive regulation of hepatocyte proliferation 1 inflammatory response 8 iron-sulfur cluster binding 3 DNA-directed RNA polymerase II, holoenzyme 3 cellular response to misfolded protein 1 nucleic acid binding transcription factor activity 17 positive regulation of MDA-5 signaling pathway 1 mitotic spindle assembly checkpoint 8 L-ascorbic acid binding 3 DNA replication factor A complex 3 cellular response to UV 1 osteoblast differentiation 17 positive regulation of proteasomal ubiquitin-dependent protein catabolic process 1 negative regulation of protein ubiquitination 8 L-lactate dehydrogenase activity 3 endocytic vesicle 3 centrosome duplication 1 regulation of transcription from RNA polymerase II promoter 17 positive regulation of protein catabolic process 1 nervous system development 8 lamin binding 3 endocytic vesicle lumen 3 chromatin organization 1 calmodulin binding 16 positive regulation of Rho GTPase activity 1 Notch signaling pathway 8 long-chain-enoyl-CoA hydratase activity 3 endocytic vesicle membrane 3 core promoter sequence-specific DNA binding 1 fibroblast growth factor receptor signaling pathway 16 positive regulation of RIG-I signaling pathway 1 nucleosome assembly 8 low-density lipoprotein particle receptor binding 3 endomembrane system 3 cyclin binding 1 G2/M transition of mitotic cell cycle 16 positive regulation of skeletal muscle tissue development 1 positive regulation of NF-kappaB transcription factor activity 8 Lys48-specific deubiquitinase activity 3 ER to Golgi transport vesicle 3 cytokine-mediated signaling pathway 1 GTPase activity 16 positive regulation of translational elongation 1 protein homooligomerization 8 MAP kinase activity 3 extrinsic component of membrane 3 cytoplasmic microtubule 1 integral component of plasma membrane 16 positive regulation of Wnt signaling pathway 1 protein monoubiquitination 8 methylated histone binding 3 filopodium membrane 3 cytoplasmic mRNA processing body 1 intracellular signal transduction 16 protein catabolic process 1 regulation of alternative mRNA splicing, via spliceosome 8 methylenetetrahydrofolate dehydrogenase (NADP+) activity 3 GAIT complex 3 cytoskeleton 1 lyase activity 16 protein deneddylation 1 retina homeostasis 8 mitogen-activated protein kinase binding 3 histone acetyltransferase complex 3 DNA damage checkpoint 1 microtubule binding 16 protein desumoylation 1 transcription-coupled nucleotide-excision repair 8 nitric-oxide synthase binding 3 I band 3 DNA recombination 1 neuron projection 16 protein deubiquitination involved in ubiquitin-dependent protein catabolic process 1 translational termination 8 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 3 integral component of endoplasmic reticulum membrane 3 double-strand break repair 1 neurotrophin TRK receptor signaling pathway 16 protein homotetramerization 1 cellular component movement 7 peroxisome proliferator activated receptor binding 3 intercellular canaliculus 3 double-strand break repair via homologous recombination 1 nucleotide-excision repair 16 protein K27-linked deubiquitination 1 chromatin modification 7 phosphatidylinositol-3,4,5-trisphosphate binding 3 lamin filament 3 double-strand break repair via nonhomologous end joining 1 peroxisome 16 protein K48-linked ubiquitination 1 chromatin remodeling 7 phosphogluconate dehydrogenase (decarboxylating) activity 3 late endosome 3 eating behavior 1 positive regulation of cell proliferation 16 protein localization to cell surface 1 COPII vesicle coating 7 protein-arginine N-methyltransferase activity 3 lysosomal membrane 3 endopeptidase activator activity 1 protein binding, bridging 16 protein maturation 1 DNA replication initiation 7 protein kinase C inhibitor activity 3 M band 3 endoplasmic reticulum membrane fusion 1 protein maturation 16 protein oligomerization 1 heart development 7 receptor tyrosine kinase binding 3 mast cell granule 3 endoplasmic reticulum unfolded protein response 1 Z disc 16 Ras protein signal transduction 1 insulin receptor signaling pathway 7 Rho GTPase binding 3 mediator complex 3 endosome organization 1 glucose metabolic process 15 regulation of catalytic activity 1 microtubule cytoskeleton organization 7 ribonuclease P activity 3 micro-ribonucleoprotein complex 3 establishment of protein localization to vacuole 1 intrinsic apoptotic signaling pathway 15 regulation of cell-substrate adhesion 1 mitotic cytokinesis 7 RNA methyltransferase activity 3 mitochondrial envelope 3 exonuclease activity 1 magnesium ion binding 15 regulation of cell growth 1 mitotic spindle organization 7 RNA polymerase II core promoter proximal region sequence-specific DNA binding 3 mitochondrial proton-transporting ATP synthase complex 3 exosomal secretion 1 midbody 15 regulation of cell migration 1 multicellular organism growth 7 RNA polymerase II transcription cofactor activity 3 Mre11 complex 3 extrinsic component of cytoplasmic side of plasma membrane 1 mitochondrion organization 15 regulation of cell morphogenesis 1 muscle filament sliding 7 RNA polymerase II transcription factor binding 3 muscle myosin complex 3 extrinsic component of plasma membrane 1 mitotic nuclear envelope disassembly 15 regulation of cell proliferation 1 negative regulation of endopeptidase activity 7 rRNA methyltransferase activity 3 myofibril 3 forebrain morphogenesis 1 mRNA export from nucleus 15 regulation of cellular response to hypoxia 1 neuron migration 7 serine-type endopeptidase activity 3 myosin II filament 3 G2 DNA damage checkpoint 1 multicellular organismal development 15 regulation of chemotaxis 1 one-carbon metabolic process 7 SH3/SH2 adaptor activity 3 nonhomologous end joining complex 3 Golgi organization 1 protein C-terminus binding 15 regulation of DNA repair 1 pentose-phosphate shunt 7 SMAD binding 3 NuA4 histone acetyltransferase complex 3 Golgi reassembly 1 tight junction 15 regulation of intrinsic apoptotic signaling pathway 1 peptidyl-threonine phosphorylation 7 structural constituent of nuclear pore 3 nuclear telomere cap complex 3 H4 histone acetyltransferase activity 1 antigen processing and presentation of exogenous peptide antigen via MHC class II 14 regulation of JNK cascade 1 platelet degranulation 7 SUMO binding 3 paraspeckles 3 histone H2B conserved C-terminal lysine deubiquitination 1 cell projection 14 regulation of microtubule cytoskeleton organization 1 positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway 7 TPR domain binding 3 photoreceptor connecting cilium 3 histone H4 acetylation 1 DNA duplex unwinding 14 regulation of mitotic cell cycle 1 protein peptidyl-prolyl isomerization 7 transferase activity, transferring acyl groups other than amino-acyl groups 3 platelet alpha granule lumen 3 histone ubiquitination 1 microtubule cytoskeleton 14 regulation of mitotic cell cycle spindle assembly checkpoint 1 receptor-mediated endocytosis 7 translation activator activity 3 preribosome, small subunit precursor 3 homeostatic process 1 nuclear speck 14 regulation of ruffle assembly 1 regulation of catalytic activity 7 tubulin binding 3 Prp19 complex 3 inflammatory response 1 nucleotidyltransferase activity 14 regulation of sequence-specific DNA binding transcription factor activity 1 regulation of protein stability 7 ubiquitin-specific protease binding 3 rough endoplasmic reticulum 3 Ino80 complex 1 protein dephosphorylation 14 regulation of spindle checkpoint 1 response to ethanol 7 vinculin binding 3 ruffle membrane 3 intermediate filament cytoskeleton 1 small GTPase mediated signal transduction 14 regulation of type I interferon-mediated signaling pathway 1 response to nutrient 7 1-phosphatidylinositol-3-kinase activity 2 site of double-strand break 3 intermediate filament cytoskeleton organization 1 cell-cell signaling 13 regulation of vascular wound healing 1 response to organic substance 7 2 iron, 2 sulfur cluster binding 2 small-subunit processome 3 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 1 cell cycle arrest 13 response to endoplasmic reticulum stress 1 response to oxidative stress 7 3-hydroxyisobutyrate dehydrogenase activity 2 small nuclear ribonucleoprotein complex 3 ion channel binding 1 cell division 13 response to ischemia 1 response to X-ray 7 4-alpha-glucanotransferase activity 2 smooth endoplasmic reticulum 3 JAK-STAT cascade 1 cellular metabolic process 13 response to lipopolysaccharide 1 sensory perception of sound 7 4-alpha-hydroxytetrahydrobiopterin dehydratase activity 2 striated muscle thin filament 3 kinase binding 1 chaperone binding 13 response to muramyl dipeptide 1 activation of cysteine-type endopeptidase activity involved in apoptotic process 6 4 iron, 4 sulfur cluster binding 2 SUN-KASH complex 3 lateral ventricle development 1 chromatin 13 response to UV 1 activation of signaling protein activity involved in unfolded protein response 6 5'-deoxyribose-5-phosphate lyase activity 2 supraspliceosomal complex 3 ligand-dependent nuclear receptor transcription coactivator activity 1 damaged DNA binding 13 response to X-ray 1 axonogenesis 6 6-phosphofructokinase activity 2 Swr1 complex 3 maintenance of DNA methylation 1 ER to Golgi vesicle-mediated transport 13 righting reflex 1 base-excision repair 6 7S RNA binding 2 transcription factor TFIID complex 3 melanocyte differentiation 1 eukaryotic 43S preinitiation complex 13 ripoptosome assembly involved in necroptotic process 1 cellular response to interleukin-4 6 acetyl-CoA C-acyltransferase activity 2 transcriptionally active chromatin 3 membrane organization 1 eukaryotic 48S preinitiation complex 13 RNA phosphodiester bond hydrolysis, exonucleolytic 1 cellular response to ionizing radiation 6 acetyl-CoA carboxylase activity 2 viral nucleocapsid 3 microtubule cytoskeleton organization 1 Fc-epsilon receptor signaling pathway 13 RNA splicing 1 chlorophyll biosynthetic process 6 acid-amino acid ligase activity 2 A band 2 midbrain development 1 formation of translation preinitiation complex 13 sensory perception of pain 1 DNA damage response, detection of DNA damage 6 acyl-CoA hydrolase activity 2 adherens junction 2 misfolded or incompletely synthesized protein catabolic process 1 methyltransferase activity 13 skeletal muscle atrophy 1 DNA damage response, signal transduction by p53 class mediator 6 adenyl nucleotide binding 2 apicolateral plasma membrane 2 mitochondrial matrix 1 microtubule-based movement 13 skeletal system development 1 double-strand break repair via homologous recombination 6 aldehyde dehydrogenase (NAD) activity 2 axolemma 2 mitochondrial membrane 1 microtubule motor activity 13 spermatogenesis 1 embryo development 6 alkylbase DNA N-glycosylase activity 2 catenin complex 2 mitochondrial outer membrane 1 nuclear chromatin 13 spliceosomal complex assembly 1 embryo implantation 6 alpha-catenin binding 2 CatSper complex 2 mitochondrion degradation 1 platelet activation 13 spliceosomal tri-snRNP complex assembly 1 energy reserve metabolic process 6 alpha-galactosidase activity 2 ciliary rootlet 2 mitochondrion organization 1 receptor binding 13 termination of RNA polymerase I transcription 1 glutamine metabolic process 6 alpha-L-fucosidase activity 2 clathrin adaptor complex 2 mitotic cell cycle checkpoint 1 regulation of cell cycle 13 tolerance induction to lipopolysaccharide 1 glutathione metabolic process 6 amino acid binding 2 clathrin coat 2 mRNA splicing, via spliceosome 1 sequence-specific DNA binding 13 transcription-coupled nucleotide-excision repair 1 hematopoietic progenitor cell differentiation 6 aminoacyl-tRNA editing activity 2 clathrin coat of coated pit 2 multicellular organismal development 1 single-stranded DNA binding 13 transcription elongation from RNA polymerase I promoter 1 hippo signaling 6 aminoacylase activity 2 clathrin coat of trans-Golgi network vesicle 2 muscle fiber development 1 stress fiber 13 transcription from RNA polymerase I promoter 1 histone deubiquitination 6 amylo-alpha-1,6-glucosidase activity 2 coated vesicle 2 muscle organ development 1 transporter activity 13 transcription from RNA polymerase II promoter 1 intrinsic apoptotic signaling pathway in response to DNA damage 6 apolipoprotein binding 2 condensed nuclear chromosome outer kinetochore 2 NAD+ ADP-ribosyltransferase activity 1 Wnt signaling pathway 13 transcription initiation from RNA polymerase I promoter 1 keratinocyte differentiation 6 ARF guanyl-nucleotide exchange factor activity 2 COPI vesicle coat 2 negative regulation of bone resorption 1 actin cytoskeleton organization 12 type I interferon signaling pathway 1 leukocyte migration 6 arginase activity 2 CRD-mediated mRNA stability complex 2 negative regulation of canonical Wnt signaling pathway 1 anatomical structure formation involved in morphogenesis 12 male gonad development 6 aspartate carbamoyltransferase activity 2 Cul2-RING ubiquitin ligase complex 2 negative regulation of CD40 signaling pathway 1 axon 12 methylation 6 aspartic-type endopeptidase activity 2 cuticular plate 2 negative regulation of cell death 1 cell body 12 mRNA 3'-end processing 6 ATP-dependent 5'-3' DNA helicase activity 2 cyclin-dependent protein kinase holoenzyme complex 2 negative regulation of cell proliferation 1 cellular component disassembly involved in execution phase of apoptosis 12 necroptotic process 6 ATPase activity, coupled 2 cytoplasmic dynein complex 2 negative regulation of chronic inflammatory response 1 chromosome segregation 12 negative regulation of mRNA splicing, via spliceosome 6 ATPase activity, coupled to transmembrane movement of substances 2 cytoplasmic ribonucleoprotein granule 2 negative regulation of cyclin-dependent protein serine/threonine kinase activity 1 double-stranded RNA binding 12 negative regulation of transforming growth factor beta receptor signaling pathway 6 calcium-dependent cysteine-type endopeptidase activity 2 DBIRD complex 2 negative regulation of double-strand break repair 1 glucose transport 12 neural tube closure 6 calcium channel activity 2 DNA-directed RNA polymerase III complex 2 negative regulation of endothelial cell apoptotic process 1 hexose transport 12 nuclear-transcribed mRNA poly(A) tail shortening 6 cAMP-dependent protein kinase regulator activity 2 DNA replication factor C complex 2 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors 1 mRNA transport 12 photosynthesis 6 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity 2 dynein complex 2 negative regulation of histone deacetylation 1 nuclear chromosome 12 plasma membrane organization 6 carboxy-lyase activity 2 ESC/E(Z) complex 2 negative regulation of histone H2A K63-linked ubiquitination 1 nuclease activity 12 positive regulation of protein catabolic process 6 catalase activity 2 eukaryotic translation initiation factor 2 complex 2 negative regulation of interleukin-1 beta production 1 phosphatase activity 12 positive regulation of protein phosphorylation 6 cell adhesion molecule binding 2 external side of plasma membrane 2 negative regulation of interleukin-2 production 1 phosphorylation 12 positive regulation of viral genome replication 6 centromeric DNA binding 2 female pronucleus 2 negative regulation of interleukin-8 production 1 regulation of glucose transport 12 positive regulation of viral transcription 6 chromatin DNA binding 2 gap junction 2 negative regulation of MAP kinase activity 1 sarcolemma 12 protein destabilization 6 chromo shadow domain binding 2 Golgi stack 2 negative regulation of mitotic anaphase-promoting complex activity 1 telomere maintenance 12 protein K11-linked deubiquitination 6 citrate (Si)-synthase activity 2 histone locus body 2 negative regulation of neuron apoptotic process 1 trans-Golgi network 12 protein targeting to Golgi 6 co-SMAD binding 2 histone pre-mRNA 3'end processing complex 2 negative regulation of NF-kappaB import into nucleus 1 transcription corepressor activity 12 proteolysis involved in cellular protein catabolic process 6 core promoter sequence-specific DNA binding 2 immunological synapse 2 negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway 1 transcription elongation from RNA polymerase II promoter 12 regulation of cell migration 6 cyclin-dependent protein serine/threonine kinase activity 2 intercellular bridge 2 negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway 1 transcription from RNA polymerase I promoter 12 regulation of cell shape 6 cysteine-type endopeptidase inhibitor activity 2 kinetochore microtubule 2 negative regulation of osteoclast proliferation 1 vesicle 12 regulation of circadian rhythm 6 D-alanine-D-alanine ligase activity 2 lysosomal lumen 2 negative regulation of phosphatidylinositol 3-kinase signaling 1 apical plasma membrane 11 regulation of protein catabolic process 6 deacetylase activity 2 macromolecular complex 2 negative regulation of protein localization to nucleus 1 Cajal body 11 regulation of protein kinase activity 6 dihydrolipoyllysine-residue acetyltransferase activity 2 male germ cell nucleus 2 negative regulation of protein processing 1 cell migration 11 respiratory electron transport chain 6 dihydroorotase activity 2 meiotic cohesin complex 2 negative regulation of protein targeting to membrane 1 cell surface 11 response to lipopolysaccharide 6 DNA-dependent protein kinase activity 2 membrane-bounded organelle 2 negative regulation of Ras GTPase activity 1 DNA helicase activity 11 rhythmic process 6 DNA (cytosine-5-)-methyltransferase activity 2 microvillus 2 negative regulation of Ras protein signal transduction 1 endoplasmic reticulum lumen 11 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 6 DNA replication origin binding 2 mitochondrial fatty acid beta-oxidation multienzyme complex 2 negative regulation of smooth muscle cell proliferation 1 epidermis development 11 termination of RNA polymerase II transcription 6 dolichyl-diphosphooligosaccharide-protein glycotransferase activity 2 mitochondrial inner membrane presequence translocase complex 2 negative regulation of T cell differentiation 1 Golgi membrane 11 viral life cycle 6 double-stranded RNA adenosine deaminase activity 2 mitotic spindle midzone 2 negative regulation of toll-like receptor 2 signaling pathway 1 lamellipodium 11 7-methylguanosine mRNA capping 5 double-stranded telomeric DNA binding 2 MLL5-L complex 2 negative regulation of toll-like receptor 3 signaling pathway 1 MCM complex 11 actin filament-based movement 5 endonuclease activity 2 mRNA cleavage and polyadenylation specificity factor complex 2 negative regulation of toll-like receptor 4 signaling pathway 1 motor activity 11 anatomical structure morphogenesis 5 endopeptidase inhibitor activity 2 MutSbeta complex 2 negative regulation of toll-like receptor 5 signaling pathway 1 muscle contraction 11 cell redox homeostasis 5 enoyl-CoA hydratase activity 2 myelin sheath 2 nervous system development 1 negative regulation of catalytic activity 11 cellular amino acid biosynthetic process 5 enzyme activator activity 2 myelin sheath abaxonal region 2 neuromuscular process 1 negative regulation of translation 11 cellular response to hydrogen peroxide 5 enzyme inhibitor activity 2 myosin filament 2 neuronal cell body 1 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 11 cellular response to insulin stimulus 5 epidermal growth factor receptor binding 2 nBAF complex 2 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 1 protein phosphatase type 2A complex 11 cellular response to oxidative stress 5 estrogen receptor binding 2 NLS-dependent protein nuclear import complex 2 nuclear-transcribed mRNA poly(A) tail shortening 1 protein ubiquitination involved in ubiquitin-dependent protein catabolic process 11 cellular response to starvation 5 eukaryotic initiation factor 4E binding 2 npBAF complex 2 nuclear chromatin 1 regulation of cell proliferation 11 chaperone-mediated protein complex assembly 5 fatty acid synthase activity 2 nuclear body 2 nuclear inclusion body 1 sulfur compound metabolic process 11 cholesterol metabolic process 5 ferrochelatase activity 2 nuclear exosome (RNase complex) 2 nuclear ubiquitin ligase complex 1 transcription initiation from RNA polymerase I promoter 11 cytoskeleton-dependent intracellular transport 5 FK506 binding 2 nuclear ubiquitin ligase complex 2 nuclease activity 1 transferase activity, transferring glycosyl groups 11 determination of adult lifespan 5 four-way junction DNA binding 2 nucleolar ribonuclease P complex 2 nucleic acid binding 1 translational elongation 11 DNA synthesis involved in DNA repair 5 fructose-bisphosphate aldolase activity 2 nucleosome 2 nucleobase-containing compound catabolic process 1 vacuole 11 ER-associated ubiquitin-dependent protein catabolic process 5 G-protein coupled receptor activity 2 nucleotide-excision repair complex 2 nucleotide-excision repair 1 aminoacyl-tRNA ligase activity 10 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 5 G-quadruplex DNA binding 2 PAN complex 2 nucleotidyltransferase activity 1 ATP-dependent DNA helicase activity 10 fatty acid beta-oxidation 5 G-quadruplex RNA binding 2 pericentriolar material 2 PAN complex 1 brain development 10 Fc-gamma receptor signaling pathway involved in phagocytosis 5 galactokinase activity 2 perikaryon 2 pathway-restricted SMAD protein phosphorylation 1 carbohydrate binding 10 G-protein coupled receptor signaling pathway 5 galactosylceramidase activity 2 phosphopyruvate hydratase complex 2 perinuclear region of cytoplasm 1 cell cortex 10 glycogen biosynthetic process 5 gamma-catenin binding 2 photoreceptor inner segment 2 poly(A)-specific ribonuclease activity 1 Cul3-RING ubiquitin ligase complex 10 glycogen catabolic process 5 gamma-glutamyltransferase activity 2 polar microtubule 2 polyubiquitin binding 1 endoplasmic reticulum unfolded protein response 10 Golgi organization 5 glucose-6-phosphate dehydrogenase activity 2 PR-DUB complex 2 positive regulation of cell cycle process 1 four-way junction helicase activity 10 histone H4 acetylation 5 glutamate-5-semialdehyde dehydrogenase activity 2 preribosome, large subunit precursor 2 positive regulation of cell proliferation 1 growth cone 10 intermediate filament organization 5 glutamate-tRNA ligase activity 2 presynaptic membrane 2 positive regulation of cellular protein catabolic process 1 GTP catabolic process 10 intracellular estrogen receptor signaling pathway 5 glutamate 5-kinase activity 2 pronucleus 2 positive regulation of DNA repair 1 isomerase activity 10 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 5 glutamine-tRNA ligase activity 2 proteasome regulatory particle, base subcomplex 2 positive regulation of endopeptidase activity 1 kinetochore 10 liver development 5 glutathione binding 2 protein kinase CK2 complex 2 positive regulation of extrinsic apoptotic signaling pathway 1 muscle organ development 10 locomotory behavior 5 glutathione peroxidase activity 2 proteinaceous extracellular matrix 2 positive regulation of hepatocyte proliferation 1 negative regulation of neuron apoptotic process 10 MAPK cascade 5 glycine-tRNA ligase activity 2 proton-transporting two-sector ATPase complex, catalytic domain 2 positive regulation of MDA-5 signaling pathway 1 nuclear matrix 10 mitotic cell cycle checkpoint 5 glycine hydroxymethyltransferase activity 2 recycling endosome 2 positive regulation of proteasomal ubiquitin-dependent protein catabolic process 1 nucleobase-containing small molecule metabolic process 10 mitotic sister chromatid segregation 5 glycogen debranching enzyme activity 2 retromer complex 2 positive regulation of protein catabolic process 1 phosphatidylinositol-mediated signaling 10 muscle fiber development 5 glycogen phosphorylase activity 2 SAGA-type complex 2 positive regulation of Rho GTPase activity 1 positive regulation of DNA repair 10 negative regulation of translational initiation 5 glycogen synthase activity, transferring glucose-1-phosphate 2 sarcoplasm 2 positive regulation of RIG-I signaling pathway 1 positive regulation of gene expression 10 negative regulation of type I interferon production 5 GMP synthase activity 2 small nucleolar ribonucleoprotein complex 2 positive regulation of skeletal muscle tissue development 1 positive regulation of I-kappaB kinase/NF-kappaB signaling 10 negative regulation of viral genome replication 5 GTPase activating protein binding 2 spindle midzone 2 positive regulation of translational elongation 1 positive regulation of translation 10 neurological system process 5 guanylate kinase activity 2 T-tubule 2 positive regulation of Wnt signaling pathway 1 positive regulation of type I interferon production 10 neuron projection development 5 H3 histone acetyltransferase activity 2 telomeric heterochromatin 2 PR-DUB complex 1 proteasome regulatory particle 10 nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway 5 H4 histone acetyltransferase activity 2 terminal bouton 2 proline-rich region binding 1 protein N-linked glycosylation via asparagine 10 peptide cross-linking 5 histone acetyltransferase activity (H4-K16 specific) 2 trans-Golgi network membrane 2 protease binding 1 protein N-terminus binding 10 peptidyl-serine phosphorylation 5 histone acetyltransferase activity (H4-K5 specific) 2 transcription factor TFTC complex 2 proteasome regulatory particle 1 protein phosphatase binding 10 platelet aggregation 5 histone acetyltransferase activity (H4-K8 specific) 2 U12-type spliceosomal complex 2 proteasome regulatory particle, lid subcomplex 1 protein stabilization 10 positive regulation of cell growth 5 histone demethylase activity (H3-dimethyl-K4 specific) 2 U2-type spliceosomal complex 2 protein C-terminus binding 1 regulation of translation 10 positive regulation of G1/S transition of mitotic cell cycle 5 histone demethylase activity (H3-K36 specific) 2 U4/U6 snRNP 2 protein catabolic process 1 response to hypoxia 10 positive regulation of intrinsic apoptotic signaling pathway 5 histone demethylase activity (H3-K4 specific) 2 unconventional myosin complex 2 protein deneddylation 1 response to unfolded protein 10 positive regulation of mitotic cell cycle 5 histone demethylase activity (H3-monomethyl-K4 specific) 2 uropod 2 protein desumoylation 1 response to UV 10 post-Golgi vesicle-mediated transport 5 histone kinase activity (H3-T11 specific) 2 VCB complex 2 protein deubiquitination involved in ubiquitin-dependent protein catabolic process 1 response to virus 10 protein autophosphorylation 5 histone methyltransferase activity 2 WASH complex 2 protein homodimerization activity 1 RNA splicing, via transesterification reactions 10 protein heterooligomerization 5 histone methyltransferase activity (H3-R17 specific) 2 XPC complex 2 protein homotetramerization 1 single organismal cell-cell adhesion 10 protein import into nucleus 5 Hsp70 protein binding 2 90S preribosome 1 protein K27-linked deubiquitination 1 SRP-dependent cotranslational protein targeting to membrane 10 protein K63-linked ubiquitination 5 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 2 acrosomal membrane 1 protein K48-linked ubiquitination 1 toxin transport 10 protein localization 5 hydrolase activity, acting on ester bonds 2 actomyosin contractile ring 1 protein localization to cell surface 1 transcription initiation from RNA polymerase II promoter 10 protein refolding 5 hydrolase activity, hydrolyzing O-glycosyl compounds 2 alpha DNA polymerase:primase complex 1 protein maturation 1 transcription regulatory region DNA binding 10 protein targeting to mitochondrion 5 insulin-like growth factor receptor binding 2 aminoacyl-tRNA synthetase multienzyme complex 1 protein oligomerization 1 tRNA processing 10 purine nucleobase metabolic process 5 integrin binding 2 AMP-activated protein kinase complex 1 protein self-association 1 ubiquitin binding 10 pyruvate metabolic process 5 ion channel inhibitor activity 2 anchored component of external side of plasma membrane 1 Ras protein signal transduction 1 'de novo' posttranslational protein folding 9 regulation of cytoskeleton organization 5 isoleucine-tRNA ligase activity 2 apical dendrite 1 regulation of catalytic activity 1 autophagy 9 regulation of double-strand break repair via homologous recombination 5 keratin filament binding 2 ASAP complex 1 regulation of cell-substrate adhesion 1 cell morphogenesis 9 regulation of RNA biosynthetic process 5 ketol-acid reductoisomerase activity 2 ATP-binding cassette (ABC) transporter complex 1 regulation of cell growth 1 chaperone-mediated protein folding 9 response to heat 5 kinetochore binding 2 autophagic vacuole 1 regulation of cell migration 1 cullin deneddylation 9 response to organic cyclic compound 5 L-glutamate transmembrane transporter activity 2 BAF-type complex 1 regulation of cell morphogenesis 1 cytoplasmic vesicle 9 response to toxic substance 5 ligase activity, forming aminoacyl-tRNA and related compounds 2 basal cortex 1 regulation of cell proliferation 1 dendritic spine 9 retina development in camera-type eye 5 lipopolysaccharide binding 2 basal lamina 1 regulation of cellular response to hypoxia 1 DNA-directed RNA polymerase activity 9 retrograde transport, endosome to Golgi 5 long-chain-3-hydroxyacyl-CoA dehydrogenase activity 2 basal part of cell 1 regulation of chemotaxis 1 DNA strand elongation involved in DNA replication 9 RNA phosphodiester bond hydrolysis, exonucleolytic 5 Lys63-specific deubiquitinase activity 2 beta-catenin destruction complex 1 regulation of DNA repair 1 double-stranded DNA binding 9 sarcomere organization 5 lysine-acetylated histone binding 2 box C/D snoRNP complex 1 regulation of intrinsic apoptotic signaling pathway 1 endocytosis 9 skin development 5 mannose binding 2 brush border 1 regulation of JNK cascade 1 glycolytic process 9 spliceosomal complex assembly 5 MDM2/MDM4 family protein binding 2 brush border membrane 1 regulation of microtubule cytoskeleton organization 1 histone deacetylase binding 9 tricarboxylic acid cycle 5 mediator complex binding 2 calcium channel complex 1 regulation of mitotic cell cycle 1 iron ion binding 9 vacuolar transport 5 medium-chain-acyl-CoA dehydrogenase activity 2 cAMP-dependent protein kinase complex 1 regulation of mitotic cell cycle spindle assembly checkpoint 1 kinesin complex 9 viral transcription 5 metalloexopeptidase activity 2 Cdc48p-Npl4p-Ufd1p AAA ATPase complex 1 regulation of ruffle assembly 1 mitochondrial small ribosomal subunit 9 vitamin metabolic process 5 methionine-tRNA ligase activity 2 cell-substrate junction 1 regulation of sequence-specific DNA binding transcription factor activity 1 myosin complex 9 water-soluble vitamin metabolic process 5 MHC class I protein binding 2 centriolar satellite 1 regulation of spindle checkpoint 1 negative regulation of cell growth 9 actin cytoskeleton reorganization 4 microtubule plus-end binding 2 centrosomal corona 1 regulation of type I interferon-mediated signaling pathway 1 negative regulation of NF-kappaB transcription factor activity 9 actin filament bundle assembly 4 mitochondrial light strand promoter anti-sense binding 2 chloride channel complex 1 regulation of vascular wound healing 1 omega peptidase activity 9 activation of MAPK activity 4 MutLalpha complex binding 2 chromatin silencing complex 1 response to endoplasmic reticulum stress 1 polyubiquitin binding 9 activation of MAPKK activity 4 myosin binding 2 chromatoid body 1 response to ischemia 1 positive regulation of cell migration 9 adherens junction organization 4 NAD-dependent histone deacetylase activity 2 chromosome, centromeric core domain 1 response to lipopolysaccharide 1 positive regulation of GTPase activity 9 angiogenesis 4 NAD-dependent histone deacetylase activity (H3-K9 specific) 2 ciliary base 1 response to muramyl dipeptide 1 positive regulation of proteasomal ubiquitin-dependent protein catabolic process 9 apical junction assembly 4 NAD-dependent protein deacetylase activity 2 clathrin complex 1 response to UV 1 post-translational protein modification 9 auditory receptor cell stereocilium organization 4 NAD(P)H oxidase activity 2 cohesin complex 1 response to X-ray 1 protein catabolic process 9 B cell differentiation 4 NADH dehydrogenase (ubiquinone) activity 2 collagen trimer 1 righting reflex 1 protein dimerization activity 9 branched-chain amino acid catabolic process 4 NEDD8-specific protease activity 2 collagen type IV trimer 1 ripoptosome assembly involved in necroptotic process 1 protein homotetramerization 9 cardiac muscle contraction 4 neurexin family protein binding 2 condensed chromosome kinetochore 1 RNA phosphodiester bond hydrolysis, exonucleolytic 1 pyridoxal phosphate binding 9 cell aging 4 nucleoside diphosphate kinase activity 2 condensed chromosome outer kinetochore 1 RNA polymerase transcription factor SL1 complex 1 Ras protein signal transduction 9 cell growth 4 oxidized purine DNA binding 2 condensed chromosome, centromeric region 1 RNA splicing 1 receptor activity 9 cellular protein complex assembly 4 oxidoreductase activity, acting on NAD(P)H 2 contractile ring 1 SAGA-type complex 1 regulation of gene expression 9 cellular response to epidermal growth factor stimulus 4 oxidoreductase activity, acting on peroxide as acceptor 2 cortical microtubule cytoskeleton 1 SAGA complex 1 response to ionizing radiation 9 cellular response to heat 4 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 2 Cul5-RING ubiquitin ligase complex 1 sensory perception of pain 1 ribosome biogenesis 9 cellular response to organic substance 4 oxidoreductase activity, acting on the CH-CH group of donors 2 Cul7-RING ubiquitin ligase complex 1 SH3 domain binding 1 spliceosomal tri-snRNP complex assembly 9 cellular response to UV 4 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 2 cyclin-dependent protein kinase activating kinase holoenzyme complex 1 skeletal muscle atrophy 1 substantia nigra development 9 centrosome localization 4 oxoglutarate dehydrogenase (succinyl-transferring) activity 2 cytoplasmic side of endoplasmic reticulum membrane 1 skeletal system development 1 synapse 9 circadian regulation of gene expression 4 peptide binding 2 cytosolic ribosome 1 SMAD binding 1 synaptic transmission 9 cytokinesis 4 phosphatidylinositol-4,5-bisphosphate binding 2 delta DNA polymerase complex 1 spermatogenesis 1 termination of RNA polymerase I transcription 9 cytoplasmic mRNA processing body assembly 4 phosphatidylinositol 3-kinase binding 2 dendritic shaft 1 spliceosomal complex 1 transcription elongation from RNA polymerase I promoter 9 DNA damage checkpoint 4 phosphatidylinositol binding 2 dense core granule 1 spliceosomal complex assembly 1 transforming growth factor beta receptor signaling pathway 9 DNA unwinding involved in DNA replication 4 phospholipase A2 inhibitor activity 2 DNA-dependent protein kinase-DNA ligase 4 complex 1 spliceosomal tri-snRNP complex assembly 1 ubiquitin ligase complex 9 epithelial cell differentiation 4 phospholipase binding 2 DNA polymerase III complex 1 SUMO-specific isopeptidase activity 1 ADP binding 8 establishment or maintenance of cell polarity 4 phosphopyruvate hydratase activity 2 ectoplasm 1 synapse 1 apical part of cell 8 forebrain development 4 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity 2 endoplasmic reticulum exit site 1 synaptic vesicle 1 ATP biosynthetic process 8 gastrulation 4 phosphoribosylformylglycinamidine synthase activity 2 ER-mitochondrion membrane contact site 1 termination of RNA polymerase I transcription 1 basolateral plasma membrane 8 gluconeogenesis 4 phosphorylase kinase regulator activity 2 euchromatin 1 tolerance induction to lipopolysaccharide 1 binding of sperm to zona pellucida 8 glycogen metabolic process 4 phosphoserine binding 2 eukaryotic translation elongation factor 1 complex 1 transcription-coupled nucleotide-excision repair 1 cell junction assembly 8 growth 4 phosphotyrosine binding 2 eukaryotic translation initiation factor 2B complex 1 transcription elongation from RNA polymerase I promoter 1 cellular lipid metabolic process 8 histone acetylation 4 plus-end-directed microtubule motor activity 2 exocyst 1 transcription from RNA polymerase I promoter 1 cellular protein localization 8 histone H2A monoubiquitination 4 poly(A)-specific ribonuclease activity 2 extrinsic component of plasma membrane 1 transcription from RNA polymerase II promoter 1 cellular response to hypoxia 8 histone H3-K4 demethylation 4 procollagen-lysine 5-dioxygenase activity 2 F-actin capping protein complex 1 transcription initiation from RNA polymerase I promoter 1 chaperonin-containing T-complex 8 histone H3 deacetylation 4 procollagen glucosyltransferase activity 2 fibrillar center 1 transferase activity, transferring acyl groups 1 cilium 8 homeostasis of number of cells 4 profilin binding 2 filamentous actin 1 transferase activity, transferring glycosyl groups 1 cullin-RING ubiquitin ligase complex 8 immune response 4 proline-tRNA ligase activity 2 gamma-catenin-TCF7L2 complex 1 transforming growth factor beta receptor binding 1 cytoplasmic stress granule 8 integrin-mediated signaling pathway 4 protein-arginine omega-N asymmetric methyltransferase activity 2 glucosidase II complex 1 translation initiation factor binding 1 defense response to virus 8 intermediate filament cytoskeleton organization 4 protein-glutamine gamma-glutamyltransferase activity 2 glycogen granule 1 tRNA guanylyltransferase activity 1 dephosphorylation 8 intracellular transport 4 protein anchor 2 Golgi cisterna 1 type I interferon signaling pathway 1 double-strand break repair via nonhomologous end joining 8 isotype switching 4 protein complex scaffold 2 granular component 1 ubiquitin-protein transferase activity 1 early endosome 8 keratinization 4 protein deacetylase activity 2 Grb2-EGFR complex 1 ubiquitin ligase complex 1 extracellular matrix 8 kidney development 4 protein disulfide isomerase activity 2 hemidesmosome 1 VCB complex 1 G2 DNA damage checkpoint 8 misfolded or incompletely synthesized protein catabolic process 4 protein disulfide oxidoreductase activity 2 heterotrimeric G-protein complex 1 inflammatory response 8 mismatch repair 4 protein kinase regulator activity 2 high-density lipoprotein particle 1 ion channel binding 8 mitotic metaphase plate congression 4 protein methyltransferase activity 2 histone deacetylase complex 1 mitotic spindle assembly checkpoint 8 mitotic nuclear envelope reassembly 4 protein O-GlcNAc transferase activity 2 Hrd1p ubiquitin ligase complex 1 mRNA 3'-UTR binding 8 monoubiquitinated histone H2A deubiquitination 4 protein phosphatase inhibitor activity 2 integral component of lumenal side of endoplasmic reticulum membrane 1 NAD binding 8 monoubiquitinated protein deubiquitination 4 protein self-association 2 integrin complex 1 negative regulation of protein ubiquitination 8 mRNA polyadenylation 4 protein serine/threonine kinase activator activity 2 interstitial matrix 1 nervous system development 8 muscle cell cellular homeostasis 4 proton-transporting ATPase activity, rotational mechanism 2 isoamylase complex 1 Notch signaling pathway 8 negative regulation of canonical Wnt signaling pathway 4 pyridoxal kinase activity 2 lamellipodium membrane 1 nuclear inclusion body 8 negative regulation of DNA recombination 4 R-SMAD binding 2 large ribosomal subunit 1 nucleosome assembly 8 negative regulation of epidermal growth factor receptor signaling pathway 4 Ras GTPase activator activity 2 lateral element 1 p53 binding 8 negative regulation of fat cell differentiation 4 rDNA binding 2 lipopolysaccharide receptor complex 1 positive regulation of NF-kappaB transcription factor activity 8 negative regulation of gene expression 4 retinoic acid receptor binding 2 low-density lipoprotein particle 1 postsynaptic membrane 8 negative regulation of I-kappaB kinase/NF-kappaB signaling 4 ribonuclease activity 2 macropinosome 1 protease binding 8 negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway 4 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor 2 male pronucleus 1 proteasome core complex 8 negative regulation of phosphatase activity 4 ribonucleoside binding 2 membrane-bounded vesicle 1 protein homooligomerization 8 negative regulation of protein kinase activity 4 ribose-5-phosphate isomerase activity 2 MHC class I protein complex 1 protein monoubiquitination 8 negative regulation of skeletal muscle tissue development 4 RNA polymerase binding 2 microtubule bundle 1 protein transporter activity 8 negative regulation of translation involved in gene silencing by miRNA 4 RNA polymerase II activity 2 mitochondrial alpha-ketoglutarate dehydrogenase complex 1 regulation of alternative mRNA splicing, via spliceosome 8 nuclear-transcribed mRNA catabolic process 4 RNA polymerase II carboxy-terminal domain kinase activity 2 mitochondrial proton-transporting ATP synthase, catalytic core 1 retina homeostasis 8 nuclear migration along microfilament 4 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription 2 mitochondrial pyruvate dehydrogenase complex 1 ribosome binding 8 nuclear pore organization 4 RNA polymerase II core promoter sequence-specific DNA binding 2 mitochondrial respiratory chain complex I 1 SCF ubiquitin ligase complex 8 nucleic acid phosphodiester bond hydrolysis 4 RNA polymerase II distal enhancer sequence-specific DNA binding 2 motile primary cilium 1 spindle 8 nucleobase-containing compound metabolic process 4 RNA polymerase II regulatory region sequence-specific DNA binding 2 multivesicular body 1 transcription-coupled nucleotide-excision repair 8 nucleobase-containing small molecule interconversion 4 RNA polymerase II repressing transcription factor binding 2 muscle thin filament tropomyosin 1 transcription cofactor activity 8 nucleotide-binding oligomerization domain containing signaling pathway 4 RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription 2 Myb complex 1 translational termination 8 organ regeneration 4 RNA polymerase III activity 2 myelin sheath adaxonal region 1 zona pellucida receptor complex 8 peptidyl-tyrosine dephosphorylation 4 rRNA (adenine-N6,N6-)-dimethyltransferase activity 2 NatA complex 1 ATP-dependent RNA helicase activity 7 phospholipid metabolic process 4 S-adenosylmethionine-dependent methyltransferase activity 2 neuron projection terminus 1 blood microparticle 7 positive regulation of catalytic activity 4 serine-tRNA ligase activity 2 nonmotile primary cilium 1 cellular component movement 7 positive regulation of cholesterol efflux 4 single guanine insertion binding 2 nuclear cap binding complex 1 chromatin modification 7 positive regulation of interferon-alpha production 4 single thymine insertion binding 2 nuclear cyclin-dependent protein kinase holoenzyme complex 1 chromatin remodeling 7 positive regulation of protein import into nucleus 4 siRNA binding 2 nuclear lamina 1 chromosome, centromeric region 7 positive regulation of protein serine/threonine kinase activity 4 sodium ion binding 2 nuclear lumen 1 COPII vesicle coating 7 positive regulation of Wnt signaling pathway 4 steroid hormone binding 2 nuclear meiotic cohesin complex 1 cortical cytoskeleton 7 protein autoubiquitination 4 succinate-CoA ligase (GDP-forming) activity 2 nuclear origin of replication recognition complex 1 cytoplasmic vesicle membrane 7 protein export from nucleus 4 superoxide dismutase activity 2 nuclear outer membrane 1 desmosome 7 protein localization to nucleus 4 thyroid hormone receptor binding 2 nuclear outer membrane-endoplasmic reticulum membrane network 1 DNA replication initiation 7 protein oligomerization 4 toxic substance binding 2 nuclear pericentric heterochromatin 1 eukaryotic translation initiation factor 3 complex, eIF3m 7 protein targeting to plasma membrane 4 transcription regulatory region sequence-specific DNA binding 2 nuclear proteasome complex 1 eukaryotic translation initiation factor 4F complex 7 protein tetramerization 4 translation release factor activity 2 oligosaccharyltransferase complex 1 glycoprotein binding 7 proton transport 4 transmembrane receptor protein tyrosine phosphatase activity 2 oxoglutarate dehydrogenase complex 1 heart development 7 purine ribonucleoside monophosphate biosynthetic process 4 tumor necrosis factor receptor binding 2 Parkin-FBXW7-Cul1 ubiquitin ligase complex 1 heat shock protein binding 7 reciprocal meiotic recombination 4 UDP-glucose:glycoprotein glucosyltransferase activity 2 PCAF complex 1 histone acetyltransferase activity 7 regulation of blood pressure 4 valine-tRNA ligase activity 2 PeBoW complex 1 inclusion body 7 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion 4 voltage-gated anion channel activity 2 pericentric heterochromatin 1 insulin receptor signaling pathway 7 regulation of growth 4 [acyl-carrier-protein] S-acetyltransferase activity 1 phagocytic cup 1 intercalated disc 7 regulation of mitotic cell cycle 4 [acyl-carrier-protein] S-malonyltransferase activity 1 phagocytic vesicle 1 lateral plasma membrane 7 regulation of proteasomal protein catabolic process 4 1-phosphatidylinositol-4-phosphate 3-kinase activity 1 phosphatidylinositol 3-kinase complex 1 lipid particle 7 regulation of small GTPase mediated signal transduction 4 1-phosphatidylinositol binding 1 phosphatidylinositol 3-kinase complex, class IB 1 microtubule cytoskeleton organization 7 regulation of the force of heart contraction 4 17-beta-hydroxysteroid dehydrogenase (NAD+) activity 1 photoreceptor outer segment membrane 1 mitochondrial intermembrane space 7 response to calcium ion 4 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity 1 platelet dense tubular network membrane 1 mitotic cytokinesis 7 response to estradiol 4 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity 1 podosome 1 mitotic spindle organization 7 response to estrogen 4 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity 1 polysomal ribosome 1 multicellular organism growth 7 response to hormone 4 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity 1 pore complex 1 muscle filament sliding 7 response to insulin 4 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity 1 prefoldin complex 1 myosin II complex 7 response to zinc ion 4 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity 1 presynaptic cytoskeletal matrix assembled at active zones 1 negative regulation of endopeptidase activity 7 RNA phosphodiester bond hydrolysis 4 3-oxoacyl-[acyl-carrier-protein] synthase activity 1 procollagen-proline 4-dioxygenase complex 1 neuron migration 7 rRNA methylation 4 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity 1 proteasome activator complex 1 nuclear heterochromatin 7 skeletal muscle tissue development 4 6-phosphofructo-2-kinase activity 1 proteasome regulatory particle, lid subcomplex 1 one-carbon metabolic process 7 somatic hypermutation of immunoglobulin genes 4 acetyl-CoA C-acetyltransferase activity 1 protein-DNA complex 1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors 7 somatic recombination of immunoglobulin gene segments 4 acetylcholine receptor binding 1 protein phosphatase 4 complex 1 pentose-phosphate shunt 7 sphingolipid metabolic process 4 acetylglucosaminyltransferase activity 1 protein phosphatase type 1 complex 1 peptidyl-prolyl cis-trans isomerase activity 7 toll-like receptor signaling pathway 4 acetyltransferase activity 1 proton-transporting ATP synthase complex, catalytic core F(1) 1 peptidyl-threonine phosphorylation 7 transcription from RNA polymerase III promoter 4 actin monomer binding 1 pyruvate dehydrogenase complex 1 phospholipid binding 7 tRNA aminoacylation 4 actinin binding 1 rDNA heterochromatin 1 platelet degranulation 7 V(D)J recombination 4 activating transcription factor binding 1 respiratory chain 1 positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway 7 viral entry into host cell 4 adenosine deaminase activity 1 ribbon synapse 1 protein kinase C binding 7 wound healing 4 adenosine receptor binding 1 ribonuclease MRP complex 1 protein peptidyl-prolyl isomerization 7 acetyl-CoA metabolic process 3 adenylate cyclase binding 1 RNA polymerase I core factor complex 1 protein phosphatase type 2A regulator activity 7 actin crosslink formation 3 ADP-ribosylation factor binding 1 RNA polymerase I transcription factor complex 1 protein serine/threonine phosphatase activity 7 actin filament capping 3 aldehyde dehydrogenase [NAD(P)+] activity 1 RNA polymerase transcription factor SL1 complex 1 receptor-mediated endocytosis 7 actin filament organization 3 alpha-2A adrenergic receptor binding 1 SAGA complex 1 regulation of catalytic activity 7 activation of phospholipase C activity 3 alpha-tubulin binding 1 sarcoplasmic reticulum membrane 1 regulation of protein stability 7 actomyosin structure organization 3 amino acid transmembrane transporter activity 1 Scrib-APC-beta-catenin complex 1 response to ethanol 7 adult heart development 3 ammonia-lyase activity 1 Set1C/COMPASS complex 1 response to nutrient 7 adult locomotory behavior 3 AMP binding 1 signal recognition particle 1 response to organic substance 7 androgen receptor signaling pathway 3 anaphase-promoting complex binding 1 signal recognition particle receptor complex 1 response to oxidative stress 7 angiotensin maturation 3 androgen receptor binding 1 signal recognition particle, endoplasmic reticulum targeting 1 response to X-ray 7 aorta morphogenesis 3 angiostatin binding 1 Sin3 complex 1 sarcomere 7 apoptotic cell clearance 3 ankyrin repeat binding 1 slit diaphragm 1 sensory perception of sound 7 ATP hydrolysis coupled proton transport 3 annealing helicase activity 1 smooth muscle contractile fiber 1 spindle pole 7 ATP metabolic process 3 antigen binding 1 spectrin-associated cytoskeleton 1 structural constituent of muscle 7 ATP synthesis coupled proton transport 3 arachidonic acid binding 1 sperm fibrous sheath 1 transcription factor complex 7 bile acid metabolic process 3 asparagine synthase (glutamine-hydrolyzing) activity 1 sperm principal piece 1 3-hydroxyacyl-CoA dehydrogenase activity 6 bone development 3 aspartate-tRNA ligase activity 1 spindle pole centrosome 1 actin filament 6 camera-type eye development 3 aspartate binding 1 succinate-CoA ligase complex (GDP-forming) 1 activation of cysteine-type endopeptidase activity involved in apoptotic process 6 cardiac myofibril assembly 3 ATP-dependent 3'-5' DNA helicase activity 1 SWI/SNF complex 1 activation of signaling protein activity involved in unfolded protein response 6 cell-cell junction assembly 3 ATPase binding 1 SWI/SNF superfamily-type complex 1 axonogenesis 6 cell-cell junction organization 3 AU-rich element binding 1 synaptonemal complex 1 base-excision repair 6 cell surface receptor signaling pathway 3 betaine-aldehyde dehydrogenase activity 1 syntrophin complex 1 BRCA1-A complex 6 cellular aldehyde metabolic process 3 bHLH transcription factor binding 1 TCTN-B9D complex 1 cell-cell adherens junction 6 cellular carbohydrate metabolic process 3 bile acid binding 1 TORC1 complex 1 cell periphery 6 cellular response to amino acid stimulus 3 biotin carboxylase activity 1 trans-Golgi network transport vesicle 1 cellular response to interleukin-4 6 cellular response to calcium ion 3 C2H2 zinc finger domain binding 1 transcription factor TFIIA complex 1 cellular response to ionizing radiation 6 cellular response to interferon-gamma 3 calcium-release channel activity 1 transcriptional repressor complex 1 chlorophyll biosynthetic process 6 cellular response to mechanical stimulus 3 calcium ion transmembrane transporter activity 1 tRNA (m1A) methyltransferase complex 1 chromosome, telomeric region 6 cellular response to misfolded protein 3 calcium:sodium antiporter activity 1 U1 snRNP 1 clathrin-coated vesicle 6 cellular response to organic cyclic compound 3 cAMP-dependent protein kinase inhibitor activity 1 U2 snRNP 1 cleavage furrow 6 cellular response to steroid hormone stimulus 3 cAMP binding 1 U4 snRNP 1 condensed nuclear chromosome 6 CENP-A containing nucleosome assembly 3 carbonate dehydratase activity 1 U4atac snRNP 1 COPII vesicle coat 6 central nervous system development 3 carboxyl- or carbamoyltransferase activity 1 UBC13-MMS2 complex 1 costamere 6 centrosome duplication 3 carboxylic acid binding 1 UBC13-UEV1A complex 1 dendrite 6 chromatin-mediated maintenance of transcription 3 carboxylic ester hydrolase activity 1 ubiquitin conjugating enzyme complex 1 DNA-directed RNA polymerase I complex 6 cilium assembly 3 carboxypeptidase activity 1 vesicle coat 1 DNA damage response, detection of DNA damage 6 cilium morphogenesis 3 cation-transporting ATPase activity 1 vesicle membrane 1 DNA damage response, signal transduction by p53 class mediator 6 circadian rhythm 3 cation binding 1 double-strand break repair via homologous recombination 6 cytokine production 3 chloride channel activity 1 electron carrier activity 6 cytoskeletal anchoring at nuclear membrane 3 cholate 7-alpha-dehydrogenase activity 1 embryo development 6 DNA-templated transcription, initiation 3 choloyl-CoA hydrolase activity 1 embryo implantation 6 DNA methylation 3 clathrin light chain binding 1 energy reserve metabolic process 6 DNA replication-independent nucleosome assembly 3 coenzyme binding 1 filopodium 6 embryonic organ development 3 cofactor binding 1 glutamine metabolic process 6 endosomal transport 3 creatine kinase activity 1 glutathione metabolic process 6 epithelial to mesenchymal transition 3 CTP binding 1 hematopoietic progenitor cell differentiation 6 erythrocyte differentiation 3 CXCR chemokine receptor binding 1 heme binding 6 establishment of protein localization 3 cyclic nucleotide binding 1 hippo signaling 6 exocytosis 3 cysteine-type endopeptidase activator activity involved in apoptotic process 1 histone deubiquitination 6 fatty acid biosynthetic process 3 dATP binding 1 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 6 fatty acid homeostasis 3 death receptor binding 1 hydrolase activity, acting on glycosyl bonds 6 ferrous iron transport 3 delta-catenin binding 1 intrinsic apoptotic signaling pathway in response to DNA damage 6 formation of cytoplasmic translation initiation complex 3 deoxyribonuclease activity 1 keratinocyte differentiation 6 gene silencing by RNA 3 deubiquitinase activator activity 1 leukocyte migration 6 glucocorticoid receptor signaling pathway 3 dGTP binding 1 magnesium chelatase activity 6 hair cycle 3 dGTPase activity 1 male gonad development 6 hemidesmosome assembly 3 dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity 1 metallopeptidase activity 6 hepatocyte apoptotic process 3 dinucleotide insertion or deletion binding 1 methylation 6 hippocampus development 3 dinucleotide repeat insertion binding 1 mRNA 3'-end processing 6 histone H2A acetylation 3 dioxygenase activity 1 necroptotic process 6 histone H2A K63-linked deubiquitination 3 disulfide oxidoreductase activity 1 negative regulation of mRNA splicing, via spliceosome 6 histone H3 acetylation 3 DNA-3-methyladenine glycosylase activity 1 negative regulation of transforming growth factor beta receptor signaling pathway 6 histone ubiquitination 3 DNA-3-methylguanine glycosylase activity 1 neural tube closure 6 homophilic cell adhesion via plasma membrane adhesion molecules 3 DNA-7-methyladenine glycosylase activity 1 nuclear-transcribed mRNA poly(A) tail shortening 6 hydrogen peroxide catabolic process 3 DNA-7-methylguanine glycosylase activity 1 nuclear euchromatin 6 inactivation of MAPK activity 3 DNA-methyltransferase activity 1 nuclear pore nuclear basket 6 intrinsic apoptotic signaling pathway by p53 class mediator 3 DNA binding, bending 1 nucleocytoplasmic transporter activity 6 ion transmembrane transport 3 DNA clamp loader activity 1 peroxisomal membrane 6 ion transport 3 DNA polymerase binding 1 phosphoprotein binding 6 L-proline biosynthetic process 3 DNA translocase activity 1 phosphoprotein phosphatase activity 6 lateral ventricle development 3 double-strand/single-strand DNA junction binding 1 photosynthesis 6 lipid transport 3 double-stranded DNA-dependent ATPase activity 1 plasma membrane organization 6 lipoprotein metabolic process 3 dynein binding 1 polysome 6 lung development 3 dynein complex binding 1 positive regulation of protein catabolic process 6 maintenance of DNA methylation 3 dynein light intermediate chain binding 1 positive regulation of protein phosphorylation 6 maternal process involved in female pregnancy 3 dystroglycan binding 1 positive regulation of viral genome replication 6 meiotic nuclear division 3 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity 1 positive regulation of viral transcription 6 miRNA loading onto RISC involved in gene silencing by miRNA 3 enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity 1 protein destabilization 6 mitochondrial ATP synthesis coupled proton transport 3 enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity 1 protein K11-linked deubiquitination 6 mitochondrial fusion 3 eukaryotic initiation factor 4G binding 1 protein targeting to Golgi 6 mitochondrion degradation 3 eukaryotic translation initiation factor 2alpha kinase activity 1 proteolysis involved in cellular protein catabolic process 6 mitotic sister chromatid cohesion 3 exonuclease activity 1 regulation of cell migration 6 mitotic spindle checkpoint 3 exoribonuclease activity 1 regulation of cell shape 6 morphogenesis of an epithelium 3 extracellular matrix structural constituent 1 regulation of circadian rhythm 6 morphogenesis of embryonic epithelium 3 FAD binding 1 regulation of protein catabolic process 6 mRNA cleavage 3 fatty acid binding 1 regulation of protein kinase activity 6 muscle cell differentiation 3 Fc-gamma receptor I complex binding 1 respiratory electron transport chain 6 MyD88-dependent toll-like receptor signaling pathway 3 ferrous iron binding 1 response to lipopolysaccharide 6 negative regulation of cyclin-dependent protein serine/threonine kinase activity 3 fibronectin binding 1 rhythmic process 6 negative regulation of DNA replication 3 frizzled binding 1 ribonucleoprotein complex binding 6 negative regulation of double-strand break repair 3 fructose binding 1 RNA cap binding 6 negative regulation of extrinsic apoptotic signaling pathway 3 fucose binding 1 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 6 negative regulation of GTPase activity 3 fucosidase activity 1 secretory granule 6 negative regulation of histone H2A K63-linked ubiquitination 3 G-protein alpha-subunit binding 1 structural constituent of epidermis 6 negative regulation of MAP kinase activity 3 G-protein beta-subunit binding 1 synaptic vesicle 6 negative regulation of neuron death 3 GABA receptor binding 1 termination of RNA polymerase II transcription 6 negative regulation of nitric-oxide synthase activity 3 GAF domain binding 1 transcription elongation factor complex 6 negative regulation of proteasomal ubiquitin-dependent protein catabolic process 3 galactose binding 1 U5 snRNP 6 negative regulation of protein binding 3 galactoside binding 1 viral life cycle 6 negative regulation of protein catabolic process 3 GDP binding 1 7-methylguanosine mRNA capping 5 negative regulation of protein dephosphorylation 3 glucan 1,3-alpha-glucosidase activity 1 acrosomal vesicle 5 negative regulation of protein kinase activity by regulation of protein phosphorylation 3 glucocorticoid receptor binding 1 actin-dependent ATPase activity 5 negative regulation of protein kinase B signaling 3 glutaminyl-peptide cyclotransferase activity 1 actin filament-based movement 5 negative regulation of protein phosphorylation 3 glutathione hydrolase activity 1 anatomical structure morphogenesis 5 negative regulation of sequence-specific DNA binding transcription factor activity 3 glycine dehydrogenase (decarboxylating) activity 1 ankyrin binding 5 negative regulation of Wnt signaling pathway 3 glycolipid binding 1 BRISC complex 5 neural tube development 3 GMP synthase (glutamine-hydrolyzing) activity 1 cadherin binding 5 neuromuscular process controlling balance 3 GTPase binding 1 cell leading edge 5 neuron differentiation 3 guanyl nucleotide binding 1 cell redox homeostasis 5 nitric oxide metabolic process 3 heteroduplex DNA loop binding 1 cellular amino acid biosynthetic process 5 NLS-bearing protein import into nucleus 3 heterotrimeric G-protein binding 1 cellular response to hydrogen peroxide 5 nuclear envelope organization 3 histidine ammonia-lyase activity 1 cellular response to insulin stimulus 5 nuclear migration 3 histone-arginine N-methyltransferase activity 1 cellular response to oxidative stress 5 nuclear pore complex assembly 3 histone-glutamine methyltransferase activity 1 cellular response to starvation 5 nucleosome disassembly 3 histone acetyltransferase activity (H4-K12 specific) 1 chaperone-mediated protein complex assembly 5 nucleotide-excision repair, DNA damage removal 3 histone acetyltransferase binding 1 cholesterol metabolic process 5 nucleotide-excision repair, DNA gap filling 3 histone deacetylase activity 1 coated pit 5 odontogenesis of dentin-containing tooth 3 histone deacetylase regulator activity 1 Cul4A-RING E3 ubiquitin ligase complex 5 ovarian follicle development 3 histone demethylase activity (H3-R2 specific) 1 cytoskeleton-dependent intracellular transport 5 pentose-phosphate shunt, oxidative branch 3 histone demethylase activity (H4-R3 specific) 1 cytosolic large ribosomal subunit 5 phenylalanyl-tRNA aminoacylation 3 histone kinase activity 1 determination of adult lifespan 5 phototransduction, visible light 3 histone kinase activity (H2A-T120 specific) 1 DNA synthesis involved in DNA repair 5 positive regulation of cell cycle 3 histone methyltransferase binding 1 drug binding 5 positive regulation of cell size 3 HLH domain binding 1 dystrophin-associated glycoprotein complex 5 positive regulation of cellular metabolic process 3 hormone activity 1 ER-associated ubiquitin-dependent protein catabolic process 5 positive regulation of endopeptidase activity 3 hydrolase activity, acting on acid anhydrides 1 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 5 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand 3 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides 1 fatty acid beta-oxidation 5 positive regulation of fat cell differentiation 3 IgG binding 1 Fc-gamma receptor signaling pathway involved in phagocytosis 5 positive regulation of helicase activity 3 IMP dehydrogenase activity 1 G-protein coupled receptor binding 5 positive regulation of macroautophagy 3 importin-alpha export receptor activity 1 G-protein coupled receptor signaling pathway 5 positive regulation of mRNA splicing, via spliceosome 3 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity 1 glycogen biosynthetic process 5 positive regulation of nitric oxide biosynthetic process 3 insulin-like growth factor-activated receptor activity 1 glycogen catabolic process 5 positive regulation of peptidyl-serine phosphorylation 3 insulin-like growth factor binding 1 Golgi organization 5 positive regulation of peptidyl-threonine phosphorylation 3 insulin-like growth factor II binding 1 guanyl-nucleotide exchange factor activity 5 positive regulation of peptidyl-tyrosine phosphorylation 3 insulin receptor binding 1 histone H4 acetylation 5 positive regulation of protein kinase B signaling 3 interferon-gamma binding 1 Ino80 complex 5 positive regulation of proteolysis 3 interleukin-1 binding 1 intermediate filament organization 5 positive regulation of sequence-specific DNA binding transcription factor activity 3 interleukin-2 receptor binding 1 intracellular estrogen receptor signaling pathway 5 positive regulation of smoothened signaling pathway 3 intermediate filament binding 1 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 5 positive regulation of telomere maintenance 3 ion channel activity 1 ligand-dependent nuclear receptor transcription coactivator activity 5 positive regulation of ubiquitin-protein transferase activity 3 ionotropic glutamate receptor binding 1 liver development 5 post-embryonic development 3 iron-responsive element binding 1 locomotory behavior 5 potassium ion import 3 kinase regulator activity 1 MAPK cascade 5 potassium ion transport 3 kinesin binding 1 membrane raft 5 pre-miRNA processing 3 Krueppel-associated box domain binding 1 microfilament motor activity 5 production of siRNA involved in RNA interference 3 L-alanine:2-oxoglutarate aminotransferase activity 1 mitochondrial outer membrane 5 proline biosynthetic process 3 L-allo-threonine aldolase activity 1 mitochondrial ribosome 5 protein import into nucleus, docking 3 L-aminoadipate-semialdehyde dehydrogenase activity 1 mitotic cell cycle checkpoint 5 protein localization to adherens junction 3 L-aspartate transmembrane transporter activity 1 mitotic sister chromatid segregation 5 protein methylation 3 L-glutamine transmembrane transporter activity 1 MLL1 complex 5 protein processing 3 L-serine transmembrane transporter activity 1 mRNA cap binding complex 5 protein targeting to lysosome 3 lactate dehydrogenase activity 1 muscle fiber development 5 purine nucleotide biosynthetic process 3 laminin binding 1 negative regulation of translational initiation 5 regulation of anion transport 3 ligand-dependent nuclear receptor binding 1 negative regulation of type I interferon production 5 regulation of axonogenesis 3 lipase binding 1 negative regulation of viral genome replication 5 regulation of cell adhesion 3 lipase inhibitor activity 1 neurological system process 5 regulation of cell morphogenesis 3 lipid transporter activity 1 neuron projection development 5 regulation of cyclin-dependent protein serine/threonine kinase activity 3 lipoprotein particle receptor binding 1 nuclear chromosome, telomeric region 5 regulation of DNA replication 3 lipoprotein transporter activity 1 nuclear inner membrane 5 regulation of G-protein coupled receptor protein signaling pathway 3 lithium ion binding 1 nuclear periphery 5 regulation of gluconeogenesis involved in cellular glucose homeostasis 3 long-chain-alcohol oxidase activity 1 nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway 5 regulation of heart rate 3 long-chain-aldehyde dehydrogenase activity 1 PcG protein complex 5 regulation of heart rate by cardiac conduction 3 low-density lipoprotein particle binding 1 peptide cross-linking 5 regulation of inflammatory response 3 manganese ion binding 1 peptidyl-serine phosphorylation 5 regulation of insulin secretion 3 mannose-1-phosphate guanylyltransferase activity 1 phosphatase binding 5 regulation of intracellular pH 3 medium-chain-aldehyde dehydrogenase activity 1 platelet aggregation 5 regulation of mRNA splicing, via spliceosome 3 medium-chain acyl-CoA hydrolase activity 1 PML body 5 regulation of multicellular organism growth 3 metalloaminopeptidase activity 1 positive regulation of cell growth 5 regulation of nitric-oxide synthase activity 3 metalloendopeptidase activity 1 positive regulation of G1/S transition of mitotic cell cycle 5 regulation of phosphoprotein phosphatase activity 3 methenyltetrahydrofolate cyclohydrolase activity 1 positive regulation of intrinsic apoptotic signaling pathway 5 regulation of protein phosphorylation 3 methyl-CpG binding 1 positive regulation of mitotic cell cycle 5 regulation of protein transport 3 methylcrotonoyl-CoA carboxylase activity 1 post-Golgi vesicle-mediated transport 5 regulation of proteolysis 3 methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity 1 protein autophosphorylation 5 regulation of Ras GTPase activity 3 MHC class II protein binding 1 protein heterooligomerization 5 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 3 MHC class II receptor activity 1 protein import into nucleus 5 regulation of ryanodine-sensitive calcium-release channel activity 3 misfolded protein binding 1 protein K63-linked ubiquitination 5 regulation of sequence-specific DNA binding transcription factor activity 3 mitochondrial heavy strand promoter anti-sense binding 1 protein localization 5 regulation of smooth muscle cell apoptotic process 3 mitochondrial light strand promoter sense binding 1 protein phosphatase 2A binding 5 regulation of sodium ion transport 3 mitogen-activated protein kinase kinase binding 1 protein refolding 5 regulation of synaptic plasticity 3 mitogen-activated protein kinase kinase kinase binding 1 protein targeting to mitochondrion 5 regulation of synaptic transmission, GABAergic 3 monosaccharide binding 1 protein tyrosine phosphatase activity 5 response to antibiotic 3 monovalent inorganic cation transmembrane transporter activity 1 purine nucleobase metabolic process 5 response to axon injury 3 mRNA 3'-UTR AU-rich region binding 1 pyruvate metabolic process 5 response to cAMP 3 mRNA 5'-UTR binding 1 Rac GTPase binding 5 response to endoplasmic reticulum stress 3 mu-type opioid receptor binding 1 Ran GTPase binding 5 response to exogenous dsRNA 3 muscle alpha-actinin binding 1 regulation of cytoskeleton organization 5 response to gamma radiation 3 myosin VI light chain binding 1 regulation of double-strand break repair via homologous recombination 5 response to glycoside 3 myristoyl-[acyl-carrier-protein] hydrolase activity 1 regulation of RNA biosynthetic process 5 response to hydrogen peroxide 3 N-acylglucosamine-6-phosphate 2-epimerase activity 1 replication fork 5 response to interleukin-1 3 N-terminal myristoylation domain binding 1 response to heat 5 response to light stimulus 3 NAD+ binding 1 response to organic cyclic compound 5 response to peptide hormone 3 NADPH binding 1 response to toxic substance 5 response to reactive oxygen species 3 neurotrophin TRKA receptor binding 1 retina development in camera-type eye 5 response to retinoic acid 3 NF-kappaB-inducing kinase activity 1 retrograde transport, endosome to Golgi 5 response to steroid hormone 3 nitronate monooxygenase activity 1 RISC complex 5 ribosome assembly 3 Notch binding 1 RNA phosphodiester bond hydrolysis, exonucleolytic 5 RNA methylation 3 nuclear localization sequence binding 1 RNA polymerase I activity 5 rRNA transcription 3 nucleoside-triphosphatase activity 1 rRNA binding 5 sister chromatid cohesion 3 nucleoside binding 1 ruffle 5 skeletal system development 3 nucleosomal DNA binding 1 sarcomere organization 5 sodium ion transport 3 nucleosome binding 1 scaffold protein binding 5 somitogenesis 3 nucleotide phosphatase activity, acting on free nucleotides 1 SH3 domain binding 5 spermatid development 3 oleoyl-[acyl-carrier-protein] hydrolase activity 1 skin development 5 spindle assembly 3 ornithine-oxo-acid transaminase activity 1 small ribosomal subunit 5 stress granule assembly 3 oxidative RNA demethylase activity 1 spindle microtubule 5 stress granule disassembly 3 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor 1 spliceosomal complex assembly 5 succinyl-CoA metabolic process 3 oxoglutarate dehydrogenase (NAD+) activity 1 STAGA complex 5 synaptic vesicle endocytosis 3 oxygen binding 1 translation initiation factor binding 5 T cell activation 3 oxygen sensor activity 1 tricarboxylic acid cycle 5 T cell differentiation in thymus 3 palmitoyl-[acyl-carrier-protein] hydrolase activity 1 tRNA binding 5 telomere maintenance via recombination 3 palmitoyl-CoA hydrolase activity 1 vacuolar transport 5 telomere maintenance via semi-conservative replication 3 patched binding 1 viral transcription 5 tetrahydrofolate interconversion 3 peptide alpha-N-acetyltransferase activity 1 vitamin metabolic process 5 tight junction assembly 3 peptide antigen binding 1 water-soluble vitamin metabolic process 5 toll-like receptor 4 signaling pathway 3 peptidyl-asparagine 3-dioxygenase activity 1 3'-5' exonuclease activity 4 transcription initiation from mitochondrial promoter 3 peptidyl-histidine dioxygenase activity 1 actin cytoskeleton reorganization 4 UV-damage excision repair 3 peptidyl-lysine 5-dioxygenase activity 1 actin filament bundle assembly 4 ventricular cardiac muscle cell development 3 peroxisome targeting sequence binding 1 activation of MAPK activity 4 'de novo' CTP biosynthetic process 2 phenylalanine 4-monooxygenase activity 1 activation of MAPKK activity 4 'de novo' IMP biosynthetic process 2 phosphate ion carrier activity 1 acyl-CoA dehydrogenase activity 4 'de novo' pyrimidine nucleobase biosynthetic process 2 phosphatidic acid binding 1 adenosylhomocysteinase activity 4 2-oxoglutarate metabolic process 2 phosphatidylinositol-3-phosphate binding 1 adherens junction organization 4 3'-UTR-mediated mRNA stabilization 2 phosphatidylinositol-4-phosphate binding 1 aggresome 4 activation of Rac GTPase activity 2 phosphatidylinositol-4,5-bisphosphate 3-kinase activity 1 aminopeptidase activity 4 acyl-CoA metabolic process 2 phosphatidylinositol-5-phosphate binding 1 angiogenesis 4 adenosine receptor signaling pathway 2 phosphatidylinositol 3-kinase activity 1 antioxidant activity 4 adenosine to inosine editing 2 phosphatidylinositol phosphate binding 1 apical junction assembly 4 alpha-beta T cell differentiation 2 phosphatidylserine binding 1 ATP-dependent peptidase activity 4 alpha-linolenic acid metabolic process 2 phospholipase inhibitor activity 1 auditory receptor cell stereocilium organization 4 alternative mRNA splicing, via spliceosome 2 phospholipid-hydroperoxide glutathione peroxidase activity 1 axoneme 4 amino acid transport 2 phosphopantetheine binding 1 B cell differentiation 4 anterior/posterior pattern specification 2 phosphoribosylaminoimidazole carboxylase activity 1 branched-chain amino acid catabolic process 4 anterograde axon cargo transport 2 phosphorylase activity 1 calcium-dependent phospholipid binding 4 apoptotic mitochondrial changes 2 poly-pyrimidine tract binding 1 cardiac muscle contraction 4 apoptotic signaling pathway 2 poly(A) binding 1 cell aging 4 aspartate transport 2 polynucleotide adenylyltransferase activity 1 cell growth 4 asymmetric protein localization 2 polysaccharide binding 1 cellular protein complex assembly 4 ATP-dependent chromatin remodeling 2 porin activity 1 cellular response to epidermal growth factor stimulus 4 attachment of spindle microtubules to kinetochore 2 potassium channel regulator activity 1 cellular response to heat 4 auditory receptor cell morphogenesis 2 POZ domain binding 1 cellular response to organic substance 4 axon extension 2 pre-mRNA binding 1 cellular response to UV 4 B-1 B cell homeostasis 2 pre-mRNA intronic binding 1 centriole 4 B cell activation 2 pre-mRNA intronic pyrimidine-rich binding 1 centrosome localization 4 B cell lineage commitment 2 procollagen-proline 3-dioxygenase activity 1 ciliary basal body 4 B cell mediated immunity 2 procollagen-proline 4-dioxygenase activity 1 circadian regulation of gene expression 4 B cell proliferation 2 procollagen galactosyltransferase activity 1 cis-Golgi network 4 barbed-end actin filament capping 2 proline-rich region binding 1 core promoter binding 4 base-excision repair, gap-filling 2 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity 1 CTP synthase activity 4 beta-amyloid clearance 2 protein kinase A catalytic subunit binding 1 Cul4-RING E3 ubiquitin ligase complex 4 bile acid biosynthetic process 2 protein kinase A regulatory subunit binding 1 Cul4B-RING E3 ubiquitin ligase complex 4 biotin metabolic process 2 protein kinase activator activity 1 cyclin binding 4 blastocyst development 2 protein kinase C activity 1 cytokinesis 4 blood vessel endothelial cell migration 2 protein kinase inhibitor activity 1 cytoplasmic microtubule 4 BMP signaling pathway 2 protein N-acetylglucosaminyltransferase activity 1 cytoplasmic mRNA processing body assembly 4 bundle of His cell to Purkinje myocyte communication 2 protein phosphatase 1 binding 1 cytoplasmic side of plasma membrane 4 calcium-mediated signaling 2 protein phosphatase 2B binding 1 DNA-directed DNA polymerase activity 4 calcium ion transmembrane transport 2 protein phosphatase activator activity 1 DNA-directed RNA polymerase II, core complex 4 calcium ion transport 2 protein serine/threonine/tyrosine kinase activity 1 DNA damage checkpoint 4 carbohydrate phosphorylation 2 protein transmembrane transporter activity 1 DNA unwinding involved in DNA replication 4 carboxylic acid metabolic process 2 protein tyrosine kinase inhibitor activity 1 Elongator holoenzyme complex 4 cardiac muscle cell action potential 2 purine nucleobase binding 1 endopeptidase activity 4 cardiac muscle cell differentiation 2 purine nucleotide binding 1 endoplasmic reticulum-Golgi intermediate compartment 4 cardiac muscle fiber development 2 purine ribonucleoside triphosphate binding 1 endosome membrane 4 cardiac muscle tissue morphogenesis 2 pyrophosphatase activity 1 ephrin receptor binding 4 cardiolipin acyl-chain remodeling 2 pyrroline-5-carboxylate reductase activity 1 epithelial cell differentiation 4 carnitine metabolic process, CoA-linked 2 Rab GTPase activator activity 1 ER to Golgi transport vesicle membrane 4 cell communication by electrical coupling involved in cardiac conduction 2 raffinose alpha-galactosidase activity 1 establishment or maintenance of cell polarity 4 cell differentiation involved in embryonic placenta development 2 RAGE receptor binding 1 exon-exon junction complex 4 cellular glucose homeostasis 2 Ral GTPase binding 1 exosome (RNase complex) 4 cellular hyperosmotic salinity response 2 Ras GTPase binding 1 extrinsic component of cytoplasmic side of plasma membrane 4 cellular hypotonic response 2 receptor signaling complex scaffold activity 1 fascia adherens 4 cellular iron ion homeostasis 2 receptor signaling protein activity 1 flavin adenine dinucleotide binding 4 cellular potassium ion homeostasis 2 receptor signaling protein serine/threonine kinase activity 1 forebrain development 4 cellular respiration 2 repressing transcription factor binding 1 formate-tetrahydrofolate ligase activity 4 cellular response to ATP 2 retinoic acid binding 1 G-protein beta/gamma-subunit complex binding 4 cellular response to cadmium ion 2 retinoid X receptor binding 1 gastrulation 4 cellular response to dexamethasone stimulus 2 ribonuclease inhibitor activity 1 gluconeogenesis 4 cellular response to drug 2 ribonuclease MRP activity 1 glucose binding 4 cellular response to fatty acid 2 ribosomal large subunit binding 1 glycogen (starch) synthase activity 4 cellular response to glucagon stimulus 2 RNA-3'-phosphate cyclase activity 1 glycogen metabolic process 4 cellular response to glucocorticoid stimulus 2 RNA-dependent ATPase activity 1 growth 4 cellular response to glucose starvation 2 RNA-directed RNA polymerase activity 1 GTPase activator activity 4 cellular response to hydroxyurea 2 RNA polymerase I CORE element sequence-specific DNA binding 1 heterochromatin 4 cellular response to indole-3-methanol 2 RNA polymerase I CORE element sequence-specific DNA binding transcription factor recruiting transcription factor activity 1 histone acetylation 4 cellular response to interferon-alpha 2 RNA polymerase I transcription factor binding 1 histone H2A monoubiquitination 4 cellular response to lipopolysaccharide 2 RNA polymerase II activating transcription factor binding 1 histone H3-K4 demethylation 4 cellular response to morphine 2 RNA polymerase II core binding 1 histone H3 deacetylation 4 cellular response to retinoic acid 2 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription 1 homeostasis of number of cells 4 cellular response to transforming growth factor beta stimulus 2 RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription 1 Hsp90 protein binding 4 cellular response to X-ray 2 RNA stem-loop binding 1 immune response 4 cellular sodium ion homeostasis 2 RNA uridylyltransferase activity 1 integrin-mediated signaling pathway 4 cellular triglyceride homeostasis 2 RS domain binding 1 intermediate filament cytoskeleton organization 4 centrosome cycle 2 satellite DNA binding 1 intracellular transport 4 ceramide metabolic process 2 scavenger receptor activity 1 isotype switching 4 cerebellum development 2 selenium binding 1 K63-linked polyubiquitin binding 4 chemotaxis 2 sequence-specific DNA binding RNA polymerase II transcription factor activity 1 keratinization 4 cholesterol homeostasis 2 serine-type carboxypeptidase activity 1 kidney development 4 circulatory system process 2 SH2 domain binding 1 kinase binding 4 cis assembly of pre-catalytic spliceosome 2 signal recognition particle binding 1 Ku70:Ku80 complex 4 clathrin-mediated endocytosis 2 single-stranded DNA endodeoxyribonuclease activity 1 membrane coat 4 cochlear nucleus development 2 small GTPase binding 1 MHC class II protein complex binding 4 collagen fibril organization 2 small GTPase regulator activity 1 miRNA binding 4 COPI coating of Golgi vesicle 2 snRNP binding 1 misfolded or incompletely synthesized protein catabolic process 4 CRD-mediated mRNA stabilization 2 sodium channel regulator activity 1 mismatch repair 4 CTP biosynthetic process 2 sodium:dicarboxylate symporter activity 1 mismatched DNA binding 4 CUT catabolic process 2 spectrin binding 1 mitochondrial membrane 4 cytoplasm organization 2 steroid binding 1 mitotic metaphase plate congression 4 cytoplasmic sequestering of NF-kappaB 2 structural constituent of cell wall 1 mitotic nuclear envelope reassembly 4 cytoplasmic sequestering of protein 2 structural constituent of eye lens 1 mitotic spindle 4 cytoskeletal anchoring at plasma membrane 2 structural molecule activity conferring elasticity 1 monoubiquitinated histone H2A deubiquitination 4 defense response to Gram-positive bacterium 2 sulfonylurea receptor binding 1 monoubiquitinated protein deubiquitination 4 dendrite development 2 SUMO-specific isopeptidase activity 1 mRNA polyadenylation 4 deoxyribonucleotide biosynthetic process 2 symporter activity 1 muscle cell cellular homeostasis 4 desmosome assembly 2 Tat protein binding 1 MutSalpha complex 4 desmosome organization 2 telethonin binding 1 N-acetyltransferase activity 4 detection of chemical stimulus involved in sensory perception of bitter taste 2 testosterone dehydrogenase [NAD(P)] activity 1 NAD+ ADP-ribosyltransferase activity 4 determination of left/right symmetry 2 tetrapyrrole binding 1 NADP binding 4 DNA-dependent DNA replication 2 thiamine pyrophosphate binding 1 negative regulation of canonical Wnt signaling pathway 4 DNA biosynthetic process 2 thioesterase binding 1 negative regulation of DNA recombination 4 DNA catabolic process 2 thromboxane A2 receptor binding 1 negative regulation of epidermal growth factor receptor signaling pathway 4 DNA damage induced protein phosphorylation 2 thyrotropin-releasing hormone receptor binding 1 negative regulation of fat cell differentiation 4 DNA dealkylation involved in DNA repair 2 titin binding 1 negative regulation of gene expression 4 DNA packaging 2 Toll-like receptor 4 binding 1 negative regulation of I-kappaB kinase/NF-kappaB signaling 4 DNA replication-dependent nucleosome assembly 2 transaminase activity 1 negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway 4 DNA replication proofreading 2 transferase activity 1 negative regulation of phosphatase activity 4 DNA strand renaturation 2 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer 1 negative regulation of protein kinase activity 4 dorsal/ventral pattern formation 2 transforming growth factor beta receptor binding 1 negative regulation of skeletal muscle tissue development 4 dosage compensation by inactivation of X chromosome 2 translation regulator activity 1 negative regulation of translation involved in gene silencing by miRNA 4 drug metabolic process 2 translation release factor activity, codon specific 1 neuromuscular junction 4 ectoderm development 2 translation repressor activity 1 neutral amino acid transmembrane transporter activity 4 embryonic cleavage 2 translation termination factor activity 1 NF-kappaB binding 4 embryonic limb morphogenesis 2 transmembrane signaling receptor activity 1 nitric-oxide synthase regulator activity 4 embryonic skeletal system development 2 tRNA (adenine-N1-)-methyltransferase activity 1 nuclear-transcribed mRNA catabolic process 4 endocrine pancreas development 2 tRNA (guanine-N7-)-methyltransferase activity 1 nuclear envelope lumen 4 endoplasmic reticulum organization 2 tRNA guanylyltransferase activity 1 nuclear migration along microfilament 4 endosome organization 2 tropomyosin binding 1 nuclear pore organization 4 ephrin receptor signaling pathway 2 type 3 metabotropic glutamate receptor binding 1 nuclear pore outer ring 4 epithelial cell-cell adhesion 2 U5 snRNA binding 1 nucleic acid phosphodiester bond hydrolysis 4 epithelial tube branching involved in lung morphogenesis 2 U6 snRNA binding 1 nucleobase-containing compound metabolic process 4 ERK1 and ERK2 cascade 2 ubiquitin protein ligase activity 1 nucleobase-containing small molecule interconversion 4 erythrocyte development 2 UTP binding 1 nucleotide-binding oligomerization domain containing signaling pathway 4 establishment of integrated proviral latency 2 virion binding 1 NuRD complex 4 establishment of skin barrier 2 virus receptor activity 1 organ regeneration 4 establishment or maintenance of microtubule cytoskeleton polarity 2 vitamin binding 1 peptidyl-tyrosine dephosphorylation 4 exit from mitosis 2 vitamin D receptor binding 1 peroxisomal matrix 4 extracellular matrix disassembly 2 WD40-repeat domain binding 1 phenylalanine-tRNA ligase activity 4 extrinsic apoptotic signaling pathway 2 Y-form DNA binding 1 phospholipid metabolic process 4 fatty acid beta-oxidation using acyl-CoA dehydrogenase 2 phosphotransferase activity, alcohol group as acceptor 4 fatty acid beta-oxidation using acyl-CoA oxidase 2 positive regulation of catalytic activity 4 fatty acid metabolic process 2 positive regulation of cholesterol efflux 4 female pregnancy 2 positive regulation of interferon-alpha production 4 folic acid-containing compound biosynthetic process 2 positive regulation of protein import into nucleus 4 fructose metabolic process 2 positive regulation of protein serine/threonine kinase activity 4 fucose metabolic process 2 positive regulation of Wnt signaling pathway 4 galactose metabolic process 2 postsynaptic density 4 galactosylceramide catabolic process 2 potassium ion binding 4 gamma-aminobutyric acid signaling pathway 2 proteasome binding 4 glucose 6-phosphate metabolic process 2 proteasome core complex, alpha-subunit complex 4 glutaminyl-tRNA aminoacylation 2 protein autoubiquitination 4 glycerophospholipid biosynthetic process 2 protein export from nucleus 4 glycine metabolic process 2 protein localization to nucleus 4 glycoside catabolic process 2 protein oligomerization 4 glycosphingolipid metabolic process 2 protein targeting to plasma membrane 4 glycosylceramide catabolic process 2 protein tetramerization 4 GMP biosynthetic process 2 proton-transporting ATP synthase activity, rotational mechanism 4 Golgi to plasma membrane protein transport 2 proton transport 4 heart contraction 2 pseudopodium 4 heme biosynthetic process 2 purine ribonucleoside monophosphate biosynthetic process 4 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules 2 pyruvate kinase activity 4 histidine catabolic process 2 Rab GTPase binding 4 histone deacetylation 2 receptor complex 4 histone H3-K36 demethylation 2 reciprocal meiotic recombination 4 histone H3-R17 methylation 2 regulation of blood pressure 4 histone H4-K16 acetylation 2 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion 4 histone H4-K5 acetylation 2 regulation of growth 4 histone H4-K8 acetylation 2 regulation of mitotic cell cycle 4 histone methylation 2 regulation of proteasomal protein catabolic process 4 histone mRNA catabolic process 2 regulation of small GTPase mediated signal transduction 4 hydrogen peroxide biosynthetic process 2 regulation of the force of heart contraction 4 insulin secretion 2 response to calcium ion 4 intermediate filament bundle assembly 2 response to estradiol 4 internal protein amino acid acetylation 2 response to estrogen 4 intra-S DNA damage checkpoint 2 response to hormone 4 intracellular steroid hormone receptor signaling pathway 2 response to insulin 4 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress 2 response to zinc ion 4 leucine import 2 ribosomal small subunit binding 4 lipopolysaccharide-mediated signaling pathway 2 RNA helicase activity 4 long-chain fatty-acyl-CoA biosynthetic process 2 RNA phosphodiester bond hydrolysis 4 lung morphogenesis 2 rRNA methylation 4 lysine catabolic process 2 sarcoplasmic reticulum 4 malate-aspartate shuttle 2 serine-type endopeptidase inhibitor activity 4 male meiosis 2 single-stranded RNA binding 4 male meiosis I 2 skeletal muscle tissue development 4 mammary gland duct morphogenesis 2 sodium:potassium-exchanging ATPase activity 4 MAPK import into nucleus 2 sodium:potassium-exchanging ATPase complex 4 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 2 somatic hypermutation of immunoglobulin genes 4 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 2 somatic recombination of immunoglobulin gene segments 4 medium-chain fatty acid metabolic process 2 spectrin 4 meiotic cell cycle 2 sphingolipid metabolic process 4 meiotic mismatch repair 2 tau-protein kinase activity 4 membrane fusion 2 TBP-class protein binding 4 membrane protein ectodomain proteolysis 2 telomeric DNA binding 4 membrane repolarization during cardiac muscle cell action potential 2 threonine-type endopeptidase activity 4 microtubule anchoring 2 toll-like receptor signaling pathway 4 microtubule anchoring at microtubule organizing center 2 transcription from RNA polymerase III promoter 4 microtubule bundle formation 2 translation elongation factor activity 4 microtubule organizing center organization 2 tRNA aminoacylation 4 midbrain development 2 U4/U6 x U5 tri-snRNP complex 4 minus-end-directed organelle transport along microtubule 2 ubiquitin-ubiquitin ligase activity 4 mitochondrion morphogenesis 2 V(D)J recombination 4 mitotic chromosome condensation 2 viral entry into host cell 4 mitotic G1 DNA damage checkpoint 2 wound healing 4 mRNA 3'-splice site recognition 2 zonula adherens 4 mRNA catabolic process 2 3'-5'-exoribonuclease activity 3 mRNA splice site selection 2 acetyl-CoA metabolic process 3 mRNA stabilization 2 actin crosslink formation 3 mucosal immune response 2 actin filament capping 3 MyD88-independent toll-like receptor signaling pathway 2 actin filament organization 3 myelination 2 activation of phospholipase C activity 3 myeloid cell homeostasis 2 actomyosin 3 negative regulation of actin filament depolymerization 2 actomyosin structure organization 3 negative regulation of angiogenesis 2 Ada2/Gcn5/Ada3 transcription activator complex 3 negative regulation of apoptotic signaling pathway 2 adult heart development 3 negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process 2 adult locomotory behavior 3 negative regulation of B cell activation 2 anaphase-promoting complex 3 negative regulation of beta-amyloid formation 2 androgen receptor signaling pathway 3 negative regulation of cAMP-dependent protein kinase activity 2 angiotensin maturation 3 negative regulation of cardiac muscle hypertrophy 2 aorta morphogenesis 3 negative regulation of cell death 2 apical junction complex 3 negative regulation of cell differentiation 2 apoptotic cell clearance 3 negative regulation of cell migration 2 armadillo repeat domain binding 3 negative regulation of circadian rhythm 2 ATP hydrolysis coupled proton transport 3 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process 2 ATP metabolic process 3 negative regulation of cytosolic calcium ion concentration 2 ATP synthesis coupled proton transport 3 negative regulation of defense response to virus 2 basement membrane 3 negative regulation of dendrite morphogenesis 2 beta-amyloid binding 3 negative regulation of DNA damage response, signal transduction by p53 class mediator 2 beta-catenin binding 3 negative regulation of DNA endoreduplication 2 beta-tubulin binding 3 negative regulation of DNA recombination at telomere 2 bile acid metabolic process 3 negative regulation of epithelial cell proliferation 2 bone development 3 negative regulation of fibroblast proliferation 2 calcium-dependent protein binding 3 negative regulation of focal adhesion assembly 2 camera-type eye development 3 negative regulation of heart contraction 2 cardiac myofibril assembly 3 negative regulation of helicase activity 2 caveola 3 negative regulation of hydrogen peroxide-induced neuron death 2 cell-cell junction assembly 3 negative regulation of inflammatory response 2 cell-cell junction organization 3 negative regulation of innate immune response 2 cell surface receptor signaling pathway 3 negative regulation of interleukin-6 production 2 cellular aldehyde metabolic process 3 negative regulation of intracellular estrogen receptor signaling pathway 2 cellular carbohydrate metabolic process 3 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 2 cellular response to amino acid stimulus 3 negative regulation of JNK cascade 2 cellular response to calcium ion 3 negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process 2 cellular response to interferon-gamma 3 negative regulation of mitotic cell cycle 2 cellular response to mechanical stimulus 3 negative regulation of neuroblast proliferation 2 cellular response to misfolded protein 3 negative regulation of neurofibrillary tangle assembly 2 cellular response to organic cyclic compound 3 negative regulation of neurogenesis 2 cellular response to steroid hormone stimulus 3 negative regulation of neuron projection development 2 CENP-A containing nucleosome assembly 3 negative regulation of NF-kappaB import into nucleus 2 central nervous system development 3 negative regulation of nitric oxide biosynthetic process 2 centrosome duplication 3 negative regulation of osteoblast differentiation 2 chromatin-mediated maintenance of transcription 3 negative regulation of peptidase activity 2 ciliary transition zone 3 negative regulation of peptidyl-cysteine S-nitrosylation 2 cilium assembly 3 negative regulation of peptidyl-serine phosphorylation 2 cilium morphogenesis 3 negative regulation of peroxisome proliferator activated receptor signaling pathway 2 circadian rhythm 3 negative regulation of phosphatidylinositol 3-kinase signaling 2 clathrin-coated endocytic vesicle membrane 3 negative regulation of phosphorylation 2 clathrin binding 3 negative regulation of platelet-derived growth factor receptor-beta signaling pathway 2 cohesin core heterodimer 3 negative regulation of potassium ion transmembrane transport 2 collagen binding 3 negative regulation of potassium ion transmembrane transporter activity 2 condensed chromosome 3 negative regulation of programmed cell death 2 contractile fiber 3 negative regulation of prostaglandin biosynthetic process 2 copper ion binding 3 negative regulation of protein refolding 2 cornified envelope 3 negative regulation of protein serine/threonine kinase activity 2 cortical actin cytoskeleton 3 negative regulation of release of cytochrome c from mitochondria 2 cytokine production 3 negative regulation of retinoic acid receptor signaling pathway 2 cytoskeletal anchoring at nuclear membrane 3 negative regulation of RNA export from nucleus 2 cytosolic proteasome complex 3 negative regulation of rubidium ion transmembrane transporter activity 2 cytosolic small ribosomal subunit 3 negative regulation of rubidium ion transport 2 dendrite cytoplasm 3 negative regulation of smooth muscle cell migration 2 DNA-dependent ATPase activity 3 negative regulation of substrate adhesion-dependent cell spreading 2 DNA-directed RNA polymerase II, holoenzyme 3 negative regulation of tau-protein kinase activity 2 DNA-templated transcription, initiation 3 negative regulation of telomeric RNA transcription from RNA pol II promoter 2 DNA methylation 3 negative regulation of TOR signaling 2 DNA replication-independent nucleosome assembly 3 negative regulation of tumor necrosis factor production 2 DNA replication factor A complex 3 negative regulation of tyrosine phosphorylation of Stat3 protein 2 embryonic organ development 3 negative regulation of ubiquitin-protein transferase activity 2 endocytic vesicle 3 negative regulation of vascular permeability 2 endocytic vesicle lumen 3 negative regulation of viral release from host cell 2 endocytic vesicle membrane 3 neurofilament cytoskeleton organization 2 endomembrane system 3 neuromuscular junction development 2 endopeptidase activator activity 3 neuromuscular process 2 endosomal transport 3 neuron apoptotic process 2 epithelial to mesenchymal transition 3 neuron death 2 ER to Golgi transport vesicle 3 neuron projection extension 2 erythrocyte differentiation 3 neutral amino acid transport 2 establishment of protein localization 3 neutrophil chemotaxis 2 exocytosis 3 neutrophil homeostasis 2 extrinsic component of membrane 3 nuclear matrix anchoring at nuclear membrane 2 fatty-acyl-CoA binding 3 nucleolus organization 2 fatty acid biosynthetic process 3 nucleotide phosphorylation 2 fatty acid homeostasis 3 nucleus organization 2 ferrous iron transmembrane transporter activity 3 oocyte maturation 2 ferrous iron transport 3 oogenesis 2 filopodium membrane 3 organ morphogenesis 2 formation of cytoplasmic translation initiation complex 3 ossification 2 GAIT complex 3 oxidation-dependent protein catabolic process 2 gene silencing by RNA 3 pentose biosynthetic process 2 glucocorticoid receptor signaling pathway 3 peptide biosynthetic process 2 GTPase inhibitor activity 3 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine 2 guanine/thymine mispair binding 3 peptidyl-arginine N-methylation 2 hair cycle 3 peripheral nervous system myelin maintenance 2 hemidesmosome assembly 3 pigmentation 2 heparin binding 3 placenta development 2 hepatocyte apoptotic process 3 pore complex assembly 2 hippocampus development 3 positive chemotaxis 2 histone acetyltransferase complex 3 positive regulation of angiogenesis 2 histone H2A acetylation 3 positive regulation of attachment of spindle microtubules to kinetochore 2 histone H2A K63-linked deubiquitination 3 positive regulation of blood vessel endothelial cell migration 2 histone H3 acetylation 3 positive regulation of BMP signaling pathway 2 histone ubiquitination 3 positive regulation of cAMP-dependent protein kinase activity 2 homophilic cell adhesion via plasma membrane adhesion molecules 3 positive regulation of canonical Wnt signaling pathway 2 hydrogen peroxide catabolic process 3 positive regulation of cell-matrix adhesion 2 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 3 positive regulation of cell aging 2 I band 3 positive regulation of cell cycle arrest 2 inactivation of MAPK activity 3 positive regulation of cellular component movement 2 insulin receptor substrate binding 3 positive regulation of choline O-acetyltransferase activity 2 integral component of endoplasmic reticulum membrane 3 positive regulation of circadian rhythm 2 intercellular canaliculus 3 positive regulation of cyclic-nucleotide phosphodiesterase activity 2 intrinsic apoptotic signaling pathway by p53 class mediator 3 positive regulation of cytokinesis 2 ion transmembrane transport 3 positive regulation of dipeptide transmembrane transport 2 ion transport 3 positive regulation of DNA-templated transcription, elongation 2 iron-sulfur cluster binding 3 positive regulation of epithelial cell proliferation 2 L-ascorbic acid binding 3 positive regulation of fibroblast proliferation 2 L-lactate dehydrogenase activity 3 positive regulation of G2/M transition of mitotic cell cycle 2 L-proline biosynthetic process 3 positive regulation of granulocyte differentiation 2 lamin binding 3 positive regulation of histone deacetylation 2 lamin filament 3 positive regulation of histone H3-K4 methylation 2 late endosome 3 positive regulation of inclusion body assembly 2 lateral ventricle development 3 positive regulation of interferon-beta production 2 lipid transport 3 positive regulation of interferon-gamma production 2 lipoprotein metabolic process 3 positive regulation of interleukin-1 beta production 2 long-chain-enoyl-CoA hydratase activity 3 positive regulation of intracellular protein transport 2 low-density lipoprotein particle receptor binding 3 positive regulation of lipid transport 2 lung development 3 positive regulation of macrophage apoptotic process 2 Lys48-specific deubiquitinase activity 3 positive regulation of mRNA 3'-end processing 2 lysosomal membrane 3 positive regulation of muscle cell differentiation 2 M band 3 positive regulation of neurogenesis 2 maintenance of DNA methylation 3 positive regulation of neuron apoptotic process 2 MAP kinase activity 3 positive regulation of neuron projection development 2 mast cell granule 3 positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 2 maternal process involved in female pregnancy 3 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening 2 mediator complex 3 positive regulation of nuclear cell cycle DNA replication 2 meiotic nuclear division 3 positive regulation of osteoclast differentiation 2 methylated histone binding 3 positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway 2 methylenetetrahydrofolate dehydrogenase (NADP+) activity 3 positive regulation of pathway-restricted SMAD protein phosphorylation 2 micro-ribonucleoprotein complex 3 positive regulation of phosphatidylinositol 3-kinase signaling 2 miRNA loading onto RISC involved in gene silencing by miRNA 3 positive regulation of pinocytosis 2 mitochondrial ATP synthesis coupled proton transport 3 positive regulation of potassium ion transport 2 mitochondrial envelope 3 positive regulation of protein autophosphorylation 2 mitochondrial fusion 3 positive regulation of protein complex assembly 2 mitochondrial proton-transporting ATP synthase complex 3 positive regulation of protein export from nucleus 2 mitochondrion degradation 3 positive regulation of protein import into nucleus, translocation 2 mitogen-activated protein kinase binding 3 positive regulation of protein kinase activity 2 mitotic sister chromatid cohesion 3 positive regulation of protein oligomerization 2 mitotic spindle checkpoint 3 positive regulation of protein secretion 2 morphogenesis of an epithelium 3 positive regulation of protein ubiquitination 2 morphogenesis of embryonic epithelium 3 positive regulation of Ras GTPase activity 2 Mre11 complex 3 positive regulation of reactive oxygen species metabolic process 2 mRNA cleavage 3 positive regulation of response to DNA damage stimulus 2 muscle cell differentiation 3 positive regulation of retinoic acid receptor signaling pathway 2 muscle myosin complex 3 positive regulation of RIG-I signaling pathway 2 MyD88-dependent toll-like receptor signaling pathway 3 positive regulation of signal transduction 2 myofibril 3 positive regulation of sodium ion transmembrane transporter activity 2 myosin II filament 3 positive regulation of synaptic transmission, GABAergic 2 negative regulation of cyclin-dependent protein serine/threonine kinase activity 3 positive regulation of T cell activation 2 negative regulation of DNA replication 3 positive regulation of thymocyte apoptotic process 2 negative regulation of double-strand break repair 3 positive regulation of transcription factor import into nucleus 2 negative regulation of extrinsic apoptotic signaling pathway 3 positive regulation of transcription from RNA polymerase I promoter 2 negative regulation of GTPase activity 3 positive regulation of transcription from RNA polymerase III promoter 2 negative regulation of histone H2A K63-linked ubiquitination 3 positive regulation of tumor necrosis factor biosynthetic process 2 negative regulation of MAP kinase activity 3 postreplication repair 2 negative regulation of neuron death 3 programmed cell death 2 negative regulation of nitric-oxide synthase activity 3 proteasomal protein catabolic process 2 negative regulation of proteasomal ubiquitin-dependent protein catabolic process 3 proteasome assembly 2 negative regulation of protein binding 3 protein ADP-ribosylation 2 negative regulation of protein catabolic process 3 protein deacetylation 2 negative regulation of protein dephosphorylation 3 protein deneddylation 2 negative regulation of protein kinase activity by regulation of protein phosphorylation 3 protein glycosylation 2 negative regulation of protein kinase B signaling 3 protein hexamerization 2 negative regulation of protein phosphorylation 3 protein import into mitochondrial outer membrane 2 negative regulation of sequence-specific DNA binding transcription factor activity 3 protein K11-linked ubiquitination 2 negative regulation of Wnt signaling pathway 3 protein K29-linked deubiquitination 2 neural tube development 3 protein K33-linked deubiquitination 2 neuromuscular process controlling balance 3 protein K48-linked ubiquitination 2 neuron differentiation 3 protein localization to cell surface 2 nitric-oxide synthase binding 3 protein neddylation 2 nitric oxide metabolic process 3 protein poly-ADP-ribosylation 2 NLS-bearing protein import into nucleus 3 protein retention in Golgi apparatus 2 nonhomologous end joining complex 3 protein sumoylation 2 NuA4 histone acetyltransferase complex 3 protoporphyrinogen IX metabolic process 2 nuclear envelope organization 3 purine nucleobase biosynthetic process 2 nuclear migration 3 pyrimidine dimer repair by nucleotide-excision repair 2 nuclear pore complex assembly 3 pyrimidine nucleobase metabolic process 2 nuclear telomere cap complex 3 pyrimidine nucleotide biosynthetic process 2 nucleosome disassembly 3 reactive oxygen species metabolic process 2 nucleotide-excision repair, DNA damage removal 3 receptor internalization 2 nucleotide-excision repair, DNA gap filling 3 regulation of actin cytoskeleton organization 2 odontogenesis of dentin-containing tooth 3 regulation of autophagy 2 ovarian follicle development 3 regulation of bile acid biosynthetic process 2 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 3 regulation of cardiac muscle cell contraction 2 paraspeckles 3 regulation of cell differentiation 2 pentose-phosphate shunt, oxidative branch 3 regulation of cell growth 2 peroxisome proliferator activated receptor binding 3 regulation of cell size 2 phenylalanyl-tRNA aminoacylation 3 regulation of cellular response to heat 2 phosphatidylinositol-3,4,5-trisphosphate binding 3 regulation of cholesterol transport 2 phosphogluconate dehydrogenase (decarboxylating) activity 3 regulation of chromosome segregation 2 photoreceptor connecting cilium 3 regulation of cytokinesis 2 phototransduction, visible light 3 regulation of defense response to virus by host 2 platelet alpha granule lumen 3 regulation of defense response to virus by virus 2 positive regulation of cell cycle 3 regulation of DNA-templated transcription, elongation 2 positive regulation of cell size 3 regulation of DNA damage checkpoint 2 positive regulation of cellular metabolic process 3 regulation of DNA methylation 2 positive regulation of endopeptidase activity 3 regulation of DNA repair 2 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand 3 regulation of endodeoxyribonuclease activity 2 positive regulation of fat cell differentiation 3 regulation of gene expression by genetic imprinting 2 positive regulation of helicase activity 3 regulation of germinal center formation 2 positive regulation of macroautophagy 3 regulation of glucose metabolic process 2 positive regulation of mRNA splicing, via spliceosome 3 regulation of histone H3-K9 acetylation 2 positive regulation of nitric oxide biosynthetic process 3 regulation of I-kappaB kinase/NF-kappaB signaling 2 positive regulation of peptidyl-serine phosphorylation 3 regulation of inclusion body assembly 2 positive regulation of peptidyl-threonine phosphorylation 3 regulation of intracellular estrogen receptor signaling pathway 2 positive regulation of peptidyl-tyrosine phosphorylation 3 regulation of JNK cascade 2 positive regulation of protein kinase B signaling 3 regulation of keratinocyte differentiation 2 positive regulation of proteolysis 3 regulation of MAPK cascade 2 positive regulation of sequence-specific DNA binding transcription factor activity 3 regulation of mitochondrial membrane permeability 2 positive regulation of smoothened signaling pathway 3 regulation of mitochondrial membrane potential 2 positive regulation of telomere maintenance 3 regulation of mRNA processing 2 positive regulation of ubiquitin-protein transferase activity 3 regulation of muscle contraction 2 post-embryonic development 3 regulation of neuron apoptotic process 2 potassium ion import 3 regulation of neuron differentiation 2 potassium ion transport 3 regulation of opioid receptor signaling pathway 2 pre-miRNA processing 3 regulation of peroxisome proliferator activated receptor signaling pathway 2 preribosome, small subunit precursor 3 regulation of phospholipase A2 activity 2 production of siRNA involved in RNA interference 3 regulation of phosphorylation 2 proline biosynthetic process 3 regulation of proteasomal ubiquitin-dependent protein catabolic process 2 protein-arginine N-methyltransferase activity 3 regulation of protein binding 2 protein import into nucleus, docking 3 regulation of protein deubiquitination 2 protein kinase C inhibitor activity 3 regulation of protein localization 2 protein localization to adherens junction 3 regulation of Rap GTPase activity 2 protein methylation 3 regulation of rhodopsin mediated signaling pathway 2 protein processing 3 regulation of RNA splicing 2 protein targeting to lysosome 3 regulation of signal transduction 2 Prp19 complex 3 regulation of skeletal muscle contraction 2 purine nucleotide biosynthetic process 3 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion 2 receptor tyrosine kinase binding 3 regulation of sodium ion transmembrane transporter activity 2 regulation of anion transport 3 regulation of stem cell maintenance 2 regulation of axonogenesis 3 regulation of striated muscle contraction 2 regulation of cell adhesion 3 regulation of transcription from RNA polymerase II promoter in response to hypoxia 2 regulation of cell morphogenesis 3 regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage 2 regulation of cyclin-dependent protein serine/threonine kinase activity 3 regulation of translational fidelity 2 regulation of DNA replication 3 regulation of translational initiation in response to stress 2 regulation of G-protein coupled receptor protein signaling pathway 3 regulation of translational termination 2 regulation of gluconeogenesis involved in cellular glucose homeostasis 3 regulation of type I interferon-mediated signaling pathway 2 regulation of heart rate 3 regulation of type I interferon production 2 regulation of heart rate by cardiac conduction 3 regulation of viral transcription 2 regulation of inflammatory response 3 regulation of voltage-gated calcium channel activity 2 regulation of insulin secretion 3 regulation of Wnt signaling pathway 2 regulation of intracellular pH 3 relaxation of cardiac muscle 2 regulation of mRNA splicing, via spliceosome 3 relaxation of vascular smooth muscle 2 regulation of multicellular organism growth 3 release from viral latency 2 regulation of nitric-oxide synthase activity 3 release of cytochrome c from mitochondria 2 regulation of phosphoprotein phosphatase activity 3 removal of superoxide radicals 2 regulation of protein phosphorylation 3 replication fork processing 2 regulation of protein transport 3 replicative senescence 2 regulation of proteolysis 3 response to amine 2 regulation of Ras GTPase activity 3 response to amphetamine 2 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 3 response to arsenic-containing substance 2 regulation of ryanodine-sensitive calcium-release channel activity 3 response to cold 2 regulation of sequence-specific DNA binding transcription factor activity 3 response to epidermal growth factor 2 regulation of smooth muscle cell apoptotic process 3 response to glucocorticoid 2 regulation of sodium ion transport 3 response to glucose 2 regulation of synaptic plasticity 3 response to hyperoxia 2 regulation of synaptic transmission, GABAergic 3 response to interferon-alpha 2 response to antibiotic 3 response to ischemia 2 response to axon injury 3 response to lead ion 2 response to cAMP 3 response to lithium ion 2 response to endoplasmic reticulum stress 3 response to mechanical stimulus 2 response to exogenous dsRNA 3 response to mercury ion 2 response to gamma radiation 3 response to metal ion 2 response to glycoside 3 response to methylmercury 2 response to hydrogen peroxide 3 response to molecule of bacterial origin 2 response to interleukin-1 3 response to nutrient levels 2 response to light stimulus 3 response to other organism 2 response to peptide hormone 3 response to platinum ion 2 response to reactive oxygen species 3 response to radiation 2 response to retinoic acid 3 response to salt stress 2 response to steroid hormone 3 response to superoxide 2 Rho GTPase binding 3 response to testosterone 2 ribonuclease P activity 3 response to tumor necrosis factor 2 ribosome assembly 3 response to UV-B 2 RNA methylation 3 response to vitamin E 2 RNA methyltransferase activity 3 response to wounding 2 RNA polymerase II core promoter proximal region sequence-specific DNA binding 3 retrograde axon cargo transport 2 RNA polymerase II transcription cofactor activity 3 retrograde vesicle-mediated transport, Golgi to ER 2 RNA polymerase II transcription factor binding 3 rhodopsin mediated signaling pathway 2 rough endoplasmic reticulum 3 ribosomal large subunit biogenesis 2 rRNA methyltransferase activity 3 righting reflex 2 rRNA transcription 3 RNA phosphodiester bond hydrolysis, endonucleolytic 2 ruffle membrane 3 RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript 2 serine-type endopeptidase activity 3 rRNA modification 2 SH3/SH2 adaptor activity 3 second-messenger-mediated signaling 2 sister chromatid cohesion 3 seminiferous tubule development 2 site of double-strand break 3 sensory perception of pain 2 skeletal system development 3 Sertoli cell development 2 SMAD binding 3 seryl-tRNA aminoacylation 2 small-subunit processome 3 signal transduction in response to DNA damage 2 small nuclear ribonucleoprotein complex 3 signal transduction involved in DNA damage checkpoint 2 smooth endoplasmic reticulum 3 skeletal muscle atrophy 2 sodium ion transport 3 skeletal muscle contraction 2 somitogenesis 3 skeletal muscle fiber development 2 spermatid development 3 skeletal muscle myosin thick filament assembly 2 spindle assembly 3 skeletal muscle thin filament assembly 2 stress granule assembly 3 skeletal system morphogenesis 2 stress granule disassembly 3 smooth muscle contraction 2 striated muscle thin filament 3 smoothened signaling pathway 2 structural constituent of nuclear pore 3 snRNA transcription from RNA polymerase II promoter 2 succinyl-CoA metabolic process 3 snRNA transcription from RNA polymerase III promoter 2 SUMO binding 3 sodium ion export from cell 2 SUN-KASH complex 3 sperm motility 2 supraspliceosomal complex 3 sphingolipid biosynthetic process 2 Swr1 complex 3 spindle assembly checkpoint 2 synaptic vesicle endocytosis 3 spindle assembly involved in mitosis 2 T cell activation 3 spindle organization 2 T cell differentiation in thymus 3 spliceosomal snRNP assembly 2 telomere maintenance via recombination 3 sprouting angiogenesis 2 telomere maintenance via semi-conservative replication 3 stem cell division 2 tetrahydrofolate interconversion 3 stem cell maintenance 2 tight junction assembly 3 stress-activated MAPK cascade 2 toll-like receptor 4 signaling pathway 3 striated muscle contraction 2 TPR domain binding 3 substrate-dependent cell migration, cell extension 2 transcription factor TFIID complex 3 superoxide metabolic process 2 transcription initiation from mitochondrial promoter 3 synaptonemal complex assembly 2 transcriptionally active chromatin 3 T cell lineage commitment 2 transferase activity, transferring acyl groups other than amino-acyl groups 3 T cell proliferation 2 translation activator activity 3 T cell receptor signaling pathway 2 tubulin binding 3 telencephalon development 2 ubiquitin-specific protease binding 3 telomere maintenance via telomerase 2 UV-damage excision repair 3 telomere maintenance via telomere lengthening 2 ventricular cardiac muscle cell development 3 termination of RNA polymerase III transcription 2 vinculin binding 3 tissue regeneration 2 viral nucleocapsid 3 toll-like receptor 10 signaling pathway 2 'de novo' CTP biosynthetic process 2 toll-like receptor 2 signaling pathway 2 'de novo' IMP biosynthetic process 2 toll-like receptor 3 signaling pathway 2 'de novo' pyrimidine nucleobase biosynthetic process 2 toll-like receptor 5 signaling pathway 2 1-phosphatidylinositol-3-kinase activity 2 toll-like receptor 9 signaling pathway 2 2-oxoglutarate metabolic process 2 toll-like receptor TLR1:TLR2 signaling pathway 2 2 iron, 2 sulfur cluster binding 2 toll-like receptor TLR6:TLR2 signaling pathway 2 3'-UTR-mediated mRNA stabilization 2 transcription elongation from RNA polymerase III promoter 2 3-hydroxyisobutyrate dehydrogenase activity 2 transcription from mitochondrial promoter 2 4-alpha-glucanotransferase activity 2 translesion synthesis 2 4-alpha-hydroxytetrahydrobiopterin dehydratase activity 2 transmission of nerve impulse 2 4 iron, 4 sulfur cluster binding 2 TRIF-dependent toll-like receptor signaling pathway 2 5'-deoxyribose-5-phosphate lyase activity 2 triglyceride biosynthetic process 2 6-phosphofructokinase activity 2 triglyceride mobilization 2 7S RNA binding 2 tumor necrosis factor-mediated signaling pathway 2 A band 2 type I interferon signaling pathway 2 acetyl-CoA C-acyltransferase activity 2 unsaturated fatty acid metabolic process 2 acetyl-CoA carboxylase activity 2 UTP biosynthetic process 2 acid-amino acid ligase activity 2 vasculogenesis 2 activation of Rac GTPase activity 2 ventricular cardiac muscle cell action potential 2 acyl-CoA hydrolase activity 2 ventricular compact myocardium morphogenesis 2 acyl-CoA metabolic process 2 ventricular system development 2 adenosine receptor signaling pathway 2 vesicle transport along microtubule 2 adenosine to inosine editing 2 viral penetration into host nucleus 2 adenyl nucleotide binding 2 visual learning 2 adherens junction 2 visual perception 2 aldehyde dehydrogenase (NAD) activity 2 white fat cell differentiation 2 alkylbase DNA N-glycosylase activity 2 xenobiotic metabolic process 2 alpha-beta T cell differentiation 2 'de novo' protein folding 1 alpha-catenin binding 2 'de novo' UMP biosynthetic process 1 alpha-galactosidase activity 2 3'-UTR-mediated mRNA destabilization 1 alpha-L-fucosidase activity 2 5-phosphoribose 1-diphosphate biosynthetic process 1 alpha-linolenic acid metabolic process 2 actin filament polymerization 1 alternative mRNA splicing, via spliceosome 2 actin filament severing 1 amino acid binding 2 actin polymerization or depolymerization 1 amino acid transport 2 actin rod assembly 1 aminoacyl-tRNA editing activity 2 activation of adenylate cyclase activity 1 aminoacylase activity 2 activation of innate immune response 1 amylo-alpha-1,6-glucosidase activity 2 activation of mitotic anaphase-promoting complex activity 1 anterior/posterior pattern specification 2 activation of NF-kappaB-inducing kinase activity 1 anterograde axon cargo transport 2 activation of protein kinase A activity 1 apicolateral plasma membrane 2 activation of protein kinase activity 1 apolipoprotein binding 2 activation of Rap GTPase activity 1 apoptotic mitochondrial changes 2 adaptive immune response 1 apoptotic signaling pathway 2 adenylate cyclase-inhibiting dopamine receptor signaling pathway 1 ARF guanyl-nucleotide exchange factor activity 2 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway 1 arginase activity 2 adiponectin-activated signaling pathway 1 aspartate carbamoyltransferase activity 2 adult behavior 1 aspartate transport 2 adult feeding behavior 1 aspartic-type endopeptidase activity 2 adult walking behavior 1 asymmetric protein localization 2 aerobic respiration 1 ATP-dependent 5'-3' DNA helicase activity 2 aggresome assembly 1 ATP-dependent chromatin remodeling 2 amino acid transmembrane transport 1 ATPase activity, coupled 2 androgen metabolic process 1 ATPase activity, coupled to transmembrane movement of substances 2 angiotensin-activated signaling pathway 1 attachment of spindle microtubules to kinetochore 2 anion transport 1 auditory receptor cell morphogenesis 2 antigen processing and presentation 1 axolemma 2 apoptotic chromosome condensation 1 axon extension 2 apoptotic DNA fragmentation 1 B-1 B cell homeostasis 2 apoptotic process involved in morphogenesis 1 B cell activation 2 arachidonic acid metabolic process 1 B cell lineage commitment 2 arachidonic acid secretion 1 B cell mediated immunity 2 arginine catabolic process 1 B cell proliferation 2 arginine metabolic process 1 barbed-end actin filament capping 2 asparagine biosynthetic process 1 base-excision repair, gap-filling 2 aspartyl-tRNA aminoacylation 1 beta-amyloid clearance 2 astrocyte cell migration 1 bile acid biosynthetic process 2 astrocyte development 1 biotin metabolic process 2 ATP synthesis coupled electron transport 1 blastocyst development 2 atrioventricular valve morphogenesis 1 blood vessel endothelial cell migration 2 attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation 1 BMP signaling pathway 2 axon cargo transport 1 bundle of His cell to Purkinje myocyte communication 2 axon ensheathment 1 calcium-dependent cysteine-type endopeptidase activity 2 axon regeneration 1 calcium-mediated signaling 2 axon target recognition 1 calcium channel activity 2 axon transport of mitochondrion 1 calcium ion transmembrane transport 2 B cell cytokine production 1 calcium ion transport 2 B cell receptor signaling pathway 1 cAMP-dependent protein kinase regulator activity 2 base-excision repair, AP site formation 1 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity 2 base conversion or substitution editing 1 carbohydrate phosphorylation 2 basement membrane assembly 1 carboxy-lyase activity 2 behavioral fear response 1 carboxylic acid metabolic process 2 behavioral response to ethanol 1 cardiac muscle cell action potential 2 behavioral response to starvation 1 cardiac muscle cell differentiation 2 Bergmann glial cell differentiation 1 cardiac muscle fiber development 2 bicarbonate transport 1 cardiac muscle tissue morphogenesis 2 bile acid and bile salt transport 1 cardiolipin acyl-chain remodeling 2 bioluminescence 1 carnitine metabolic process, CoA-linked 2 blastocyst formation 1 catalase activity 2 blood vessel development 1 catenin complex 2 blood vessel maturation 1 CatSper complex 2 blood vessel morphogenesis 1 cell adhesion molecule binding 2 branching involved in labyrinthine layer morphogenesis 1 cell communication by electrical coupling involved in cardiac conduction 2 branching involved in prostate gland morphogenesis 1 cell differentiation involved in embryonic placenta development 2 branchiomotor neuron axon guidance 1 cellular glucose homeostasis 2 C-5 methylation of cytosine 1 cellular hyperosmotic salinity response 2 CAAX-box protein processing 1 cellular hypotonic response 2 Cajal body organization 1 cellular iron ion homeostasis 2 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules 1 cellular potassium ion homeostasis 2 cAMP-mediated signaling 1 cellular respiration 2 cap-independent translational initiation 1 cellular response to ATP 2 carbamoyl phosphate biosynthetic process 1 cellular response to cadmium ion 2 cardiac chamber development 1 cellular response to dexamethasone stimulus 2 cardiac muscle hypertrophy 1 cellular response to drug 2 cardiovascular system development 1 cellular response to fatty acid 2 carnitine biosynthetic process 1 cellular response to glucagon stimulus 2 carnitine metabolic process 1 cellular response to glucocorticoid stimulus 2 carnitine shuttle 1 cellular response to glucose starvation 2 cation transmembrane transport 1 cellular response to hydroxyurea 2 caveolin-mediated endocytosis 1 cellular response to indole-3-methanol 2 cell-cell signaling involved in cell-cell junction organization 1 cellular response to interferon-alpha 2 cell competition in a multicellular organism 1 cellular response to lipopolysaccharide 2 cell cycle checkpoint 1 cellular response to morphine 2 cell envelope organization 1 cellular response to retinoic acid 2 cell fate specification 1 cellular response to transforming growth factor beta stimulus 2 cell migration involved in gastrulation 1 cellular response to X-ray 2 cell morphogenesis involved in differentiation 1 cellular sodium ion homeostasis 2 cell morphogenesis involved in neuron differentiation 1 cellular triglyceride homeostasis 2 cell projection organization 1 centromeric DNA binding 2 cell proliferation in forebrain 1 centrosome cycle 2 cellular calcium ion homeostasis 1 ceramide metabolic process 2 cellular chemical homeostasis 1 cerebellum development 2 cellular chloride ion homeostasis 1 chemotaxis 2 cellular defense response 1 cholesterol homeostasis 2 cellular heat acclimation 1 chromatin DNA binding 2 cellular response to caffeine 1 chromo shadow domain binding 2 cellular response to cAMP 1 ciliary rootlet 2 cellular response to cell-matrix adhesion 1 circulatory system process 2 cellular response to cytokine stimulus 1 cis assembly of pre-catalytic spliceosome 2 cellular response to estradiol stimulus 1 citrate (Si)-synthase activity 2 cellular response to ethanol 1 clathrin-mediated endocytosis 2 cellular response to extracellular stimulus 1 clathrin adaptor complex 2 cellular response to fibroblast growth factor stimulus 1 clathrin coat 2 cellular response to fluid shear stress 1 clathrin coat of coated pit 2 cellular response to freezing 1 clathrin coat of trans-Golgi network vesicle 2 cellular response to glucose stimulus 1 co-SMAD binding 2 cellular response to granulocyte macrophage colony-stimulating factor stimulus 1 coated vesicle 2 cellular response to growth factor stimulus 1 cochlear nucleus development 2 cellular response to hormone stimulus 1 collagen fibril organization 2 cellular response to interferon-beta 1 condensed nuclear chromosome outer kinetochore 2 cellular response to interleukin-1 1 COPI coating of Golgi vesicle 2 cellular response to iron(III) ion 1 COPI vesicle coat 2 cellular response to platelet-derived growth factor stimulus 1 core promoter sequence-specific DNA binding 2 cellular response to potassium ion 1 CRD-mediated mRNA stability complex 2 cellular response to superoxide 1 CRD-mediated mRNA stabilization 2 cellular response to tumor necrosis factor 1 CTP biosynthetic process 2 cellular response to vascular endothelial growth factor stimulus 1 Cul2-RING ubiquitin ligase complex 2 central nervous system projection neuron axonogenesis 1 CUT catabolic process 2 centriole replication 1 cuticular plate 2 centrosome organization 1 cyclin-dependent protein kinase holoenzyme complex 2 cerebellar cortex development 1 cyclin-dependent protein serine/threonine kinase activity 2 cerebellar cortex structural organization 1 cysteine-type endopeptidase inhibitor activity 2 cerebellar Purkinje cell differentiation 1 cytoplasm organization 2 cerebellar Purkinje cell layer development 1 cytoplasmic dynein complex 2 cerebellar Purkinje cell layer morphogenesis 1 cytoplasmic ribonucleoprotein granule 2 cerebral cortex development 1 cytoplasmic sequestering of NF-kappaB 2 chaperone-mediated protein transport 1 cytoplasmic sequestering of protein 2 chaperone cofactor-dependent protein refolding 1 cytoskeletal anchoring at plasma membrane 2 chaperone mediated protein folding requiring cofactor 1 D-alanine-D-alanine ligase activity 2 chemokine production 1 DBIRD complex 2 chloride transmembrane transport 1 deacetylase activity 2 chloride transport 1 defense response to Gram-positive bacterium 2 cholesterol biosynthetic process 1 dendrite development 2 chorismate metabolic process 1 deoxyribonucleotide biosynthetic process 2 chromatin assembly 1 desmosome assembly 2 chromatin silencing 1 desmosome organization 2 chromatin silencing at rDNA 1 detection of chemical stimulus involved in sensory perception of bitter taste 2 chromatin silencing at telomere 1 determination of left/right symmetry 2 chromosome condensation 1 dihydrolipoyllysine-residue acetyltransferase activity 2 chromosome passenger complex localization to kinetochore 1 dihydroorotase activity 2 chromosome separation 1 DNA-dependent DNA replication 2 chronic inflammatory response 1 DNA-dependent protein kinase activity 2 chronic inflammatory response to antigenic stimulus 1 DNA-directed RNA polymerase III complex 2 circadian behavior 1 DNA (cytosine-5-)-methyltransferase activity 2 circadian regulation of translation 1 DNA biosynthetic process 2 circadian sleep/wake cycle 1 DNA catabolic process 2 circadian sleep/wake cycle, non-REM sleep 1 DNA damage induced protein phosphorylation 2 citrulline biosynthetic process 1 DNA dealkylation involved in DNA repair 2 clathrin coat assembly 1 DNA packaging 2 cleavage furrow formation 1 DNA replication-dependent nucleosome assembly 2 cochlea development 1 DNA replication factor C complex 2 coenzyme A metabolic process 1 DNA replication origin binding 2 collagen biosynthetic process 1 DNA replication proofreading 2 collagen catabolic process 1 DNA strand renaturation 2 collagen metabolic process 1 dolichyl-diphosphooligosaccharide-protein glycotransferase activity 2 common-partner SMAD protein phosphorylation 1 dorsal/ventral pattern formation 2 convergent extension involved in axis elongation 1 dosage compensation by inactivation of X chromosome 2 cornification 1 double-stranded RNA adenosine deaminase activity 2 coronary artery morphogenesis 1 double-stranded telomeric DNA binding 2 corpus callosum development 1 drug metabolic process 2 cortical actin cytoskeleton organization 1 dynein complex 2 creatine metabolic process 1 ectoderm development 2 cristae formation 1 embryonic cleavage 2 cyclic nucleotide catabolic process 1 embryonic limb morphogenesis 2 cyclin catabolic process 1 embryonic skeletal system development 2 cytokine production involved in inflammatory response 1 endocrine pancreas development 2 cytoplasmic translational initiation 1 endonuclease activity 2 cytosine metabolic process 1 endopeptidase inhibitor activity 2 cytosolic calcium ion homeostasis 1 endoplasmic reticulum organization 2 D-gluconate metabolic process 1 endosome organization 2 dATP catabolic process 1 enoyl-CoA hydratase activity 2 deadenylation-dependent decapping of nuclear-transcribed mRNA 1 enzyme activator activity 2 death 1 enzyme inhibitor activity 2 decidualization 1 ephrin receptor signaling pathway 2 defense response 1 epidermal growth factor receptor binding 2 defense response to bacterium 1 epithelial cell-cell adhesion 2 defense response to fungus 1 epithelial tube branching involved in lung morphogenesis 2 definitive hemopoiesis 1 ERK1 and ERK2 cascade 2 dendrite morphogenesis 1 erythrocyte development 2 dendritic cell chemotaxis 1 ESC/E(Z) complex 2 dendritic cell proliferation 1 establishment of integrated proviral latency 2 dendritic spine maintenance 1 establishment of skin barrier 2 depurination 1 establishment or maintenance of microtubule cytoskeleton polarity 2 detection of calcium ion 1 estrogen receptor binding 2 detection of mechanical stimulus 1 eukaryotic initiation factor 4E binding 2 detection of muscle stretch 1 eukaryotic translation initiation factor 2 complex 2 detection of UV 1 exit from mitosis 2 developmental maturation 1 external side of plasma membrane 2 dGTP catabolic process 1 extracellular matrix disassembly 2 diadenosine tetraphosphate biosynthetic process 1 extrinsic apoptotic signaling pathway 2 dicarboxylic acid catabolic process 1 fatty acid beta-oxidation using acyl-CoA dehydrogenase 2 dicarboxylic acid transport 1 fatty acid beta-oxidation using acyl-CoA oxidase 2 digestive tract development 1 fatty acid metabolic process 2 DNA catabolic process, endonucleolytic 1 fatty acid synthase activity 2 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator 1 female pregnancy 2 DNA double-strand break processing 1 female pronucleus 2 DNA ligation 1 ferrochelatase activity 2 DNA methylation involved in embryo development 1 FK506 binding 2 DNA methylation involved in gamete generation 1 folic acid-containing compound biosynthetic process 2 DNA replication checkpoint 1 four-way junction DNA binding 2 DNA replication, removal of RNA primer 1 fructose-bisphosphate aldolase activity 2 DNA rewinding 1 fructose metabolic process 2 dolichol-linked oligosaccharide biosynthetic process 1 fucose metabolic process 2 dorsal/ventral neural tube patterning 1 G-protein coupled receptor activity 2 early endosome to late endosome transport 1 G-quadruplex DNA binding 2 eating behavior 1 G-quadruplex RNA binding 2 ectopic germ cell programmed cell death 1 galactokinase activity 2 elastic fiber assembly 1 galactose metabolic process 2 embryo development ending in birth or egg hatching 1 galactosylceramidase activity 2 embryonic forelimb morphogenesis 1 galactosylceramide catabolic process 2 embryonic hemopoiesis 1 gamma-aminobutyric acid signaling pathway 2 embryonic hindlimb morphogenesis 1 gamma-catenin binding 2 embryonic placenta morphogenesis 1 gamma-glutamyltransferase activity 2 embryonic skeletal system morphogenesis 1 gap junction 2 endochondral bone morphogenesis 1 glucose-6-phosphate dehydrogenase activity 2 endoderm development 1 glucose 6-phosphate metabolic process 2 endoderm formation 1 glutamate-5-semialdehyde dehydrogenase activity 2 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1 glutamate-tRNA ligase activity 2 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1 glutamate 5-kinase activity 2 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1 glutamine-tRNA ligase activity 2 endoplasmic reticulum membrane fusion 1 glutaminyl-tRNA aminoacylation 2 endosomal vesicle fusion 1 glutathione binding 2 endosome localization 1 glutathione peroxidase activity 2 endosome to lysosome transport 1 glycerophospholipid biosynthetic process 2 endothelial cell-cell adhesion 1 glycine-tRNA ligase activity 2 endothelial cell morphogenesis 1 glycine hydroxymethyltransferase activity 2 endothelial tube morphogenesis 1 glycine metabolic process 2 entrainment of circadian clock 1 glycogen debranching enzyme activity 2 entrainment of circadian clock by photoperiod 1 glycogen phosphorylase activity 2 enzyme-directed rRNA 2'-O-methylation 1 glycogen synthase activity, transferring glucose-1-phosphate 2 epidermis morphogenesis 1 glycoside catabolic process 2 epithelial cell maturation 1 glycosphingolipid metabolic process 2 epithelial cell maturation involved in prostate gland development 1 glycosylceramide catabolic process 2 epithelial cell migration 1 GMP biosynthetic process 2 ER overload response 1 GMP synthase activity 2 ERBB signaling pathway 1 Golgi stack 2 erythrocyte maturation 1 Golgi to plasma membrane protein transport 2 establishment of apical/basal cell polarity 1 GTPase activating protein binding 2 establishment of blood-nerve barrier 1 guanylate kinase activity 2 establishment of cell polarity 1 H3 histone acetyltransferase activity 2 establishment of cell polarity involved in ameboidal cell migration 1 H4 histone acetyltransferase activity 2 establishment of chromatin silencing 1 heart contraction 2 establishment of glial blood-brain barrier 1 heme biosynthetic process 2 establishment of meiotic spindle localization 1 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules 2 establishment of neuroblast polarity 1 histidine catabolic process 2 establishment of nucleus localization 1 histone acetyltransferase activity (H4-K16 specific) 2 establishment of planar polarity 1 histone acetyltransferase activity (H4-K5 specific) 2 establishment of protein localization to chromatin 1 histone acetyltransferase activity (H4-K8 specific) 2 establishment of protein localization to plasma membrane 1 histone deacetylation 2 establishment of protein localization to vacuole 1 histone demethylase activity (H3-dimethyl-K4 specific) 2 establishment of spindle orientation 1 histone demethylase activity (H3-K36 specific) 2 establishment of T cell polarity 1 histone demethylase activity (H3-K4 specific) 2 establishment or maintenance of epithelial cell apical/basal polarity 1 histone demethylase activity (H3-monomethyl-K4 specific) 2 estrogen metabolic process 1 histone H3-K36 demethylation 2 estrous cycle phase 1 histone H3-R17 methylation 2 exosomal secretion 1 histone H4-K16 acetylation 2 extracellular amino acid transport 1 histone H4-K5 acetylation 2 extrinsic apoptotic signaling pathway in absence of ligand 1 histone H4-K8 acetylation 2 extrinsic apoptotic signaling pathway via death domain receptors 1 histone kinase activity (H3-T11 specific) 2 eye pigmentation 1 histone locus body 2 face morphogenesis 1 histone methylation 2 fat cell differentiation 1 histone methyltransferase activity 2 female gamete generation 1 histone methyltransferase activity (H3-R17 specific) 2 female meiosis I 1 histone mRNA catabolic process 2 fibroblast migration 1 histone pre-mRNA 3'end processing complex 2 filopodium assembly 1 Hsp70 protein binding 2 focal adhesion assembly 1 hydrogen peroxide biosynthetic process 2 folic acid-containing compound metabolic process 1 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 2 folic acid metabolic process 1 hydrolase activity, acting on ester bonds 2 forebrain morphogenesis 1 hydrolase activity, hydrolyzing O-glycosyl compounds 2 formate metabolic process 1 immunological synapse 2 forward locomotion 1 insulin-like growth factor receptor binding 2 fourth ventricle development 1 insulin secretion 2 fructose 1,6-bisphosphate metabolic process 1 integrin binding 2 fructose 6-phosphate metabolic process 1 intercellular bridge 2 G-protein coupled acetylcholine receptor signaling pathway 1 intermediate filament bundle assembly 2 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger 1 internal protein amino acid acetylation 2 galactitol metabolic process 1 intra-S DNA damage checkpoint 2 galactose catabolic process 1 intracellular steroid hormone receptor signaling pathway 2 gap junction assembly 1 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress 2 gastrulation with mouth forming second 1 ion channel inhibitor activity 2 GDP-mannose biosynthetic process 1 isoleucine-tRNA ligase activity 2 gene silencing 1 keratin filament binding 2 germ cell development 1 ketol-acid reductoisomerase activity 2 gliogenesis 1 kinetochore binding 2 glomerular visceral epithelial cell development 1 kinetochore microtubule 2 glossopharyngeal nerve development 1 L-glutamate transmembrane transporter activity 2 glucocorticoid catabolic process 1 leucine import 2 glucose homeostasis 1 ligase activity, forming aminoacyl-tRNA and related compounds 2 glutamate metabolic process 1 lipopolysaccharide-mediated signaling pathway 2 glutamine catabolic process 1 lipopolysaccharide binding 2 glutamine transport 1 long-chain-3-hydroxyacyl-CoA dehydrogenase activity 2 glutamyl-tRNA aminoacylation 1 long-chain fatty-acyl-CoA biosynthetic process 2 glutathione biosynthetic process 1 lung morphogenesis 2 glycerol ether metabolic process 1 Lys63-specific deubiquitinase activity 2 glycine betaine biosynthetic process from choline 1 lysine-acetylated histone binding 2 glycine biosynthetic process 1 lysine catabolic process 2 glycine biosynthetic process from serine 1 lysosomal lumen 2 glycine catabolic process 1 macromolecular complex 2 glycosaminoglycan catabolic process 1 malate-aspartate shuttle 2 glycosphingolipid catabolic process 1 male germ cell nucleus 2 glycyl-tRNA aminoacylation 1 male meiosis 2 Golgi reassembly 1 male meiosis I 2 Golgi ribbon formation 1 mammary gland duct morphogenesis 2 Golgi to endosome transport 1 mannose binding 2 Golgi to lysosome transport 1 MAPK import into nucleus 2 Golgi to plasma membrane CFTR protein transport 1 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 2 GTP biosynthetic process 1 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 2 hair follicle development 1 MDM2/MDM4 family protein binding 2 hair follicle morphogenesis 1 mediator complex binding 2 head development 1 medium-chain-acyl-CoA dehydrogenase activity 2 head morphogenesis 1 medium-chain fatty acid metabolic process 2 heart growth 1 meiotic cell cycle 2 heart morphogenesis 1 meiotic cohesin complex 2 hematopoietic stem cell differentiation 1 meiotic mismatch repair 2 hematopoietic stem cell homeostasis 1 membrane-bounded organelle 2 hematopoietic stem cell proliferation 1 membrane fusion 2 hemoglobin metabolic process 1 membrane protein ectodomain proteolysis 2 hemolysis by symbiont of host erythrocytes 1 membrane repolarization during cardiac muscle cell action potential 2 hemopoiesis 1 metalloexopeptidase activity 2 hepatocyte differentiation 1 methionine-tRNA ligase activity 2 histamine secretion by mast cell 1 MHC class I protein binding 2 histidine biosynthetic process 1 microtubule anchoring 2 histidine catabolic process to glutamate and formamide 1 microtubule anchoring at microtubule organizing center 2 histidine catabolic process to glutamate and formate 1 microtubule bundle formation 2 histone arginine methylation 1 microtubule organizing center organization 2 histone glutamine methylation 1 microtubule plus-end binding 2 histone H2A-T120 phosphorylation 1 microvillus 2 histone H2B conserved C-terminal lysine deubiquitination 1 midbrain development 2 histone H3-K14 acetylation 1 minus-end-directed organelle transport along microtubule 2 histone H3-K4 trimethylation 1 mitochondrial fatty acid beta-oxidation multienzyme complex 2 histone H3-R2 demethylation 1 mitochondrial inner membrane presequence translocase complex 2 histone H3-R2 methylation 1 mitochondrial light strand promoter anti-sense binding 2 histone H3-S10 phosphorylation involved in chromosome condensation 1 mitochondrion morphogenesis 2 histone H3-T11 phosphorylation 1 mitotic chromosome condensation 2 histone H4-K12 acetylation 1 mitotic G1 DNA damage checkpoint 2 histone H4-R3 demethylation 1 mitotic spindle midzone 2 histone mRNA metabolic process 1 MLL5-L complex 2 histone phosphorylation 1 mRNA 3'-splice site recognition 2 homocysteine biosynthetic process 1 mRNA catabolic process 2 hydroxylysine biosynthetic process 1 mRNA cleavage and polyadenylation specificity factor complex 2 I-kappaB kinase/NF-kappaB signaling 1 mRNA splice site selection 2 immunoglobulin V(D)J recombination 1 mRNA stabilization 2 inner cell mass cell proliferation 1 mucosal immune response 2 inner ear morphogenesis 1 MutLalpha complex binding 2 inositol phosphate-mediated signaling 1 MutSbeta complex 2 inositol phosphate metabolic process 1 MyD88-independent toll-like receptor signaling pathway 2 insulin-like growth factor receptor signaling pathway 1 myelin sheath 2 interkinetic nuclear migration 1 myelin sheath abaxonal region 2 intermediate filament-based process 1 myelination 2 intraciliary retrograde transport 1 myeloid cell homeostasis 2 IRES-dependent translational initiation 1 myosin binding 2 iron ion homeostasis 1 myosin filament 2 isoleucyl-tRNA aminoacylation 1 NAD-dependent histone deacetylase activity 2 isotype switching to IgG isotypes 1 NAD-dependent histone deacetylase activity (H3-K9 specific) 2 JAK-STAT cascade 1 NAD-dependent protein deacetylase activity 2 JAK-STAT cascade involved in growth hormone signaling pathway 1 NAD(P)H oxidase activity 2 JNK cascade 1 NADH dehydrogenase (ubiquinone) activity 2 keratinocyte activation 1 nBAF complex 2 keratinocyte migration 1 NEDD8-specific protease activity 2 keratinocyte proliferation 1 negative regulation of actin filament depolymerization 2 L-alanine catabolic process 1 negative regulation of angiogenesis 2 L-alanine metabolic process 1 negative regulation of apoptotic signaling pathway 2 L-glutamate transport 1 negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process 2 L-phenylalanine catabolic process 1 negative regulation of B cell activation 2 L-serine biosynthetic process 1 negative regulation of beta-amyloid formation 2 L-serine metabolic process 1 negative regulation of cAMP-dependent protein kinase activity 2 L-serine transport 1 negative regulation of cardiac muscle hypertrophy 2 labyrinthine layer blood vessel development 1 negative regulation of cell death 2 lactate metabolic process 1 negative regulation of cell differentiation 2 lactation 1 negative regulation of cell migration 2 lamellipodium assembly 1 negative regulation of circadian rhythm 2 late endosome to Golgi transport 1 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process 2 lens development in camera-type eye 1 negative regulation of cytosolic calcium ion concentration 2 lens fiber cell development 1 negative regulation of defense response to virus 2 leucine catabolic process 1 negative regulation of dendrite morphogenesis 2 leukocyte chemotaxis 1 negative regulation of DNA damage response, signal transduction by p53 class mediator 2 leukocyte migration involved in inflammatory response 1 negative regulation of DNA endoreduplication 2 leukotriene biosynthetic process 1 negative regulation of DNA recombination at telomere 2 limb morphogenesis 1 negative regulation of epithelial cell proliferation 2 lipid biosynthetic process 1 negative regulation of fibroblast proliferation 2 lipid homeostasis 1 negative regulation of focal adhesion assembly 2 lipid particle organization 1 negative regulation of heart contraction 2 lipid tube assembly 1 negative regulation of helicase activity 2 lipopolysaccharide biosynthetic process 1 negative regulation of hydrogen peroxide-induced neuron death 2 lipoprotein transport 1 negative regulation of inflammatory response 2 lipoxygenase pathway 1 negative regulation of innate immune response 2 long-chain fatty acid biosynthetic process 1 negative regulation of interleukin-6 production 2 long-term memory 1 negative regulation of intracellular estrogen receptor signaling pathway 2 lung lobe morphogenesis 1 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 2 lymphocyte differentiation 1 negative regulation of JNK cascade 2 lymphocyte proliferation 1 negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process 2 macrophage activation 1 negative regulation of mitotic cell cycle 2 macrophage differentiation 1 negative regulation of neuroblast proliferation 2 maintenance of chromatin silencing 1 negative regulation of neurofibrillary tangle assembly 2 maintenance of DNA repeat elements 1 negative regulation of neurogenesis 2 maintenance of mitochondrion location 1 negative regulation of neuron projection development 2 male germ cell proliferation 1 negative regulation of NF-kappaB import into nucleus 2 malonyl-CoA biosynthetic process 1 negative regulation of nitric oxide biosynthetic process 2 mammary gland epithelial cell proliferation 1 negative regulation of osteoblast differentiation 2 mammary gland involution 1 negative regulation of peptidase activity 2 mast cell degranulation 1 negative regulation of peptidyl-cysteine S-nitrosylation 2 maturation of 5.8S rRNA 1 negative regulation of peptidyl-serine phosphorylation 2 medium-chain fatty-acyl-CoA metabolic process 1 negative regulation of peroxisome proliferator activated receptor signaling pathway 2 medium-chain fatty acid catabolic process 1 negative regulation of phosphatidylinositol 3-kinase signaling 2 meiosis I 1 negative regulation of phosphorylation 2 meiotic gene conversion 1 negative regulation of platelet-derived growth factor receptor-beta signaling pathway 2 meiotic spindle organization 1 negative regulation of potassium ion transmembrane transport 2 melanocyte differentiation 1 negative regulation of potassium ion transmembrane transporter activity 2 membrane assembly 1 negative regulation of programmed cell death 2 membrane depolarization during action potential 1 negative regulation of prostaglandin biosynthetic process 2 membrane depolarization during cardiac muscle cell action potential 1 negative regulation of protein refolding 2 membrane hyperpolarization 1 negative regulation of protein serine/threonine kinase activity 2 membrane invagination 1 negative regulation of release of cytochrome c from mitochondria 2 membrane repolarization 1 negative regulation of retinoic acid receptor signaling pathway 2 mesoderm development 1 negative regulation of RNA export from nucleus 2 metaphase/anaphase transition of mitotic cell cycle 1 negative regulation of rubidium ion transmembrane transporter activity 2 metencephalon development 1 negative regulation of rubidium ion transport 2 methionine biosynthetic process 1 negative regulation of smooth muscle cell migration 2 methionyl-tRNA aminoacylation 1 negative regulation of substrate adhesion-dependent cell spreading 2 methylation-dependent chromatin silencing 1 negative regulation of tau-protein kinase activity 2 microtubule depolymerization 1 negative regulation of telomeric RNA transcription from RNA pol II promoter 2 microtubule nucleation 1 negative regulation of TOR signaling 2 middle ear morphogenesis 1 negative regulation of tumor necrosis factor production 2 miRNA metabolic process 1 negative regulation of tyrosine phosphorylation of Stat3 protein 2 mitochondrial calcium ion homeostasis 1 negative regulation of ubiquitin-protein transferase activity 2 mitochondrial DNA metabolic process 1 negative regulation of vascular permeability 2 mitochondrial DNA repair 1 negative regulation of viral release from host cell 2 mitochondrial electron transport, NADH to ubiquinone 1 neurexin family protein binding 2 mitochondrial fragmentation involved in apoptotic process 1 neurofilament cytoskeleton organization 2 mitochondrial genome maintenance 1 neuromuscular junction development 2 mitochondrial membrane organization 1 neuromuscular process 2 mitochondrial protein processing 1 neuron apoptotic process 2 mitochondrial respiratory chain complex assembly 1 neuron death 2 mitochondrial respiratory chain complex I assembly 1 neuron projection extension 2 mitochondrial RNA 5'-end processing 1 neutral amino acid transport 2 mitochondrial translation 1 neutrophil chemotaxis 2 mitochondrial transport 1 neutrophil homeostasis 2 mitochondrion localization 1 NLS-dependent protein nuclear import complex 2 mitochondrion transport along microtubule 1 npBAF complex 2 mitotic cell cycle arrest 1 nuclear body 2 mitotic centrosome separation 1 nuclear exosome (RNase complex) 2 mitotic spindle stabilization 1 nuclear matrix anchoring at nuclear membrane 2 modulation by virus of host morphology or physiology 1 nuclear ubiquitin ligase complex 2 monocyte differentiation 1 nucleolar ribonuclease P complex 2 monovalent inorganic cation transport 1 nucleolus organization 2 motile cilium assembly 1 nucleoside diphosphate kinase activity 2 motor neuron axon guidance 1 nucleosome 2 mRNA cis splicing, via spliceosome 1 nucleotide-excision repair complex 2 mRNA export from nucleus in response to heat stress 1 nucleotide phosphorylation 2 mRNA modification 1 nucleus organization 2 mRNA transcription from RNA polymerase II promoter 1 oocyte maturation 2 multicellular organismal iron ion homeostasis 1 oogenesis 2 multicellular organismal protein metabolic process 1 organ morphogenesis 2 multivesicular body sorting pathway 1 ossification 2 myoblast fusion 1 oxidation-dependent protein catabolic process 2 myofibril assembly 1 oxidized purine DNA binding 2 myotube cell development 1 oxidoreductase activity, acting on NAD(P)H 2 N-acetylmannosamine metabolic process 1 oxidoreductase activity, acting on peroxide as acceptor 2 N-terminal protein amino acid acetylation 1 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 2 N-terminal protein amino acid modification 1 oxidoreductase activity, acting on the CH-CH group of donors 2 NAD metabolic process 1 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 2 NADH metabolic process 1 oxoglutarate dehydrogenase (succinyl-transferring) activity 2 NADP metabolic process 1 PAN complex 2 NADPH regeneration 1 pentose biosynthetic process 2 nail development 1 peptide binding 2 natural killer cell chemotaxis 1 peptide biosynthetic process 2 ncRNA metabolic process 1 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine 2 negative regulation of adenylate cyclase activity 1 peptidyl-arginine N-methylation 2 negative regulation of alpha-beta T cell proliferation 1 pericentriolar material 2 negative regulation of androgen receptor signaling pathway 1 perikaryon 2 negative regulation of autophagy 1 peripheral nervous system myelin maintenance 2 negative regulation of blood vessel endothelial cell migration 1 phosphatidylinositol-4,5-bisphosphate binding 2 negative regulation of BMP signaling pathway 1 phosphatidylinositol 3-kinase binding 2 negative regulation of bone resorption 1 phosphatidylinositol binding 2 negative regulation of cardiac muscle contraction 1 phospholipase A2 inhibitor activity 2 negative regulation of CD40 signaling pathway 1 phospholipase binding 2 negative regulation of cell-cell adhesion 1 phosphopyruvate hydratase activity 2 negative regulation of cell adhesion involved in substrate-bound cell migration 1 phosphopyruvate hydratase complex 2 negative regulation of cell cycle arrest 1 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity 2 negative regulation of cell motility 1 phosphoribosylformylglycinamidine synthase activity 2 negative regulation of cell proliferation involved in contact inhibition 1 phosphorylase kinase regulator activity 2 negative regulation of cellular component movement 1 phosphoserine binding 2 negative regulation of cellular response to testosterone stimulus 1 phosphotyrosine binding 2 negative regulation of cellular senescence 1 photoreceptor inner segment 2 negative regulation of centrosome duplication 1 pigmentation 2 negative regulation of cholesterol biosynthetic process 1 placenta development 2 negative regulation of chromatin binding 1 plus-end-directed microtubule motor activity 2 negative regulation of chronic inflammatory response 1 polar microtubule 2 negative regulation of collagen binding 1 poly(A)-specific ribonuclease activity 2 negative regulation of cyclic-nucleotide phosphodiesterase activity 1 pore complex assembly 2 negative regulation of defense response to virus by host 1 positive chemotaxis 2 negative regulation of dephosphorylation 1 positive regulation of angiogenesis 2 negative regulation of DNA biosynthetic process 1 positive regulation of attachment of spindle microtubules to kinetochore 2 negative regulation of DNA demethylation 1 positive regulation of blood vessel endothelial cell migration 2 negative regulation of endothelial cell apoptotic process 1 positive regulation of BMP signaling pathway 2 negative regulation of endothelial cell proliferation 1 positive regulation of cAMP-dependent protein kinase activity 2 negative regulation of epithelial to mesenchymal transition 1 positive regulation of canonical Wnt signaling pathway 2 negative regulation of establishment of protein localization to plasma membrane 1 positive regulation of cell-matrix adhesion 2 negative regulation of estrogen receptor binding 1 positive regulation of cell aging 2 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand 1 positive regulation of cell cycle arrest 2 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors 1 positive regulation of cellular component movement 2 negative regulation of fatty acid biosynthetic process 1 positive regulation of choline O-acetyltransferase activity 2 negative regulation of fibroblast apoptotic process 1 positive regulation of circadian rhythm 2 negative regulation of G-protein coupled receptor protein signaling pathway 1 positive regulation of cyclic-nucleotide phosphodiesterase activity 2 negative regulation of G1/S transition of mitotic cell cycle 1 positive regulation of cytokinesis 2 negative regulation of G2/M transition of mitotic cell cycle 1 positive regulation of dipeptide transmembrane transport 2 negative regulation of glucocorticoid biosynthetic process 1 positive regulation of DNA-templated transcription, elongation 2 negative regulation of glucokinase activity 1 positive regulation of epithelial cell proliferation 2 negative regulation of granulocyte differentiation 1 positive regulation of fibroblast proliferation 2 negative regulation of heart induction by canonical Wnt signaling pathway 1 positive regulation of G2/M transition of mitotic cell cycle 2 negative regulation of histone acetylation 1 positive regulation of granulocyte differentiation 2 negative regulation of histone deacetylation 1 positive regulation of histone deacetylation 2 negative regulation of histone H3-K9 methylation 1 positive regulation of histone H3-K4 methylation 2 negative regulation of hyaluronan biosynthetic process 1 positive regulation of inclusion body assembly 2 negative regulation of inclusion body assembly 1 positive regulation of interferon-beta production 2 negative regulation of insulin secretion 1 positive regulation of interferon-gamma production 2 negative regulation of insulin secretion involved in cellular response to glucose stimulus 1 positive regulation of interleukin-1 beta production 2 negative regulation of integrin-mediated signaling pathway 1 positive regulation of intracellular protein transport 2 negative regulation of interleukin-1 beta production 1 positive regulation of lipid transport 2 negative regulation of interleukin-2 production 1 positive regulation of macrophage apoptotic process 2 negative regulation of interleukin-8 production 1 positive regulation of mRNA 3'-end processing 2 negative regulation of interleukin-8 secretion 1 positive regulation of muscle cell differentiation 2 negative regulation of intrinsic apoptotic signaling pathway 1 positive regulation of neurogenesis 2 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator 1 positive regulation of neuron apoptotic process 2 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage 1 positive regulation of neuron projection development 2 negative regulation of ion transmembrane transport 1 positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 2 negative regulation of JAK-STAT cascade 1 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening 2 negative regulation of JUN kinase activity 1 positive regulation of nuclear cell cycle DNA replication 2 negative regulation of lymphocyte differentiation 1 positive regulation of osteoclast differentiation 2 negative regulation of macromitophagy 1 positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway 2 negative regulation of MAPK cascade 1 positive regulation of pathway-restricted SMAD protein phosphorylation 2 negative regulation of microtubule depolymerization 1 positive regulation of phosphatidylinositol 3-kinase signaling 2 negative regulation of microtubule polymerization 1 positive regulation of pinocytosis 2 negative regulation of microtubule polymerization or depolymerization 1 positive regulation of potassium ion transport 2 negative regulation of mitochondrial RNA catabolic process 1 positive regulation of protein autophosphorylation 2 negative regulation of mitosis 1 positive regulation of protein complex assembly 2 negative regulation of mitotic anaphase-promoting complex activity 1 positive regulation of protein export from nucleus 2 negative regulation of multicellular organism growth 1 positive regulation of protein import into nucleus, translocation 2 negative regulation of muscle cell differentiation 1 positive regulation of protein kinase activity 2 negative regulation of neuron differentiation 1 positive regulation of protein oligomerization 2 negative regulation of neuron projection regeneration 1 positive regulation of protein secretion 2 negative regulation of Notch signaling pathway 1 positive regulation of protein ubiquitination 2 negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway 1 positive regulation of Ras GTPase activity 2 negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway 1 positive regulation of reactive oxygen species metabolic process 2 negative regulation of osteoclast proliferation 1 positive regulation of response to DNA damage stimulus 2 negative regulation of peptidyl-lysine acetylation 1 positive regulation of retinoic acid receptor signaling pathway 2 negative regulation of peptidyl-serine dephosphorylation 1 positive regulation of RIG-I signaling pathway 2 negative regulation of peptidyl-threonine phosphorylation 1 positive regulation of signal transduction 2 negative regulation of phagocytosis 1 positive regulation of sodium ion transmembrane transporter activity 2 negative regulation of phospholipase A2 activity 1 positive regulation of synaptic transmission, GABAergic 2 negative regulation of post-translational protein modification 1 positive regulation of T cell activation 2 negative regulation of protein deubiquitination 1 positive regulation of thymocyte apoptotic process 2 negative regulation of protein glutathionylation 1 positive regulation of transcription factor import into nucleus 2 negative regulation of protein homooligomerization 1 positive regulation of transcription from RNA polymerase I promoter 2 negative regulation of protein localization to nucleus 1 positive regulation of transcription from RNA polymerase III promoter 2 negative regulation of protein localization to plasma membrane 1 positive regulation of tumor necrosis factor biosynthetic process 2 negative regulation of protein oligomerization 1 postreplication repair 2 negative regulation of protein polymerization 1 PR-DUB complex 2 negative regulation of protein processing 1 preribosome, large subunit precursor 2 negative regulation of protein secretion 1 presynaptic membrane 2 negative regulation of protein targeting to membrane 1 procollagen-lysine 5-dioxygenase activity 2 negative regulation of protein tyrosine kinase activity 1 procollagen glucosyltransferase activity 2 negative regulation of proteolysis 1 profilin binding 2 negative regulation of Ras GTPase activity 1 programmed cell death 2 negative regulation of Ras protein signal transduction 1 proline-tRNA ligase activity 2 negative regulation of reactive oxygen species metabolic process 1 pronucleus 2 negative regulation of receptor binding 1 proteasomal protein catabolic process 2 negative regulation of receptor internalization 1 proteasome assembly 2 negative regulation of reciprocal meiotic recombination 1 proteasome regulatory particle, base subcomplex 2 negative regulation of Rho-dependent protein serine/threonine kinase activity 1 protein-arginine omega-N asymmetric methyltransferase activity 2 negative regulation of Rho protein signal transduction 1 protein-glutamine gamma-glutamyltransferase activity 2 negative regulation of RNA interference 1 protein ADP-ribosylation 2 negative regulation of RNA splicing 1 protein anchor 2 negative regulation of ryanodine-sensitive calcium-release channel activity 1 protein complex scaffold 2 negative regulation of smooth muscle cell differentiation 1 protein deacetylase activity 2 negative regulation of smooth muscle cell proliferation 1 protein deacetylation 2 negative regulation of smoothened signaling pathway 1 protein deneddylation 2 negative regulation of stress-activated MAPK cascade 1 protein disulfide isomerase activity 2 negative regulation of striated muscle contraction 1 protein disulfide oxidoreductase activity 2 negative regulation of striated muscle tissue development 1 protein glycosylation 2 negative regulation of synaptic transmission 1 protein hexamerization 2 negative regulation of T cell apoptotic process 1 protein import into mitochondrial outer membrane 2 negative regulation of T cell differentiation 1 protein K11-linked ubiquitination 2 negative regulation of telomere maintenance 1 protein K29-linked deubiquitination 2 negative regulation of toll-like receptor 2 signaling pathway 1 protein K33-linked deubiquitination 2 negative regulation of toll-like receptor 3 signaling pathway 1 protein K48-linked ubiquitination 2 negative regulation of toll-like receptor 4 signaling pathway 1 protein kinase CK2 complex 2 negative regulation of toll-like receptor 5 signaling pathway 1 protein kinase regulator activity 2 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia 1 protein localization to cell surface 2 negative regulation of translation in response to stress 1 protein methyltransferase activity 2 negative regulation of translational elongation 1 protein neddylation 2 negative regulation of transmembrane transport 1 protein O-GlcNAc transferase activity 2 negative regulation of transporter activity 1 protein phosphatase inhibitor activity 2 negative regulation of triglyceride catabolic process 1 protein poly-ADP-ribosylation 2 negative regulation of type I interferon-mediated signaling pathway 1 protein retention in Golgi apparatus 2 negative regulation of viral transcription 1 protein self-association 2 negative regulation of Wnt signaling pathway involved in heart development 1 protein serine/threonine kinase activator activity 2 nerve development 1 protein sumoylation 2 neural tube patterning 1 proteinaceous extracellular matrix 2 neuroendocrine cell differentiation 1 proton-transporting ATPase activity, rotational mechanism 2 neuron projection morphogenesis 1 proton-transporting two-sector ATPase complex, catalytic domain 2 neuronal action potential 1 protoporphyrinogen IX metabolic process 2 neurotransmitter receptor metabolic process 1 purine nucleobase biosynthetic process 2 neurotransmitter uptake 1 pyridoxal kinase activity 2 neutrophil aggregation 1 pyrimidine dimer repair by nucleotide-excision repair 2 neutrophil clearance 1 pyrimidine nucleobase metabolic process 2 neutrophil extravasation 1 pyrimidine nucleotide biosynthetic process 2 NIK/NF-kappaB signaling 1 R-SMAD binding 2 nitrogen compound metabolic process 1 Ras GTPase activator activity 2 nitrogen cycle metabolic process 1 rDNA binding 2 nose development 1 reactive oxygen species metabolic process 2 nuclear mRNA surveillance 1 receptor internalization 2 nuclear polyadenylation-dependent rRNA catabolic process 1 recycling endosome 2 nuclear retention of unspliced pre-mRNA at the site of transcription 1 regulation of actin cytoskeleton organization 2 nucleologenesis 1 regulation of autophagy 2 nucleoside diphosphate phosphorylation 1 regulation of bile acid biosynthetic process 2 nucleosome mobilization 1 regulation of cardiac muscle cell contraction 2 nucleosome positioning 1 regulation of cell differentiation 2 nucleotide-excision repair, DNA damage recognition 1 regulation of cell growth 2 nucleus localization 1 regulation of cell size 2 olfactory bulb development 1 regulation of cellular response to heat 2 olfactory bulb mitral cell layer development 1 regulation of cholesterol transport 2 olfactory nerve structural organization 1 regulation of chromosome segregation 2 oligodendrocyte apoptotic process 1 regulation of cytokinesis 2 oligodendrocyte development 1 regulation of defense response to virus by host 2 oligodendrocyte differentiation 1 regulation of defense response to virus by virus 2 oligosaccharide metabolic process 1 regulation of DNA-templated transcription, elongation 2 oocyte development 1 regulation of DNA damage checkpoint 2 optic cup formation involved in camera-type eye development 1 regulation of DNA methylation 2 optic nerve development 1 regulation of DNA repair 2 organic acid metabolic process 1 regulation of endodeoxyribonuclease activity 2 ornithine biosynthetic process 1 regulation of gene expression by genetic imprinting 2 outer ear morphogenesis 1 regulation of germinal center formation 2 outflow tract morphogenesis 1 regulation of glucose metabolic process 2 ovulation from ovarian follicle 1 regulation of histone H3-K9 acetylation 2 oxidative phosphorylation 1 regulation of I-kappaB kinase/NF-kappaB signaling 2 oxidative single-stranded RNA demethylation 1 regulation of inclusion body assembly 2 oxidative stress-induced premature senescence 1 regulation of intracellular estrogen receptor signaling pathway 2 pancreatic juice secretion 1 regulation of JNK cascade 2 pantothenate metabolic process 1 regulation of keratinocyte differentiation 2 paraxial mesoderm development 1 regulation of MAPK cascade 2 pathogenesis 1 regulation of mitochondrial membrane permeability 2 pathway-restricted SMAD protein phosphorylation 1 regulation of mitochondrial membrane potential 2 pentose-phosphate shunt, non-oxidative branch 1 regulation of mRNA processing 2 peptidyl-asparagine hydroxylation 1 regulation of muscle contraction 2 peptidyl-aspartic acid hydroxylation 1 regulation of neuron apoptotic process 2 peptidyl-histidine hydroxylation 1 regulation of neuron differentiation 2 peptidyl-lysine acetylation 1 regulation of opioid receptor signaling pathway 2 peptidyl-lysine deacetylation 1 regulation of peroxisome proliferator activated receptor signaling pathway 2 peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine 1 regulation of phospholipase A2 activity 2 peptidyl-methionine modification 1 regulation of phosphorylation 2 peptidyl-proline hydroxylation 1 regulation of proteasomal ubiquitin-dependent protein catabolic process 2 peptidyl-proline hydroxylation to 4-hydroxy-L-proline 1 regulation of protein binding 2 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase 1 regulation of protein deubiquitination 2 peptidyl-serine dephosphorylation 1 regulation of protein localization 2 peptidyl-threonine dephosphorylation 1 regulation of Rap GTPase activity 2 peptidyl-tyrosine phosphorylation 1 regulation of rhodopsin mediated signaling pathway 2 pericardium development 1 regulation of RNA splicing 2 peripheral nervous system development 1 regulation of signal transduction 2 peroxisome fission 1 regulation of skeletal muscle contraction 2 peroxisome organization 1 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion 2 phagocytosis 1 regulation of sodium ion transmembrane transporter activity 2 phagolysosome assembly 1 regulation of stem cell maintenance 2 phosphate ion transmembrane transport 1 regulation of striated muscle contraction 2 phosphatidylinositol-3-phosphate biosynthetic process 1 regulation of transcription from RNA polymerase II promoter in response to hypoxia 2 phosphatidylinositol 3-kinase signaling 1 regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage 2 phosphatidylinositol biosynthetic process 1 regulation of translational fidelity 2 phosphatidylinositol phosphorylation 1 regulation of translational initiation in response to stress 2 photoreceptor cell maintenance 1 regulation of translational termination 2 photoreceptor cell outer segment organization 1 regulation of type I interferon-mediated signaling pathway 2 phytol metabolic process 1 regulation of type I interferon production 2 placenta blood vessel development 1 regulation of viral transcription 2 plasma membrane repair 1 regulation of voltage-gated calcium channel activity 2 platelet-derived growth factor receptor signaling pathway 1 regulation of Wnt signaling pathway 2 platelet formation 1 relaxation of cardiac muscle 2 plus-end-directed vesicle transport along microtubule 1 relaxation of vascular smooth muscle 2 pointed-end actin filament capping 1 release from viral latency 2 polar body extrusion after meiotic divisions 1 release of cytochrome c from mitochondria 2 porphyrin-containing compound biosynthetic process 1 removal of superoxide radicals 2 porphyrin-containing compound metabolic process 1 replication fork processing 2 positive regulation by host of viral genome replication 1 replicative senescence 2 positive regulation of abscisic acid-activated signaling pathway 1 response to amine 2 positive regulation of actin cytoskeleton reorganization 1 response to amphetamine 2 positive regulation of actin filament polymerization 1 response to arsenic-containing substance 2 positive regulation of activin receptor signaling pathway 1 response to cold 2 positive regulation of acute inflammatory response 1 response to epidermal growth factor 2 positive regulation of adaptive immune response 1 response to glucocorticoid 2 positive regulation of astrocyte differentiation 1 response to glucose 2 positive regulation of autophagy 1 response to hyperoxia 2 positive regulation of bone mineralization involved in bone maturation 1 response to interferon-alpha 2 positive regulation of bone resorption 1 response to ischemia 2 positive regulation of cAMP catabolic process 1 response to lead ion 2 positive regulation of cardiac muscle cell apoptotic process 1 response to lithium ion 2 positive regulation of cardiac muscle cell proliferation 1 response to mechanical stimulus 2 positive regulation of catenin import into nucleus 1 response to mercury ion 2 positive regulation of cell cycle process 1 response to metal ion 2 positive regulation of cell death 1 response to methylmercury 2 positive regulation of cell division 1 response to molecule of bacterial origin 2 positive regulation of cellular pH reduction 1 response to nutrient levels 2 positive regulation of cellular protein catabolic process 1 response to other organism 2 positive regulation of cellular senescence 1 response to platinum ion 2 positive regulation of chaperone-mediated protein complex assembly 1 response to radiation 2 positive regulation of cholesterol homeostasis 1 response to salt stress 2 positive regulation of chromatin silencing 1 response to superoxide 2 positive regulation of circadian sleep/wake cycle, non-REM sleep 1 response to testosterone 2 positive regulation of cyclic nucleotide metabolic process 1 response to tumor necrosis factor 2 positive regulation of cyclin-dependent protein serine/threonine kinase activity 1 response to UV-B 2 positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle 1 response to vitamin E 2 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process 1 response to wounding 2 positive regulation of cytokine production 1 retinoic acid receptor binding 2 positive regulation of cytoplasmic mRNA processing body assembly 1 retrograde axon cargo transport 2 positive regulation of cytosolic calcium ion concentration 1 retrograde vesicle-mediated transport, Golgi to ER 2 positive regulation of cytotoxic T cell differentiation 1 retromer complex 2 positive regulation of dephosphorylation 1 rhodopsin mediated signaling pathway 2 positive regulation of DNA-templated transcription, initiation 1 ribonuclease activity 2 positive regulation of DNA binding 1 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor 2 positive regulation of DNA damage checkpoint 1 ribonucleoside binding 2 positive regulation of DNA replication 1 ribose-5-phosphate isomerase activity 2 positive regulation of early endosome to recycling endosome transport 1 ribosomal large subunit biogenesis 2 positive regulation of embryonic development 1 righting reflex 2 positive regulation of endocytic recycling 1 RNA phosphodiester bond hydrolysis, endonucleolytic 2 positive regulation of endothelial cell chemotaxis 1 RNA polymerase binding 2 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway 1 RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript 2 positive regulation of endothelial cell proliferation 1 RNA polymerase II activity 2 positive regulation of ER to Golgi vesicle-mediated transport 1 RNA polymerase II carboxy-terminal domain kinase activity 2 positive regulation of establishment of protein localization to plasma membrane 1 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription 2 positive regulation of exocytosis 1 RNA polymerase II core promoter sequence-specific DNA binding 2 positive regulation of extrinsic apoptotic signaling pathway 1 RNA polymerase II distal enhancer sequence-specific DNA binding 2 positive regulation of gastrulation 1 RNA polymerase II regulatory region sequence-specific DNA binding 2 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter 1 RNA polymerase II repressing transcription factor binding 2 positive regulation of glucose import 1 RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription 2 positive regulation of hair follicle development 1 RNA polymerase III activity 2 positive regulation of heart contraction 1 rRNA (adenine-N6,N6-)-dimethyltransferase activity 2 positive regulation of hepatocyte proliferation 1 rRNA modification 2 positive regulation of heterochromatin assembly 1 S-adenosylmethionine-dependent methyltransferase activity 2 positive regulation of histone acetylation 1 SAGA-type complex 2 positive regulation of histone H3-K27 methylation 1 sarcoplasm 2 positive regulation of histone H3-K27 trimethylation 1 second-messenger-mediated signaling 2 positive regulation of histone H3-K9 methylation 1 seminiferous tubule development 2 positive regulation of histone modification 1 sensory perception of pain 2 positive regulation of histone phosphorylation 1 serine-tRNA ligase activity 2 positive regulation of inflammatory response 1 Sertoli cell development 2 positive regulation of insulin receptor signaling pathway 1 seryl-tRNA aminoacylation 2 positive regulation of interferon-beta biosynthetic process 1 signal transduction in response to DNA damage 2 positive regulation of interleukin-10 production 1 signal transduction involved in DNA damage checkpoint 2 positive regulation of interleukin-12 production 1 single guanine insertion binding 2 positive regulation of interleukin-6 production 1 single thymine insertion binding 2 positive regulation of intracellular estrogen receptor signaling pathway 1 siRNA binding 2 positive regulation of JUN kinase activity 1 skeletal muscle atrophy 2 positive regulation of kinase activity 1 skeletal muscle contraction 2 positive regulation of Lys63-specific deubiquitinase activity 1 skeletal muscle fiber development 2 positive regulation of macrophage activation 1 skeletal muscle myosin thick filament assembly 2 positive regulation of mammary gland epithelial cell proliferation 1 skeletal muscle thin filament assembly 2 positive regulation of MAP kinase activity 1 skeletal system morphogenesis 2 positive regulation of MDA-5 signaling pathway 1 small nucleolar ribonucleoprotein complex 2 positive regulation of meiosis I 1 smooth muscle contraction 2 positive regulation of membrane protein ectodomain proteolysis 1 smoothened signaling pathway 2 positive regulation of MHC class I biosynthetic process 1 snRNA transcription from RNA polymerase II promoter 2 positive regulation of MHC class II biosynthetic process 1 snRNA transcription from RNA polymerase III promoter 2 positive regulation of mitochondrial depolarization 1 sodium ion binding 2 positive regulation of mitochondrial membrane permeability 1 sodium ion export from cell 2 positive regulation of mitotic cell cycle phase transition 1 sperm motility 2 positive regulation of mitotic cell cycle spindle assembly checkpoint 1 sphingolipid biosynthetic process 2 positive regulation of mitotic metaphase/anaphase transition 1 spindle assembly checkpoint 2 positive regulation of monocyte differentiation 1 spindle assembly involved in mitosis 2 positive regulation of mRNA catabolic process 1 spindle midzone 2 positive regulation of multicellular organism growth 1 spindle organization 2 positive regulation of myoblast differentiation 1 spliceosomal snRNP assembly 2 positive regulation of neuron differentiation 1 sprouting angiogenesis 2 positive regulation of neutrophil apoptotic process 1 stem cell division 2 positive regulation of nitric-oxide synthase activity 1 stem cell maintenance 2 positive regulation of NK T cell activation 1 steroid hormone binding 2 positive regulation of peptide secretion 1 stress-activated MAPK cascade 2 positive regulation of peroxisome proliferator activated receptor signaling pathway 1 striated muscle contraction 2 positive regulation of phosphoprotein phosphatase activity 1 substrate-dependent cell migration, cell extension 2 positive regulation of prostaglandin biosynthetic process 1 succinate-CoA ligase (GDP-forming) activity 2 positive regulation of protein binding 1 superoxide dismutase activity 2 positive regulation of protein dephosphorylation 1 superoxide metabolic process 2 positive regulation of protein exit from endoplasmic reticulum 1 synaptonemal complex assembly 2 positive regulation of protein homodimerization activity 1 T-tubule 2 positive regulation of protein homooligomerization 1 T cell lineage commitment 2 positive regulation of protein K63-linked deubiquitination 1 T cell proliferation 2 positive regulation of protein localization to early endosome 1 T cell receptor signaling pathway 2 positive regulation of protein transport 1 telencephalon development 2 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process 1 telomere maintenance via telomerase 2 positive regulation of Rab GTPase activity 1 telomere maintenance via telomere lengthening 2 positive regulation of Rac protein signal transduction 1 telomeric heterochromatin 2 positive regulation of receptor recycling 1 terminal bouton 2 positive regulation of release of cytochrome c from mitochondria 1 termination of RNA polymerase III transcription 2 positive regulation of Rho GTPase activity 1 thyroid hormone receptor binding 2 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly 1 tissue regeneration 2 positive regulation of RNA splicing 1 toll-like receptor 10 signaling pathway 2 positive regulation of ryanodine-sensitive calcium-release channel activity 1 toll-like receptor 2 signaling pathway 2 positive regulation of skeletal muscle tissue development 1 toll-like receptor 3 signaling pathway 2 positive regulation of SMAD protein import into nucleus 1 toll-like receptor 5 signaling pathway 2 positive regulation of smooth muscle cell apoptotic process 1 toll-like receptor 9 signaling pathway 2 positive regulation of smooth muscle cell proliferation 1 toll-like receptor TLR1:TLR2 signaling pathway 2 positive regulation of sodium ion transport 1 toll-like receptor TLR6:TLR2 signaling pathway 2 positive regulation of sodium:proton antiporter activity 1 toxic substance binding 2 positive regulation of stress fiber assembly 1 trans-Golgi network membrane 2 positive regulation of striated muscle contraction 1 transcription elongation from RNA polymerase III promoter 2 positive regulation of superoxide anion generation 1 transcription factor TFTC complex 2 positive regulation of T cell anergy 1 transcription from mitochondrial promoter 2 positive regulation of T cell mediated cytotoxicity 1 transcription regulatory region sequence-specific DNA binding 2 positive regulation of T cell mediated immune response to tumor cell 1 translation release factor activity 2 positive regulation of transcription elongation from RNA polymerase II promoter 1 translesion synthesis 2 positive regulation of transcription regulatory region DNA binding 1 transmembrane receptor protein tyrosine phosphatase activity 2 positive regulation of transforming growth factor beta1 production 1 transmission of nerve impulse 2 positive regulation of translational elongation 1 TRIF-dependent toll-like receptor signaling pathway 2 positive regulation of vasculogenesis 1 triglyceride biosynthetic process 2 positive regulation of vesicle fusion 1 triglyceride mobilization 2 positive regulation of viral entry into host cell 1 tumor necrosis factor-mediated signaling pathway 2 positive regulation of viral release from host cell 1 tumor necrosis factor receptor binding 2 posttranslational protein targeting to membrane 1 type I interferon signaling pathway 2 pro-B cell differentiation 1 U12-type spliceosomal complex 2 production of miRNAs involved in gene silencing by miRNA 1 U2-type spliceosomal complex 2 progesterone receptor signaling pathway 1 U4/U6 snRNP 2 prolactin secretion 1 UDP-glucose:glycoprotein glucosyltransferase activity 2 prolyl-tRNA aminoacylation 1 unconventional myosin complex 2 prostate gland development 1 unsaturated fatty acid metabolic process 2 prostate gland morphogenesis 1 uropod 2 proteasomal ubiquitin-independent protein catabolic process 1 UTP biosynthetic process 2 proteasome regulatory particle assembly 1 valine-tRNA ligase activity 2 protection from non-homologous end joining at telomere 1 vasculogenesis 2 protein autoprocessing 1 VCB complex 2 protein desumoylation 1 ventricular cardiac muscle cell action potential 2 protein deubiquitination involved in ubiquitin-dependent protein catabolic process 1 ventricular compact myocardium morphogenesis 2 protein heterotetramerization 1 ventricular system development 2 protein heterotrimerization 1 vesicle transport along microtubule 2 protein homotrimerization 1 viral penetration into host nucleus 2 protein hydroxylation 1 visual learning 2 protein import into nucleus, translocation 1 visual perception 2 protein initiator methionine removal 1 voltage-gated anion channel activity 2 protein K27-linked deubiquitination 1 WASH complex 2 protein K29-linked ubiquitination 1 white fat cell differentiation 2 protein K33-linked ubiquitination 1 xenobiotic metabolic process 2 protein kinase C-activating G-protein coupled receptor signaling pathway 1 XPC complex 2 protein localization to chromatin 1 'de novo' protein folding 1 protein localization to chromosome, telomeric region 1 'de novo' UMP biosynthetic process 1 protein localization to endoplasmic reticulum 1 [acyl-carrier-protein] S-acetyltransferase activity 1 protein localization to Golgi apparatus 1 [acyl-carrier-protein] S-malonyltransferase activity 1 protein localization to membrane 1 1-phosphatidylinositol-4-phosphate 3-kinase activity 1 protein localization to mitochondrion 1 1-phosphatidylinositol binding 1 protein localization to organelle 1 17-beta-hydroxysteroid dehydrogenase (NAD+) activity 1 protein localization to synapse 1 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity 1 protein localization to tight junction 1 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity 1 protein maturation by protein folding 1 3'-UTR-mediated mRNA destabilization 1 protein metabolic process 1 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity 1 protein O-linked glycosylation 1 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity 1 protein secretion 1 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity 1 protein targeting to ER 1 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity 1 protein transmembrane transport 1 3-oxoacyl-[acyl-carrier-protein] synthase activity 1 protein trimerization 1 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity 1 pulmonary artery morphogenesis 1 5-phosphoribose 1-diphosphate biosynthetic process 1 purine nucleotide catabolic process 1 6-phosphofructo-2-kinase activity 1 pyramidal neuron development 1 90S preribosome 1 pyridoxal 5'-phosphate salvage 1 acetyl-CoA C-acetyltransferase activity 1 pyridoxal phosphate biosynthetic process 1 acetylcholine receptor binding 1 pyrimidine dimer repair 1 acetylglucosaminyltransferase activity 1 pyrimidine nucleoside biosynthetic process 1 acetyltransferase activity 1 pyrimidine nucleoside metabolic process 1 acrosomal membrane 1 pyrimidine nucleotide metabolic process 1 actin filament polymerization 1 pyruvate biosynthetic process 1 actin filament severing 1 radial glia guided migration of Purkinje cell 1 actin monomer binding 1 receptor-mediated virion attachment to host cell 1 actin polymerization or depolymerization 1 receptor clustering 1 actin rod assembly 1 recognition of apoptotic cell 1 actinin binding 1 recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex 1 activating transcription factor binding 1 recycling endosome to Golgi transport 1 activation of adenylate cyclase activity 1 regulation of acetyl-CoA biosynthetic process from pyruvate 1 activation of innate immune response 1 regulation of actin filament polymerization 1 activation of mitotic anaphase-promoting complex activity 1 regulation of apoptotic DNA fragmentation 1 activation of NF-kappaB-inducing kinase activity 1 regulation of ARF protein signal transduction 1 activation of protein kinase A activity 1 regulation of axon extension 1 activation of protein kinase activity 1 regulation of BMP signaling pathway 1 activation of Rap GTPase activity 1 regulation of calcium ion transport 1 actomyosin contractile ring 1 regulation of cardiac muscle contraction 1 adaptive immune response 1 regulation of cargo loading into COPII-coated vesicle 1 adenosine deaminase activity 1 regulation of cell-substrate adhesion 1 adenosine receptor binding 1 regulation of cell adhesion mediated by integrin 1 adenylate cyclase-inhibiting dopamine receptor signaling pathway 1 regulation of cell communication by electrical coupling involved in cardiac conduction 1 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway 1 regulation of cell death 1 adenylate cyclase binding 1 regulation of cell division 1 adiponectin-activated signaling pathway 1 regulation of cell growth by extracellular stimulus 1 ADP-ribosylation factor binding 1 regulation of cell motility 1 adult behavior 1 regulation of cellular response to growth factor stimulus 1 adult feeding behavior 1 regulation of cellular response to hypoxia 1 adult walking behavior 1 regulation of centriole replication 1 aerobic respiration 1 regulation of centrosome duplication 1 aggresome assembly 1 regulation of chemotaxis 1 aldehyde dehydrogenase [NAD(P)+] activity 1 regulation of chloride transport 1 alpha-2A adrenergic receptor binding 1 regulation of chromosome condensation 1 alpha-tubulin binding 1 regulation of cysteine-type endopeptidase activity involved in apoptotic process 1 alpha DNA polymerase:primase complex 1 regulation of cytokine production 1 amino acid transmembrane transport 1 regulation of definitive erythrocyte differentiation 1 amino acid transmembrane transporter activity 1 regulation of dendritic spine morphogenesis 1 aminoacyl-tRNA synthetase multienzyme complex 1 regulation of DNA-dependent DNA replication initiation 1 ammonia-lyase activity 1 regulation of DNA-templated transcription in response to stress 1 AMP-activated protein kinase complex 1 regulation of DNA-templated transcription, initiation 1 AMP binding 1 regulation of DNA binding 1 anaphase-promoting complex binding 1 regulation of early endosome to late endosome transport 1 anchored component of external side of plasma membrane 1 regulation of eIF2 alpha phosphorylation by dsRNA 1 androgen metabolic process 1 regulation of eIF2 alpha phosphorylation by heme 1 androgen receptor binding 1 regulation of endoribonuclease activity 1 angiostatin binding 1 regulation of epidermal cell differentiation 1 angiotensin-activated signaling pathway 1 regulation of epithelial cell proliferation 1 anion transport 1 regulation of establishment of cell polarity 1 ankyrin repeat binding 1 regulation of establishment of planar polarity involved in neural tube closure 1 annealing helicase activity 1 regulation of establishment of protein localization to plasma membrane 1 antigen binding 1 regulation of exit from mitosis 1 antigen processing and presentation 1 regulation of exocytosis 1 apical dendrite 1 regulation of extrinsic apoptotic signaling pathway via death domain receptors 1 apoptotic chromosome condensation 1 regulation of fatty acid beta-oxidation 1 apoptotic DNA fragmentation 1 regulation of fibroblast apoptotic process 1 apoptotic process involved in morphogenesis 1 regulation of gene silencing by miRNA 1 arachidonic acid binding 1 regulation of genetic imprinting 1 arachidonic acid metabolic process 1 regulation of glucocorticoid metabolic process 1 arachidonic acid secretion 1 regulation of gluconeogenesis 1 arginine catabolic process 1 regulation of glycolytic process 1 arginine metabolic process 1 regulation of Golgi inheritance 1 ASAP complex 1 regulation of growth plate cartilage chondrocyte proliferation 1 asparagine biosynthetic process 1 regulation of growth rate 1 asparagine synthase (glutamine-hydrolyzing) activity 1 regulation of heart rate by hormone 1 aspartate-tRNA ligase activity 1 regulation of hemoglobin biosynthetic process 1 aspartate binding 1 regulation of high voltage-gated calcium channel activity 1 aspartyl-tRNA aminoacylation 1 regulation of histone ubiquitination 1 astrocyte cell migration 1 regulation of immune system process 1 astrocyte development 1 regulation of innate immune response 1 ATP-binding cassette (ABC) transporter complex 1 regulation of insulin receptor signaling pathway 1 ATP-dependent 3'-5' DNA helicase activity 1 regulation of integrin biosynthetic process 1 ATP synthesis coupled electron transport 1 regulation of interferon-gamma-mediated signaling pathway 1 ATPase binding 1 regulation of intrinsic apoptotic signaling pathway 1 atrioventricular valve morphogenesis 1 regulation of intrinsic apoptotic signaling pathway by p53 class mediator 1 attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation 1 regulation of ion transmembrane transporter activity 1 AU-rich element binding 1 regulation of JAK-STAT cascade 1 autophagic vacuole 1 regulation of L-arginine import 1 axon cargo transport 1 regulation of long-term neuronal synaptic plasticity 1 axon ensheathment 1 regulation of low-density lipoprotein particle receptor biosynthetic process 1 axon regeneration 1 regulation of macrophage apoptotic process 1 axon target recognition 1 regulation of membrane potential 1 axon transport of mitochondrion 1 regulation of membrane repolarization 1 B cell cytokine production 1 regulation of microtubule-based movement 1 B cell receptor signaling pathway 1 regulation of microtubule-based process 1 BAF-type complex 1 regulation of microtubule cytoskeleton organization 1 basal cortex 1 regulation of miRNA metabolic process 1 basal lamina 1 regulation of mitochondrial DNA replication 1 basal part of cell 1 regulation of mitochondrial membrane permeability involved in apoptotic process 1 base-excision repair, AP site formation 1 regulation of mitochondrial translation 1 base conversion or substitution editing 1 regulation of mitochondrion degradation 1 basement membrane assembly 1 regulation of mitotic cell cycle phase transition 1 behavioral fear response 1 regulation of mitotic cell cycle spindle assembly checkpoint 1 behavioral response to ethanol 1 regulation of mitotic centrosome separation 1 behavioral response to starvation 1 regulation of mitotic metaphase/anaphase transition 1 Bergmann glial cell differentiation 1 regulation of mitotic recombination 1 beta-catenin destruction complex 1 regulation of mitotic sister chromatid separation 1 betaine-aldehyde dehydrogenase activity 1 regulation of mRNA 3'-end processing 1 bHLH transcription factor binding 1 regulation of mRNA stability 1 bicarbonate transport 1 regulation of myotube differentiation 1 bile acid and bile salt transport 1 regulation of neurogenesis 1 bile acid binding 1 regulation of nucleocytoplasmic transport 1 bioluminescence 1 regulation of nucleotide-excision repair 1 biotin carboxylase activity 1 regulation of organ growth 1 blastocyst formation 1 regulation of ossification 1 blood vessel development 1 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway 1 blood vessel maturation 1 regulation of potassium ion transmembrane transporter activity 1 blood vessel morphogenesis 1 regulation of protein autophosphorylation 1 box C/D snoRNP complex 1 regulation of protein complex assembly 1 branching involved in labyrinthine layer morphogenesis 1 regulation of protein exit from endoplasmic reticulum 1 branching involved in prostate gland morphogenesis 1 regulation of protein homodimerization activity 1 branchiomotor neuron axon guidance 1 regulation of protein import into nucleus, translocation 1 brush border 1 regulation of protein kinase A signaling 1 brush border membrane 1 regulation of protein kinase C signaling 1 C-5 methylation of cytosine 1 regulation of protein localization to nucleus 1 C2H2 zinc finger domain binding 1 regulation of protein metabolic process 1 CAAX-box protein processing 1 regulation of protein monoubiquitination 1 Cajal body organization 1 regulation of protein secretion 1 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules 1 regulation of protein targeting to mitochondrion 1 calcium-release channel activity 1 regulation of protein ubiquitination 1 calcium channel complex 1 regulation of Rab GTPase activity 1 calcium ion transmembrane transporter activity 1 regulation of Rac GTPase activity 1 calcium:sodium antiporter activity 1 regulation of Rac protein signal transduction 1 cAMP-dependent protein kinase complex 1 regulation of receptor activity 1 cAMP-dependent protein kinase inhibitor activity 1 regulation of respiratory gaseous exchange by neurological system process 1 cAMP-mediated signaling 1 regulation of ruffle assembly 1 cAMP binding 1 regulation of skeletal muscle fiber development 1 cap-independent translational initiation 1 regulation of smooth muscle cell migration 1 carbamoyl phosphate biosynthetic process 1 regulation of smooth muscle contraction 1 carbonate dehydratase activity 1 regulation of smoothened signaling pathway 1 carboxyl- or carbamoyltransferase activity 1 regulation of spindle assembly involved in mitosis 1 carboxylic acid binding 1 regulation of spindle checkpoint 1 carboxylic ester hydrolase activity 1 regulation of stem cell proliferation 1 carboxypeptidase activity 1 regulation of stress-activated MAPK cascade 1 cardiac chamber development 1 regulation of synaptic vesicle endocytosis 1 cardiac muscle hypertrophy 1 regulation of systemic arterial blood pressure by baroreceptor feedback 1 cardiovascular system development 1 regulation of T cell differentiation in thymus 1 carnitine biosynthetic process 1 regulation of telomere maintenance 1 carnitine metabolic process 1 regulation of thymocyte apoptotic process 1 carnitine shuttle 1 regulation of tissue remodeling 1 cation-transporting ATPase activity 1 regulation of transcription from RNA polymerase I promoter 1 cation binding 1 regulation of transforming growth factor beta receptor signaling pathway 1 cation transmembrane transport 1 regulation of ubiquitin-protein transferase activity 1 caveolin-mediated endocytosis 1 regulation of vascular wound healing 1 Cdc48p-Npl4p-Ufd1p AAA ATPase complex 1 regulation of vasoconstriction 1 cell-cell signaling involved in cell-cell junction organization 1 regulation of vesicle-mediated transport 1 cell-substrate junction 1 regulation of viral process 1 cell competition in a multicellular organism 1 respiratory burst involved in defense response 1 cell cycle checkpoint 1 response to aluminum ion 1 cell envelope organization 1 response to amino acid 1 cell fate specification 1 response to antipsychotic drug 1 cell migration involved in gastrulation 1 response to ATP 1 cell morphogenesis involved in differentiation 1 response to cadmium ion 1 cell morphogenesis involved in neuron differentiation 1 response to caffeine 1 cell projection organization 1 response to carbon monoxide 1 cell proliferation in forebrain 1 response to copper ion 1 cellular calcium ion homeostasis 1 response to corticosteroid 1 cellular chemical homeostasis 1 response to corticosterone 1 cellular chloride ion homeostasis 1 response to cortisol 1 cellular defense response 1 response to DDT 1 cellular heat acclimation 1 response to extracellular stimulus 1 cellular response to caffeine 1 response to folic acid 1 cellular response to cAMP 1 response to food 1 cellular response to cell-matrix adhesion 1 response to glucagon 1 cellular response to cytokine stimulus 1 response to growth hormone 1 cellular response to estradiol stimulus 1 response to herbicide 1 cellular response to ethanol 1 response to hydrostatic pressure 1 cellular response to extracellular stimulus 1 response to insecticide 1 cellular response to fibroblast growth factor stimulus 1 response to interferon-gamma 1 cellular response to fluid shear stress 1 response to magnetism 1 cellular response to freezing 1 response to manganese ion 1 cellular response to glucose stimulus 1 response to morphine 1 cellular response to granulocyte macrophage colony-stimulating factor stimulus 1 response to muramyl dipeptide 1 cellular response to growth factor stimulus 1 response to nicotine 1 cellular response to hormone stimulus 1 response to organophosphorus 1 cellular response to interferon-beta 1 response to osmotic stress 1 cellular response to interleukin-1 1 response to pH 1 cellular response to iron(III) ion 1 response to progesterone 1 cellular response to platelet-derived growth factor stimulus 1 response to selenium ion 1 cellular response to potassium ion 1 response to starvation 1 cellular response to superoxide 1 response to stimulus 1 cellular response to tumor necrosis factor 1 response to vitamin A 1 cellular response to vascular endothelial growth factor stimulus 1 retinoid metabolic process 1 central nervous system projection neuron axonogenesis 1 retrograde protein transport, ER to cytosol 1 centriolar satellite 1 ribonucleoside monophosphate biosynthetic process 1 centriole replication 1 ribose phosphate biosynthetic process 1 centrosomal corona 1 ribose phosphate metabolic process 1 centrosome organization 1 ribosomal protein import into nucleus 1 cerebellar cortex development 1 ribosomal small subunit assembly 1 cerebellar cortex structural organization 1 ripoptosome assembly involved in necroptotic process 1 cerebellar Purkinje cell differentiation 1 RNA catabolic process 1 cerebellar Purkinje cell layer development 1 RNA export from nucleus 1 cerebellar Purkinje cell layer morphogenesis 1 RNA import into nucleus 1 cerebral cortex development 1 RNA localization 1 chaperone-mediated protein transport 1 RNA secondary structure unwinding 1 chaperone cofactor-dependent protein refolding 1 RNA transport 1 chaperone mediated protein folding requiring cofactor 1 rostrocaudal neural tube patterning 1 chemokine production 1 rRNA catabolic process 1 chloride channel activity 1 ruffle organization 1 chloride channel complex 1 S-adenosylhomocysteine catabolic process 1 chloride transmembrane transport 1 sarcomerogenesis 1 chloride transport 1 SCF complex assembly 1 cholate 7-alpha-dehydrogenase activity 1 secretion 1 cholesterol biosynthetic process 1 secretory granule localization 1 choloyl-CoA hydrolase activity 1 selenocysteinyl-tRNA(Sec) biosynthetic process 1 chorismate metabolic process 1 sensory perception of smell 1 chromatin assembly 1 sensory perception of temperature stimulus 1 chromatin silencing 1 sequestering of calcium ion 1 chromatin silencing at rDNA 1 sequestering of zinc ion 1 chromatin silencing at telomere 1 serotonin metabolic process 1 chromatin silencing complex 1 sesquiterpenoid metabolic process 1 chromatoid body 1 signal transduction by phosphorylation 1 chromosome condensation 1 signal transduction involved in mitotic G1 DNA damage checkpoint 1 chromosome passenger complex localization to kinetochore 1 signal transduction involved in regulation of gene expression 1 chromosome separation 1 single fertilization 1 chromosome, centromeric core domain 1 single strand break repair 1 chronic inflammatory response 1 skeletal muscle cell differentiation 1 chronic inflammatory response to antigenic stimulus 1 skeletal muscle fiber adaptation 1 ciliary base 1 SMAD protein import into nucleus 1 circadian behavior 1 SMAD protein signal transduction 1 circadian regulation of translation 1 snoRNA metabolic process 1 circadian sleep/wake cycle 1 snRNA metabolic process 1 circadian sleep/wake cycle, non-REM sleep 1 snRNA modification 1 citrulline biosynthetic process 1 snRNA processing 1 clathrin coat assembly 1 sodium-independent organic anion transport 1 clathrin complex 1 sodium ion transmembrane transport 1 clathrin light chain binding 1 somatic diversification of immune receptors via somatic mutation 1 cleavage furrow formation 1 somatic recombination of immunoglobulin genes involved in immune response 1 cochlea development 1 somatic stem cell maintenance 1 coenzyme A metabolic process 1 sperm chromatin condensation 1 coenzyme binding 1 spinal cord motor neuron differentiation 1 cofactor binding 1 stem cell differentiation 1 cohesin complex 1 steroid biosynthetic process 1 collagen biosynthetic process 1 sterol regulatory element binding protein import into nucleus 1 collagen catabolic process 1 stress fiber assembly 1 collagen metabolic process 1 striated muscle cell development 1 collagen trimer 1 striated muscle cell differentiation 1 collagen type IV trimer 1 striatum development 1 common-partner SMAD protein phosphorylation 1 succinate metabolic process 1 condensed chromosome kinetochore 1 sulfur amino acid metabolic process 1 condensed chromosome outer kinetochore 1 superoxide anion generation 1 condensed chromosome, centromeric region 1 synapse assembly 1 contractile ring 1 synaptic vesicle exocytosis 1 convergent extension involved in axis elongation 1 synaptic vesicle targeting 1 cornification 1 synaptonemal complex disassembly 1 coronary artery morphogenesis 1 T cell chemotaxis 1 corpus callosum development 1 T cell costimulation 1 cortical actin cytoskeleton organization 1 T cell proliferation involved in immune response 1 cortical microtubule cytoskeleton 1 T cell receptor V(D)J recombination 1 creatine kinase activity 1 tangential migration from the subventricular zone to the olfactory bulb 1 creatine metabolic process 1 targeting of mRNA for destruction involved in RNA interference 1 cristae formation 1 termination of G-protein coupled receptor signaling pathway 1 CTP binding 1 tetrahydrobiopterin biosynthetic process 1 Cul5-RING ubiquitin ligase complex 1 tetrahydrofolate metabolic process 1 Cul7-RING ubiquitin ligase complex 1 thalamus development 1 CXCR chemokine receptor binding 1 third ventricle development 1 cyclic nucleotide binding 1 thymus development 1 cyclic nucleotide catabolic process 1 tissue homeostasis 1 cyclin-dependent protein kinase activating kinase holoenzyme complex 1 tolerance induction to lipopolysaccharide 1 cyclin catabolic process 1 tongue morphogenesis 1 cysteine-type endopeptidase activator activity involved in apoptotic process 1 TOR signaling 1 cytokine production involved in inflammatory response 1 transcription, RNA-templated 1 cytoplasmic side of endoplasmic reticulum membrane 1 transcriptional activation by promoter-enhancer looping 1 cytoplasmic translational initiation 1 transferrin transport 1 cytosine metabolic process 1 transition between slow and fast fiber 1 cytosolic calcium ion homeostasis 1 translocation of peptides or proteins into host cell cytoplasm 1 cytosolic ribosome 1 transmembrane receptor protein tyrosine phosphatase signaling pathway 1 D-gluconate metabolic process 1 triglyceride metabolic process 1 dATP binding 1 tRNA 5'-leader removal 1 dATP catabolic process 1 tRNA catabolic process 1 deadenylation-dependent decapping of nuclear-transcribed mRNA 1 tRNA methylation 1 death 1 tRNA modification 1 death receptor binding 1 trophectodermal cellular morphogenesis 1 decidualization 1 tryptophan transport 1 defense response 1 tubulin complex assembly 1 defense response to bacterium 1 type I interferon production 1 defense response to fungus 1 ubiquinone biosynthetic process 1 definitive hemopoiesis 1 ubiquitin-dependent SMAD protein catabolic process 1 delta-catenin binding 1 UDP-glucosylation 1 delta DNA polymerase complex 1 urea cycle 1 dendrite morphogenesis 1 ureteric bud development 1 dendritic cell chemotaxis 1 uropod organization 1 dendritic cell proliferation 1 UV protection 1 dendritic shaft 1 vagus nerve development 1 dendritic spine maintenance 1 valine catabolic process 1 dense core granule 1 valyl-tRNA aminoacylation 1 deoxyribonuclease activity 1 vasodilation 1 depurination 1 very-low-density lipoprotein particle assembly 1 detection of calcium ion 1 very long-chain fatty-acyl-CoA metabolic process 1 detection of mechanical stimulus 1 very long-chain fatty acid catabolic process 1 detection of muscle stretch 1 very long-chain fatty acid metabolic process 1 detection of UV 1 visual behavior 1 deubiquitinase activator activity 1 vitamin B6 metabolic process 1 developmental maturation 1 vocalization behavior 1 dGTP binding 1 water transport 1 dGTP catabolic process 1 zonula adherens maintenance 1 dGTPase activity 1 diadenosine tetraphosphate biosynthetic process 1 dicarboxylic acid catabolic process 1 dicarboxylic acid transport 1 digestive tract development 1 dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity 1 dinucleotide insertion or deletion binding 1 dinucleotide repeat insertion binding 1 dioxygenase activity 1 disulfide oxidoreductase activity 1 DNA-3-methyladenine glycosylase activity 1 DNA-3-methylguanine glycosylase activity 1 DNA-7-methyladenine glycosylase activity 1 DNA-7-methylguanine glycosylase activity 1 DNA-dependent protein kinase-DNA ligase 4 complex 1 DNA-methyltransferase activity 1 DNA binding, bending 1 DNA catabolic process, endonucleolytic 1 DNA clamp loader activity 1 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator 1 DNA double-strand break processing 1 DNA ligation 1 DNA methylation involved in embryo development 1 DNA methylation involved in gamete generation 1 DNA polymerase binding 1 DNA polymerase III complex 1 DNA replication checkpoint 1 DNA replication, removal of RNA primer 1 DNA rewinding 1 DNA translocase activity 1 dolichol-linked oligosaccharide biosynthetic process 1 dorsal/ventral neural tube patterning 1 double-strand/single-strand DNA junction binding 1 double-stranded DNA-dependent ATPase activity 1 dynein binding 1 dynein complex binding 1 dynein light intermediate chain binding 1 dystroglycan binding 1 early endosome to late endosome transport 1 eating behavior 1 ectopic germ cell programmed cell death 1 ectoplasm 1 elastic fiber assembly 1 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity 1 embryo development ending in birth or egg hatching 1 embryonic forelimb morphogenesis 1 embryonic hemopoiesis 1 embryonic hindlimb morphogenesis 1 embryonic placenta morphogenesis 1 embryonic skeletal system morphogenesis 1 endochondral bone morphogenesis 1 endoderm development 1 endoderm formation 1 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1 endoplasmic reticulum exit site 1 endoplasmic reticulum membrane fusion 1 endosomal vesicle fusion 1 endosome localization 1 endosome to lysosome transport 1 endothelial cell-cell adhesion 1 endothelial cell morphogenesis 1 endothelial tube morphogenesis 1 enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity 1 enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity 1 entrainment of circadian clock 1 entrainment of circadian clock by photoperiod 1 enzyme-directed rRNA 2'-O-methylation 1 epidermis morphogenesis 1 epithelial cell maturation 1 epithelial cell maturation involved in prostate gland development 1 epithelial cell migration 1 ER-mitochondrion membrane contact site 1 ER overload response 1 ERBB signaling pathway 1 erythrocyte maturation 1 establishment of apical/basal cell polarity 1 establishment of blood-nerve barrier 1 establishment of cell polarity 1 establishment of cell polarity involved in ameboidal cell migration 1 establishment of chromatin silencing 1 establishment of glial blood-brain barrier 1 establishment of meiotic spindle localization 1 establishment of neuroblast polarity 1 establishment of nucleus localization 1 establishment of planar polarity 1 establishment of protein localization to chromatin 1 establishment of protein localization to plasma membrane 1 establishment of protein localization to vacuole 1 establishment of spindle orientation 1 establishment of T cell polarity 1 establishment or maintenance of epithelial cell apical/basal polarity 1 estrogen metabolic process 1 estrous cycle phase 1 euchromatin 1 eukaryotic initiation factor 4G binding 1 eukaryotic translation elongation factor 1 complex 1 eukaryotic translation initiation factor 2alpha kinase activity 1 eukaryotic translation initiation factor 2B complex 1 exocyst 1 exonuclease activity 1 exoribonuclease activity 1 exosomal secretion 1 extracellular amino acid transport 1 extracellular matrix structural constituent 1 extrinsic apoptotic signaling pathway in absence of ligand 1 extrinsic apoptotic signaling pathway via death domain receptors 1 extrinsic component of plasma membrane 1 eye pigmentation 1 F-actin capping protein complex 1 face morphogenesis 1 FAD binding 1 fat cell differentiation 1 fatty acid binding 1 Fc-gamma receptor I complex binding 1 female gamete generation 1 female meiosis I 1 ferrous iron binding 1 fibrillar center 1 fibroblast migration 1 fibronectin binding 1 filamentous actin 1 filopodium assembly 1 focal adhesion assembly 1 folic acid-containing compound metabolic process 1 folic acid metabolic process 1 forebrain morphogenesis 1 formate metabolic process 1 forward locomotion 1 fourth ventricle development 1 frizzled binding 1 fructose 1,6-bisphosphate metabolic process 1 fructose 6-phosphate metabolic process 1 fructose binding 1 fucose binding 1 fucosidase activity 1 G-protein alpha-subunit binding 1 G-protein beta-subunit binding 1 G-protein coupled acetylcholine receptor signaling pathway 1 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger 1 GABA receptor binding 1 GAF domain binding 1 galactitol metabolic process 1 galactose binding 1 galactose catabolic process 1 galactoside binding 1 gamma-catenin-TCF7L2 complex 1 gap junction assembly 1 gastrulation with mouth forming second 1 GDP-mannose biosynthetic process 1 GDP binding 1 gene silencing 1 germ cell development 1 gliogenesis 1 glomerular visceral epithelial cell development 1 glossopharyngeal nerve development 1 glucan 1,3-alpha-glucosidase activity 1 glucocorticoid catabolic process 1 glucocorticoid receptor binding 1 glucose homeostasis 1 glucosidase II complex 1 glutamate metabolic process 1 glutamine catabolic process 1 glutamine transport 1 glutaminyl-peptide cyclotransferase activity 1 glutamyl-tRNA aminoacylation 1 glutathione biosynthetic process 1 glutathione hydrolase activity 1 glycerol ether metabolic process 1 glycine betaine biosynthetic process from choline 1 glycine biosynthetic process 1 glycine biosynthetic process from serine 1 glycine catabolic process 1 glycine dehydrogenase (decarboxylating) activity 1 glycogen granule 1 glycolipid binding 1 glycosaminoglycan catabolic process 1 glycosphingolipid catabolic process 1 glycyl-tRNA aminoacylation 1 GMP synthase (glutamine-hydrolyzing) activity 1 Golgi cisterna 1 Golgi reassembly 1 Golgi ribbon formation 1 Golgi to endosome transport 1 Golgi to lysosome transport 1 Golgi to plasma membrane CFTR protein transport 1 granular component 1 Grb2-EGFR complex 1 GTP biosynthetic process 1 GTPase binding 1 guanyl nucleotide binding 1 hair follicle development 1 hair follicle morphogenesis 1 head development 1 head morphogenesis 1 heart growth 1 heart morphogenesis 1 hematopoietic stem cell differentiation 1 hematopoietic stem cell homeostasis 1 hematopoietic stem cell proliferation 1 hemidesmosome 1 hemoglobin metabolic process 1 hemolysis by symbiont of host erythrocytes 1 hemopoiesis 1 hepatocyte differentiation 1 heteroduplex DNA loop binding 1 heterotrimeric G-protein binding 1 heterotrimeric G-protein complex 1 high-density lipoprotein particle 1 histamine secretion by mast cell 1 histidine ammonia-lyase activity 1 histidine biosynthetic process 1 histidine catabolic process to glutamate and formamide 1 histidine catabolic process to glutamate and formate 1 histone-arginine N-methyltransferase activity 1 histone-glutamine methyltransferase activity 1 histone acetyltransferase activity (H4-K12 specific) 1 histone acetyltransferase binding 1 histone arginine methylation 1 histone deacetylase activity 1 histone deacetylase complex 1 histone deacetylase regulator activity 1 histone demethylase activity (H3-R2 specific) 1 histone demethylase activity (H4-R3 specific) 1 histone glutamine methylation 1 histone H2A-T120 phosphorylation 1 histone H2B conserved C-terminal lysine deubiquitination 1 histone H3-K14 acetylation 1 histone H3-K4 trimethylation 1 histone H3-R2 demethylation 1 histone H3-R2 methylation 1 histone H3-S10 phosphorylation involved in chromosome condensation 1 histone H3-T11 phosphorylation 1 histone H4-K12 acetylation 1 histone H4-R3 demethylation 1 histone kinase activity 1 histone kinase activity (H2A-T120 specific) 1 histone methyltransferase binding 1 histone mRNA metabolic process 1 histone phosphorylation 1 HLH domain binding 1 homocysteine biosynthetic process 1 hormone activity 1 Hrd1p ubiquitin ligase complex 1 hydrolase activity, acting on acid anhydrides 1 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides 1 hydroxylysine biosynthetic process 1 I-kappaB kinase/NF-kappaB signaling 1 IgG binding 1 immunoglobulin V(D)J recombination 1 IMP dehydrogenase activity 1 importin-alpha export receptor activity 1 inner cell mass cell proliferation 1 inner ear morphogenesis 1 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity 1 inositol phosphate-mediated signaling 1 inositol phosphate metabolic process 1 insulin-like growth factor-activated receptor activity 1 insulin-like growth factor binding 1 insulin-like growth factor II binding 1 insulin-like growth factor receptor signaling pathway 1 insulin receptor binding 1 integral component of lumenal side of endoplasmic reticulum membrane 1 integrin complex 1 interferon-gamma binding 1 interkinetic nuclear migration 1 interleukin-1 binding 1 interleukin-2 receptor binding 1 intermediate filament-based process 1 intermediate filament binding 1 interstitial matrix 1 intraciliary retrograde transport 1 ion channel activity 1 ionotropic glutamate receptor binding 1 IRES-dependent translational initiation 1 iron-responsive element binding 1 iron ion homeostasis 1 isoamylase complex 1 isoleucyl-tRNA aminoacylation 1 isotype switching to IgG isotypes 1 JAK-STAT cascade 1 JAK-STAT cascade involved in growth hormone signaling pathway 1 JNK cascade 1 keratinocyte activation 1 keratinocyte migration 1 keratinocyte proliferation 1 kinase regulator activity 1 kinesin binding 1 Krueppel-associated box domain binding 1 L-alanine catabolic process 1 L-alanine metabolic process 1 L-alanine:2-oxoglutarate aminotransferase activity 1 L-allo-threonine aldolase activity 1 L-aminoadipate-semialdehyde dehydrogenase activity 1 L-aspartate transmembrane transporter activity 1 L-glutamate transport 1 L-glutamine transmembrane transporter activity 1 L-phenylalanine catabolic process 1 L-serine biosynthetic process 1 L-serine metabolic process 1 L-serine transmembrane transporter activity 1 L-serine transport 1 labyrinthine layer blood vessel development 1 lactate dehydrogenase activity 1 lactate metabolic process 1 lactation 1 lamellipodium assembly 1 lamellipodium membrane 1 laminin binding 1 large ribosomal subunit 1 late endosome to Golgi transport 1 lateral element 1 lens development in camera-type eye 1 lens fiber cell development 1 leucine catabolic process 1 leukocyte chemotaxis 1 leukocyte migration involved in inflammatory response 1 leukotriene biosynthetic process 1 ligand-dependent nuclear receptor binding 1 limb morphogenesis 1 lipase binding 1 lipase inhibitor activity 1 lipid biosynthetic process 1 lipid homeostasis 1 lipid particle organization 1 lipid transporter activity 1 lipid tube assembly 1 lipopolysaccharide biosynthetic process 1 lipopolysaccharide receptor complex 1 lipoprotein particle receptor binding 1 lipoprotein transport 1 lipoprotein transporter activity 1 lipoxygenase pathway 1 lithium ion binding 1 long-chain-alcohol oxidase activity 1 long-chain-aldehyde dehydrogenase activity 1 long-chain fatty acid biosynthetic process 1 long-term memory 1 low-density lipoprotein particle 1 low-density lipoprotein particle binding 1 lung lobe morphogenesis 1 lymphocyte differentiation 1 lymphocyte proliferation 1 macrophage activation 1 macrophage differentiation 1 macropinosome 1 maintenance of chromatin silencing 1 maintenance of DNA repeat elements 1 maintenance of mitochondrion location 1 male germ cell proliferation 1 male pronucleus 1 malonyl-CoA biosynthetic process 1 mammary gland epithelial cell proliferation 1 mammary gland involution 1 manganese ion binding 1 mannose-1-phosphate guanylyltransferase activity 1 mast cell degranulation 1 maturation of 5.8S rRNA 1 medium-chain-aldehyde dehydrogenase activity 1 medium-chain acyl-CoA hydrolase activity 1 medium-chain fatty-acyl-CoA metabolic process 1 medium-chain fatty acid catabolic process 1 meiosis I 1 meiotic gene conversion 1 meiotic spindle organization 1 melanocyte differentiation 1 membrane-bounded vesicle 1 membrane assembly 1 membrane depolarization during action potential 1 membrane depolarization during cardiac muscle cell action potential 1 membrane hyperpolarization 1 membrane invagination 1 membrane repolarization 1 mesoderm development 1 metalloaminopeptidase activity 1 metalloendopeptidase activity 1 metaphase/anaphase transition of mitotic cell cycle 1 metencephalon development 1 methenyltetrahydrofolate cyclohydrolase activity 1 methionine biosynthetic process 1 methionyl-tRNA aminoacylation 1 methyl-CpG binding 1 methylation-dependent chromatin silencing 1 methylcrotonoyl-CoA carboxylase activity 1 methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity 1 MHC class I protein complex 1 MHC class II protein binding 1 MHC class II receptor activity 1 microtubule bundle 1 microtubule depolymerization 1 microtubule nucleation 1 middle ear morphogenesis 1 miRNA metabolic process 1 misfolded protein binding 1 mitochondrial alpha-ketoglutarate dehydrogenase complex 1 mitochondrial calcium ion homeostasis 1 mitochondrial DNA metabolic process 1 mitochondrial DNA repair 1 mitochondrial electron transport, NADH to ubiquinone 1 mitochondrial fragmentation involved in apoptotic process 1 mitochondrial genome maintenance 1 mitochondrial heavy strand promoter anti-sense binding 1 mitochondrial light strand promoter sense binding 1 mitochondrial membrane organization 1 mitochondrial protein processing 1 mitochondrial proton-transporting ATP synthase, catalytic core 1 mitochondrial pyruvate dehydrogenase complex 1 mitochondrial respiratory chain complex assembly 1 mitochondrial respiratory chain complex I 1 mitochondrial respiratory chain complex I assembly 1 mitochondrial RNA 5'-end processing 1 mitochondrial translation 1 mitochondrial transport 1 mitochondrion localization 1 mitochondrion transport along microtubule 1 mitogen-activated protein kinase kinase binding 1 mitogen-activated protein kinase kinase kinase binding 1 mitotic cell cycle arrest 1 mitotic centrosome separation 1 mitotic spindle stabilization 1 modulation by virus of host morphology or physiology 1 monocyte differentiation 1 monosaccharide binding 1 monovalent inorganic cation transmembrane transporter activity 1 monovalent inorganic cation transport 1 motile cilium assembly 1 motile primary cilium 1 motor neuron axon guidance 1 mRNA 3'-UTR AU-rich region binding 1 mRNA 5'-UTR binding 1 mRNA cis splicing, via spliceosome 1 mRNA export from nucleus in response to heat stress 1 mRNA modification 1 mRNA transcription from RNA polymerase II promoter 1 mu-type opioid receptor binding 1 multicellular organismal iron ion homeostasis 1 multicellular organismal protein metabolic process 1 multivesicular body 1 multivesicular body sorting pathway 1 muscle alpha-actinin binding 1 muscle thin filament tropomyosin 1 Myb complex 1 myelin sheath adaxonal region 1 myoblast fusion 1 myofibril assembly 1 myosin VI light chain binding 1 myotube cell development 1 myristoyl-[acyl-carrier-protein] hydrolase activity 1 N-acetylmannosamine metabolic process 1 N-acylglucosamine-6-phosphate 2-epimerase activity 1 N-terminal myristoylation domain binding 1 N-terminal protein amino acid acetylation 1 N-terminal protein amino acid modification 1 NAD metabolic process 1 NAD+ binding 1 NADH metabolic process 1 NADP metabolic process 1 NADPH binding 1 NADPH regeneration 1 nail development 1 NatA complex 1 natural killer cell chemotaxis 1 ncRNA metabolic process 1 negative regulation of adenylate cyclase activity 1 negative regulation of alpha-beta T cell proliferation 1 negative regulation of androgen receptor signaling pathway 1 negative regulation of autophagy 1 negative regulation of blood vessel endothelial cell migration 1 negative regulation of BMP signaling pathway 1 negative regulation of bone resorption 1 negative regulation of cardiac muscle contraction 1 negative regulation of CD40 signaling pathway 1 negative regulation of cell-cell adhesion 1 negative regulation of cell adhesion involved in substrate-bound cell migration 1 negative regulation of cell cycle arrest 1 negative regulation of cell motility 1 negative regulation of cell proliferation involved in contact inhibition 1 negative regulation of cellular component movement 1 negative regulation of cellular response to testosterone stimulus 1 negative regulation of cellular senescence 1 negative regulation of centrosome duplication 1 negative regulation of cholesterol biosynthetic process 1 negative regulation of chromatin binding 1 negative regulation of chronic inflammatory response 1 negative regulation of collagen binding 1 negative regulation of cyclic-nucleotide phosphodiesterase activity 1 negative regulation of defense response to virus by host 1 negative regulation of dephosphorylation 1 negative regulation of DNA biosynthetic process 1 negative regulation of DNA demethylation 1 negative regulation of endothelial cell apoptotic process 1 negative regulation of endothelial cell proliferation 1 negative regulation of epithelial to mesenchymal transition 1 negative regulation of establishment of protein localization to plasma membrane 1 negative regulation of estrogen receptor binding 1 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand 1 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors 1 negative regulation of fatty acid biosynthetic process 1 negative regulation of fibroblast apoptotic process 1 negative regulation of G-protein coupled receptor protein signaling pathway 1 negative regulation of G1/S transition of mitotic cell cycle 1 negative regulation of G2/M transition of mitotic cell cycle 1 negative regulation of glucocorticoid biosynthetic process 1 negative regulation of glucokinase activity 1 negative regulation of granulocyte differentiation 1 negative regulation of heart induction by canonical Wnt signaling pathway 1 negative regulation of histone acetylation 1 negative regulation of histone deacetylation 1 negative regulation of histone H3-K9 methylation 1 negative regulation of hyaluronan biosynthetic process 1 negative regulation of inclusion body assembly 1 negative regulation of insulin secretion 1 negative regulation of insulin secretion involved in cellular response to glucose stimulus 1 negative regulation of integrin-mediated signaling pathway 1 negative regulation of interleukin-1 beta production 1 negative regulation of interleukin-2 production 1 negative regulation of interleukin-8 production 1 negative regulation of interleukin-8 secretion 1 negative regulation of intrinsic apoptotic signaling pathway 1 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator 1 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage 1 negative regulation of ion transmembrane transport 1 negative regulation of JAK-STAT cascade 1 negative regulation of JUN kinase activity 1 negative regulation of lymphocyte differentiation 1 negative regulation of macromitophagy 1 negative regulation of MAPK cascade 1 negative regulation of microtubule depolymerization 1 negative regulation of microtubule polymerization 1 negative regulation of microtubule polymerization or depolymerization 1 negative regulation of mitochondrial RNA catabolic process 1 negative regulation of mitosis 1 negative regulation of mitotic anaphase-promoting complex activity 1 negative regulation of multicellular organism growth 1 negative regulation of muscle cell differentiation 1 negative regulation of neuron differentiation 1 negative regulation of neuron projection regeneration 1 negative regulation of Notch signaling pathway 1 negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway 1 negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway 1 negative regulation of osteoclast proliferation 1 negative regulation of peptidyl-lysine acetylation 1 negative regulation of peptidyl-serine dephosphorylation 1 negative regulation of peptidyl-threonine phosphorylation 1 negative regulation of phagocytosis 1 negative regulation of phospholipase A2 activity 1 negative regulation of post-translational protein modification 1 negative regulation of protein deubiquitination 1 negative regulation of protein glutathionylation 1 negative regulation of protein homooligomerization 1 negative regulation of protein localization to nucleus 1 negative regulation of protein localization to plasma membrane 1 negative regulation of protein oligomerization 1 negative regulation of protein polymerization 1 negative regulation of protein processing 1 negative regulation of protein secretion 1 negative regulation of protein targeting to membrane 1 negative regulation of protein tyrosine kinase activity 1 negative regulation of proteolysis 1 negative regulation of Ras GTPase activity 1 negative regulation of Ras protein signal transduction 1 negative regulation of reactive oxygen species metabolic process 1 negative regulation of receptor binding 1 negative regulation of receptor internalization 1 negative regulation of reciprocal meiotic recombination 1 negative regulation of Rho-dependent protein serine/threonine kinase activity 1 negative regulation of Rho protein signal transduction 1 negative regulation of RNA interference 1 negative regulation of RNA splicing 1 negative regulation of ryanodine-sensitive calcium-release channel activity 1 negative regulation of smooth muscle cell differentiation 1 negative regulation of smooth muscle cell proliferation 1 negative regulation of smoothened signaling pathway 1 negative regulation of stress-activated MAPK cascade 1 negative regulation of striated muscle contraction 1 negative regulation of striated muscle tissue development 1 negative regulation of synaptic transmission 1 negative regulation of T cell apoptotic process 1 negative regulation of T cell differentiation 1 negative regulation of telomere maintenance 1 negative regulation of toll-like receptor 2 signaling pathway 1 negative regulation of toll-like receptor 3 signaling pathway 1 negative regulation of toll-like receptor 4 signaling pathway 1 negative regulation of toll-like receptor 5 signaling pathway 1 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia 1 negative regulation of translation in response to stress 1 negative regulation of translational elongation 1 negative regulation of transmembrane transport 1 negative regulation of transporter activity 1 negative regulation of triglyceride catabolic process 1 negative regulation of type I interferon-mediated signaling pathway 1 negative regulation of viral transcription 1 negative regulation of Wnt signaling pathway involved in heart development 1 nerve development 1 neural tube patterning 1 neuroendocrine cell differentiation 1 neuron projection morphogenesis 1 neuron projection terminus 1 neuronal action potential 1 neurotransmitter receptor metabolic process 1 neurotransmitter uptake 1 neurotrophin TRKA receptor binding 1 neutrophil aggregation 1 neutrophil clearance 1 neutrophil extravasation 1 NF-kappaB-inducing kinase activity 1 NIK/NF-kappaB signaling 1 nitrogen compound metabolic process 1 nitrogen cycle metabolic process 1 nitronate monooxygenase activity 1 nonmotile primary cilium 1 nose development 1 Notch binding 1 nuclear cap binding complex 1 nuclear cyclin-dependent protein kinase holoenzyme complex 1 nuclear lamina 1 nuclear localization sequence binding 1 nuclear lumen 1 nuclear meiotic cohesin complex 1 nuclear mRNA surveillance 1 nuclear origin of replication recognition complex 1 nuclear outer membrane 1 nuclear outer membrane-endoplasmic reticulum membrane network 1 nuclear pericentric heterochromatin 1 nuclear polyadenylation-dependent rRNA catabolic process 1 nuclear proteasome complex 1 nuclear retention of unspliced pre-mRNA at the site of transcription 1 nucleologenesis 1 nucleoside-triphosphatase activity 1 nucleoside binding 1 nucleoside diphosphate phosphorylation 1 nucleosomal DNA binding 1 nucleosome binding 1 nucleosome mobilization 1 nucleosome positioning 1 nucleotide-excision repair, DNA damage recognition 1 nucleotide phosphatase activity, acting on free nucleotides 1 nucleus localization 1 oleoyl-[acyl-carrier-protein] hydrolase activity 1 olfactory bulb development 1 olfactory bulb mitral cell layer development 1 olfactory nerve structural organization 1 oligodendrocyte apoptotic process 1 oligodendrocyte development 1 oligodendrocyte differentiation 1 oligosaccharide metabolic process 1 oligosaccharyltransferase complex 1 oocyte development 1 optic cup formation involved in camera-type eye development 1 optic nerve development 1 organic acid metabolic process 1 ornithine-oxo-acid transaminase activity 1 ornithine biosynthetic process 1 outer ear morphogenesis 1 outflow tract morphogenesis 1 ovulation from ovarian follicle 1 oxidative phosphorylation 1 oxidative RNA demethylase activity 1 oxidative single-stranded RNA demethylation 1 oxidative stress-induced premature senescence 1 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor 1 oxoglutarate dehydrogenase (NAD+) activity 1 oxoglutarate dehydrogenase complex 1 oxygen binding 1 oxygen sensor activity 1 palmitoyl-[acyl-carrier-protein] hydrolase activity 1 palmitoyl-CoA hydrolase activity 1 pancreatic juice secretion 1 pantothenate metabolic process 1 paraxial mesoderm development 1 Parkin-FBXW7-Cul1 ubiquitin ligase complex 1 patched binding 1 pathogenesis 1 pathway-restricted SMAD protein phosphorylation 1 PCAF complex 1 PeBoW complex 1 pentose-phosphate shunt, non-oxidative branch 1 peptide alpha-N-acetyltransferase activity 1 peptide antigen binding 1 peptidyl-asparagine 3-dioxygenase activity 1 peptidyl-asparagine hydroxylation 1 peptidyl-aspartic acid hydroxylation 1 peptidyl-histidine dioxygenase activity 1 peptidyl-histidine hydroxylation 1 peptidyl-lysine 5-dioxygenase activity 1 peptidyl-lysine acetylation 1 peptidyl-lysine deacetylation 1 peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine 1 peptidyl-methionine modification 1 peptidyl-proline hydroxylation 1 peptidyl-proline hydroxylation to 4-hydroxy-L-proline 1 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase 1 peptidyl-serine dephosphorylation 1 peptidyl-threonine dephosphorylation 1 peptidyl-tyrosine phosphorylation 1 pericardium development 1 pericentric heterochromatin 1 peripheral nervous system development 1 peroxisome fission 1 peroxisome organization 1 peroxisome targeting sequence binding 1 phagocytic cup 1 phagocytic vesicle 1 phagocytosis 1 phagolysosome assembly 1 phenylalanine 4-monooxygenase activity 1 phosphate ion carrier activity 1 phosphate ion transmembrane transport 1 phosphatidic acid binding 1 phosphatidylinositol-3-phosphate binding 1 phosphatidylinositol-3-phosphate biosynthetic process 1 phosphatidylinositol-4-phosphate binding 1 phosphatidylinositol-4,5-bisphosphate 3-kinase activity 1 phosphatidylinositol-5-phosphate binding 1 phosphatidylinositol 3-kinase activity 1 phosphatidylinositol 3-kinase complex 1 phosphatidylinositol 3-kinase complex, class IB 1 phosphatidylinositol 3-kinase signaling 1 phosphatidylinositol biosynthetic process 1 phosphatidylinositol phosphate binding 1 phosphatidylinositol phosphorylation 1 phosphatidylserine binding 1 phospholipase inhibitor activity 1 phospholipid-hydroperoxide glutathione peroxidase activity 1 phosphopantetheine binding 1 phosphoribosylaminoimidazole carboxylase activity 1 phosphorylase activity 1 photoreceptor cell maintenance 1 photoreceptor cell outer segment organization 1 photoreceptor outer segment membrane 1 phytol metabolic process 1 placenta blood vessel development 1 plasma membrane repair 1 platelet-derived growth factor receptor signaling pathway 1 platelet dense tubular network membrane 1 platelet formation 1 plus-end-directed vesicle transport along microtubule 1 podosome 1 pointed-end actin filament capping 1 polar body extrusion after meiotic divisions 1 poly-pyrimidine tract binding 1 poly(A) binding 1 polynucleotide adenylyltransferase activity 1 polysaccharide binding 1 polysomal ribosome 1 pore complex 1 porin activity 1 porphyrin-containing compound biosynthetic process 1 porphyrin-containing compound metabolic process 1 positive regulation by host of viral genome replication 1 positive regulation of abscisic acid-activated signaling pathway 1 positive regulation of actin cytoskeleton reorganization 1 positive regulation of actin filament polymerization 1 positive regulation of activin receptor signaling pathway 1 positive regulation of acute inflammatory response 1 positive regulation of adaptive immune response 1 positive regulation of astrocyte differentiation 1 positive regulation of autophagy 1 positive regulation of bone mineralization involved in bone maturation 1 positive regulation of bone resorption 1 positive regulation of cAMP catabolic process 1 positive regulation of cardiac muscle cell apoptotic process 1 positive regulation of cardiac muscle cell proliferation 1 positive regulation of catenin import into nucleus 1 positive regulation of cell cycle process 1 positive regulation of cell death 1 positive regulation of cell division 1 positive regulation of cellular pH reduction 1 positive regulation of cellular protein catabolic process 1 positive regulation of cellular senescence 1 positive regulation of chaperone-mediated protein complex assembly 1 positive regulation of cholesterol homeostasis 1 positive regulation of chromatin silencing 1 positive regulation of circadian sleep/wake cycle, non-REM sleep 1 positive regulation of cyclic nucleotide metabolic process 1 positive regulation of cyclin-dependent protein serine/threonine kinase activity 1 positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle 1 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process 1 positive regulation of cytokine production 1 positive regulation of cytoplasmic mRNA processing body assembly 1 positive regulation of cytosolic calcium ion concentration 1 positive regulation of cytotoxic T cell differentiation 1 positive regulation of dephosphorylation 1 positive regulation of DNA-templated transcription, initiation 1 positive regulation of DNA binding 1 positive regulation of DNA damage checkpoint 1 positive regulation of DNA replication 1 positive regulation of early endosome to recycling endosome transport 1 positive regulation of embryonic development 1 positive regulation of endocytic recycling 1 positive regulation of endothelial cell chemotaxis 1 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway 1 positive regulation of endothelial cell proliferation 1 positive regulation of ER to Golgi vesicle-mediated transport 1 positive regulation of establishment of protein localization to plasma membrane 1 positive regulation of exocytosis 1 positive regulation of extrinsic apoptotic signaling pathway 1 positive regulation of gastrulation 1 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter 1 positive regulation of glucose import 1 positive regulation of hair follicle development 1 positive regulation of heart contraction 1 positive regulation of hepatocyte proliferation 1 positive regulation of heterochromatin assembly 1 positive regulation of histone acetylation 1 positive regulation of histone H3-K27 methylation 1 positive regulation of histone H3-K27 trimethylation 1 positive regulation of histone H3-K9 methylation 1 positive regulation of histone modification 1 positive regulation of histone phosphorylation 1 positive regulation of inflammatory response 1 positive regulation of insulin receptor signaling pathway 1 positive regulation of interferon-beta biosynthetic process 1 positive regulation of interleukin-10 production 1 positive regulation of interleukin-12 production 1 positive regulation of interleukin-6 production 1 positive regulation of intracellular estrogen receptor signaling pathway 1 positive regulation of JUN kinase activity 1 positive regulation of kinase activity 1 positive regulation of Lys63-specific deubiquitinase activity 1 positive regulation of macrophage activation 1 positive regulation of mammary gland epithelial cell proliferation 1 positive regulation of MAP kinase activity 1 positive regulation of MDA-5 signaling pathway 1 positive regulation of meiosis I 1 positive regulation of membrane protein ectodomain proteolysis 1 positive regulation of MHC class I biosynthetic process 1 positive regulation of MHC class II biosynthetic process 1 positive regulation of mitochondrial depolarization 1 positive regulation of mitochondrial membrane permeability 1 positive regulation of mitotic cell cycle phase transition 1 positive regulation of mitotic cell cycle spindle assembly checkpoint 1 positive regulation of mitotic metaphase/anaphase transition 1 positive regulation of monocyte differentiation 1 positive regulation of mRNA catabolic process 1 positive regulation of multicellular organism growth 1 positive regulation of myoblast differentiation 1 positive regulation of neuron differentiation 1 positive regulation of neutrophil apoptotic process 1 positive regulation of nitric-oxide synthase activity 1 positive regulation of NK T cell activation 1 positive regulation of peptide secretion 1 positive regulation of peroxisome proliferator activated receptor signaling pathway 1 positive regulation of phosphoprotein phosphatase activity 1 positive regulation of prostaglandin biosynthetic process 1 positive regulation of protein binding 1 positive regulation of protein dephosphorylation 1 positive regulation of protein exit from endoplasmic reticulum 1 positive regulation of protein homodimerization activity 1 positive regulation of protein homooligomerization 1 positive regulation of protein K63-linked deubiquitination 1 positive regulation of protein localization to early endosome 1 positive regulation of protein transport 1 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process 1 positive regulation of Rab GTPase activity 1 positive regulation of Rac protein signal transduction 1 positive regulation of receptor recycling 1 positive regulation of release of cytochrome c from mitochondria 1 positive regulation of Rho GTPase activity 1 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly 1 positive regulation of RNA splicing 1 positive regulation of ryanodine-sensitive calcium-release channel activity 1 positive regulation of skeletal muscle tissue development 1 positive regulation of SMAD protein import into nucleus 1 positive regulation of smooth muscle cell apoptotic process 1 positive regulation of smooth muscle cell proliferation 1 positive regulation of sodium ion transport 1 positive regulation of sodium:proton antiporter activity 1 positive regulation of stress fiber assembly 1 positive regulation of striated muscle contraction 1 positive regulation of superoxide anion generation 1 positive regulation of T cell anergy 1 positive regulation of T cell mediated cytotoxicity 1 positive regulation of T cell mediated immune response to tumor cell 1 positive regulation of transcription elongation from RNA polymerase II promoter 1 positive regulation of transcription regulatory region DNA binding 1 positive regulation of transforming growth factor beta1 production 1 positive regulation of translational elongation 1 positive regulation of vasculogenesis 1 positive regulation of vesicle fusion 1 positive regulation of viral entry into host cell 1 positive regulation of viral release from host cell 1 posttranslational protein targeting to membrane 1 potassium channel regulator activity 1 POZ domain binding 1 pre-mRNA binding 1 pre-mRNA intronic binding 1 pre-mRNA intronic pyrimidine-rich binding 1 prefoldin complex 1 presynaptic cytoskeletal matrix assembled at active zones 1 pro-B cell differentiation 1 procollagen-proline 3-dioxygenase activity 1 procollagen-proline 4-dioxygenase activity 1 procollagen-proline 4-dioxygenase complex 1 procollagen galactosyltransferase activity 1 production of miRNAs involved in gene silencing by miRNA 1 progesterone receptor signaling pathway 1 prolactin secretion 1 proline-rich region binding 1 prolyl-tRNA aminoacylation 1 prostate gland development 1 prostate gland morphogenesis 1 proteasomal ubiquitin-independent protein catabolic process 1 proteasome activator complex 1 proteasome regulatory particle assembly 1 proteasome regulatory particle, lid subcomplex 1 protection from non-homologous end joining at telomere 1 protein-DNA complex 1 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity 1 protein autoprocessing 1 protein desumoylation 1 protein deubiquitination involved in ubiquitin-dependent protein catabolic process 1 protein heterotetramerization 1 protein heterotrimerization 1 protein homotrimerization 1 protein hydroxylation 1 protein import into nucleus, translocation 1 protein initiator methionine removal 1 protein K27-linked deubiquitination 1 protein K29-linked ubiquitination 1 protein K33-linked ubiquitination 1 protein kinase A catalytic subunit binding 1 protein kinase A regulatory subunit binding 1 protein kinase activator activity 1 protein kinase C-activating G-protein coupled receptor signaling pathway 1 protein kinase C activity 1 protein kinase inhibitor activity 1 protein localization to chromatin 1 protein localization to chromosome, telomeric region 1 protein localization to endoplasmic reticulum 1 protein localization to Golgi apparatus 1 protein localization to membrane 1 protein localization to mitochondrion 1 protein localization to organelle 1 protein localization to synapse 1 protein localization to tight junction 1 protein maturation by protein folding 1 protein metabolic process 1 protein N-acetylglucosaminyltransferase activity 1 protein O-linked glycosylation 1 protein phosphatase 1 binding 1 protein phosphatase 2B binding 1 protein phosphatase 4 complex 1 protein phosphatase activator activity 1 protein phosphatase type 1 complex 1 protein secretion 1 protein serine/threonine/tyrosine kinase activity 1 protein targeting to ER 1 protein transmembrane transport 1 protein transmembrane transporter activity 1 protein trimerization 1 protein tyrosine kinase inhibitor activity 1 proton-transporting ATP synthase complex, catalytic core F(1) 1 pulmonary artery morphogenesis 1 purine nucleobase binding 1 purine nucleotide binding 1 purine nucleotide catabolic process 1 purine ribonucleoside triphosphate binding 1 pyramidal neuron development 1 pyridoxal 5'-phosphate salvage 1 pyridoxal phosphate biosynthetic process 1 pyrimidine dimer repair 1 pyrimidine nucleoside biosynthetic process 1 pyrimidine nucleoside metabolic process 1 pyrimidine nucleotide metabolic process 1 pyrophosphatase activity 1 pyrroline-5-carboxylate reductase activity 1 pyruvate biosynthetic process 1 pyruvate dehydrogenase complex 1 Rab GTPase activator activity 1 radial glia guided migration of Purkinje cell 1 raffinose alpha-galactosidase activity 1 RAGE receptor binding 1 Ral GTPase binding 1 Ras GTPase binding 1 rDNA heterochromatin 1 receptor-mediated virion attachment to host cell 1 receptor clustering 1 receptor signaling complex scaffold activity 1 receptor signaling protein activity 1 receptor signaling protein serine/threonine kinase activity 1 recognition of apoptotic cell 1 recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex 1 recycling endosome to Golgi transport 1 regulation of acetyl-CoA biosynthetic process from pyruvate 1 regulation of actin filament polymerization 1 regulation of apoptotic DNA fragmentation 1 regulation of ARF protein signal transduction 1 regulation of axon extension 1 regulation of BMP signaling pathway 1 regulation of calcium ion transport 1 regulation of cardiac muscle contraction 1 regulation of cargo loading into COPII-coated vesicle 1 regulation of cell-substrate adhesion 1 regulation of cell adhesion mediated by integrin 1 regulation of cell communication by electrical coupling involved in cardiac conduction 1 regulation of cell death 1 regulation of cell division 1 regulation of cell growth by extracellular stimulus 1 regulation of cell motility 1 regulation of cellular response to growth factor stimulus 1 regulation of cellular response to hypoxia 1 regulation of centriole replication 1 regulation of centrosome duplication 1 regulation of chemotaxis 1 regulation of chloride transport 1 regulation of chromosome condensation 1 regulation of cysteine-type endopeptidase activity involved in apoptotic process 1 regulation of cytokine production 1 regulation of definitive erythrocyte differentiation 1 regulation of dendritic spine morphogenesis 1 regulation of DNA-dependent DNA replication initiation 1 regulation of DNA-templated transcription in response to stress 1 regulation of DNA-templated transcription, initiation 1 regulation of DNA binding 1 regulation of early endosome to late endosome transport 1 regulation of eIF2 alpha phosphorylation by dsRNA 1 regulation of eIF2 alpha phosphorylation by heme 1 regulation of endoribonuclease activity 1 regulation of epidermal cell differentiation 1 regulation of epithelial cell proliferation 1 regulation of establishment of cell polarity 1 regulation of establishment of planar polarity involved in neural tube closure 1 regulation of establishment of protein localization to plasma membrane 1 regulation of exit from mitosis 1 regulation of exocytosis 1 regulation of extrinsic apoptotic signaling pathway via death domain receptors 1 regulation of fatty acid beta-oxidation 1 regulation of fibroblast apoptotic process 1 regulation of gene silencing by miRNA 1 regulation of genetic imprinting 1 regulation of glucocorticoid metabolic process 1 regulation of gluconeogenesis 1 regulation of glycolytic process 1 regulation of Golgi inheritance 1 regulation of growth plate cartilage chondrocyte proliferation 1 regulation of growth rate 1 regulation of heart rate by hormone 1 regulation of hemoglobin biosynthetic process 1 regulation of high voltage-gated calcium channel activity 1 regulation of histone ubiquitination 1 regulation of immune system process 1 regulation of innate immune response 1 regulation of insulin receptor signaling pathway 1 regulation of integrin biosynthetic process 1 regulation of interferon-gamma-mediated signaling pathway 1 regulation of intrinsic apoptotic signaling pathway 1 regulation of intrinsic apoptotic signaling pathway by p53 class mediator 1 regulation of ion transmembrane transporter activity 1 regulation of JAK-STAT cascade 1 regulation of L-arginine import 1 regulation of long-term neuronal synaptic plasticity 1 regulation of low-density lipoprotein particle receptor biosynthetic process 1 regulation of macrophage apoptotic process 1 regulation of membrane potential 1 regulation of membrane repolarization 1 regulation of microtubule-based movement 1 regulation of microtubule-based process 1 regulation of microtubule cytoskeleton organization 1 regulation of miRNA metabolic process 1 regulation of mitochondrial DNA replication 1 regulation of mitochondrial membrane permeability involved in apoptotic process 1 regulation of mitochondrial translation 1 regulation of mitochondrion degradation 1 regulation of mitotic cell cycle phase transition 1 regulation of mitotic cell cycle spindle assembly checkpoint 1 regulation of mitotic centrosome separation 1 regulation of mitotic metaphase/anaphase transition 1 regulation of mitotic recombination 1 regulation of mitotic sister chromatid separation 1 regulation of mRNA 3'-end processing 1 regulation of mRNA stability 1 regulation of myotube differentiation 1 regulation of neurogenesis 1 regulation of nucleocytoplasmic transport 1 regulation of nucleotide-excision repair 1 regulation of organ growth 1 regulation of ossification 1 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway 1 regulation of potassium ion transmembrane transporter activity 1 regulation of protein autophosphorylation 1 regulation of protein complex assembly 1 regulation of protein exit from endoplasmic reticulum 1 regulation of protein homodimerization activity 1 regulation of protein import into nucleus, translocation 1 regulation of protein kinase A signaling 1 regulation of protein kinase C signaling 1 regulation of protein localization to nucleus 1 regulation of protein metabolic process 1 regulation of protein monoubiquitination 1 regulation of protein secretion 1 regulation of protein targeting to mitochondrion 1 regulation of protein ubiquitination 1 regulation of Rab GTPase activity 1 regulation of Rac GTPase activity 1 regulation of Rac protein signal transduction 1 regulation of receptor activity 1 regulation of respiratory gaseous exchange by neurological system process 1 regulation of ruffle assembly 1 regulation of skeletal muscle fiber development 1 regulation of smooth muscle cell migration 1 regulation of smooth muscle contraction 1 regulation of smoothened signaling pathway 1 regulation of spindle assembly involved in mitosis 1 regulation of spindle checkpoint 1 regulation of stem cell proliferation 1 regulation of stress-activated MAPK cascade 1 regulation of synaptic vesicle endocytosis 1 regulation of systemic arterial blood pressure by baroreceptor feedback 1 regulation of T cell differentiation in thymus 1 regulation of telomere maintenance 1 regulation of thymocyte apoptotic process 1 regulation of tissue remodeling 1 regulation of transcription from RNA polymerase I promoter 1 regulation of transforming growth factor beta receptor signaling pathway 1 regulation of ubiquitin-protein transferase activity 1 regulation of vascular wound healing 1 regulation of vasoconstriction 1 regulation of vesicle-mediated transport 1 regulation of viral process 1 repressing transcription factor binding 1 respiratory burst involved in defense response 1 respiratory chain 1 response to aluminum ion 1 response to amino acid 1 response to antipsychotic drug 1 response to ATP 1 response to cadmium ion 1 response to caffeine 1 response to carbon monoxide 1 response to copper ion 1 response to corticosteroid 1 response to corticosterone 1 response to cortisol 1 response to DDT 1 response to extracellular stimulus 1 response to folic acid 1 response to food 1 response to glucagon 1 response to growth hormone 1 response to herbicide 1 response to hydrostatic pressure 1 response to insecticide 1 response to interferon-gamma 1 response to magnetism 1 response to manganese ion 1 response to morphine 1 response to muramyl dipeptide 1 response to nicotine 1 response to organophosphorus 1 response to osmotic stress 1 response to pH 1 response to progesterone 1 response to selenium ion 1 response to starvation 1 response to stimulus 1 response to vitamin A 1 retinoic acid binding 1 retinoid metabolic process 1 retinoid X receptor binding 1 retrograde protein transport, ER to cytosol 1 ribbon synapse 1 ribonuclease inhibitor activity 1 ribonuclease MRP activity 1 ribonuclease MRP complex 1 ribonucleoside monophosphate biosynthetic process 1 ribose phosphate biosynthetic process 1 ribose phosphate metabolic process 1 ribosomal large subunit binding 1 ribosomal protein import into nucleus 1 ribosomal small subunit assembly 1 ripoptosome assembly involved in necroptotic process 1 RNA-3'-phosphate cyclase activity 1 RNA-dependent ATPase activity 1 RNA-directed RNA polymerase activity 1 RNA catabolic process 1 RNA export from nucleus 1 RNA import into nucleus 1 RNA localization 1 RNA polymerase I CORE element sequence-specific DNA binding 1 RNA polymerase I CORE element sequence-specific DNA binding transcription factor recruiting transcription factor activity 1 RNA polymerase I core factor complex 1 RNA polymerase I transcription factor binding 1 RNA polymerase I transcription factor complex 1 RNA polymerase II activating transcription factor binding 1 RNA polymerase II core binding 1 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription 1 RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription 1 RNA polymerase transcription factor SL1 complex 1 RNA secondary structure unwinding 1 RNA stem-loop binding 1 RNA transport 1 RNA uridylyltransferase activity 1 rostrocaudal neural tube patterning 1 rRNA catabolic process 1 RS domain binding 1 ruffle organization 1 S-adenosylhomocysteine catabolic process 1 SAGA complex 1 sarcomerogenesis 1 sarcoplasmic reticulum membrane 1 satellite DNA binding 1 scavenger receptor activity 1 SCF complex assembly 1 Scrib-APC-beta-catenin complex 1 secretion 1 secretory granule localization 1 selenium binding 1 selenocysteinyl-tRNA(Sec) biosynthetic process 1 sensory perception of smell 1 sensory perception of temperature stimulus 1 sequence-specific DNA binding RNA polymerase II transcription factor activity 1 sequestering of calcium ion 1 sequestering of zinc ion 1 serine-type carboxypeptidase activity 1 serotonin metabolic process 1 sesquiterpenoid metabolic process 1 Set1C/COMPASS complex 1 SH2 domain binding 1 signal recognition particle 1 signal recognition particle binding 1 signal recognition particle receptor complex 1 signal recognition particle, endoplasmic reticulum targeting 1 signal transduction by phosphorylation 1 signal transduction involved in mitotic G1 DNA damage checkpoint 1 signal transduction involved in regulation of gene expression 1 Sin3 complex 1 single-stranded DNA endodeoxyribonuclease activity 1 single fertilization 1 single strand break repair 1 skeletal muscle cell differentiation 1 skeletal muscle fiber adaptation 1 slit diaphragm 1 SMAD protein import into nucleus 1 SMAD protein signal transduction 1 small GTPase binding 1 small GTPase regulator activity 1 smooth muscle contractile fiber 1 snoRNA metabolic process 1 snRNA metabolic process 1 snRNA modification 1 snRNA processing 1 snRNP binding 1 sodium-independent organic anion transport 1 sodium channel regulator activity 1 sodium ion transmembrane transport 1 sodium:dicarboxylate symporter activity 1 somatic diversification of immune receptors via somatic mutation 1 somatic recombination of immunoglobulin genes involved in immune response 1 somatic stem cell maintenance 1 spectrin-associated cytoskeleton 1 spectrin binding 1 sperm chromatin condensation 1 sperm fibrous sheath 1 sperm principal piece 1 spinal cord motor neuron differentiation 1 spindle pole centrosome 1 stem cell differentiation 1 steroid binding 1 steroid biosynthetic process 1 sterol regulatory element binding protein import into nucleus 1 stress fiber assembly 1 striated muscle cell development 1 striated muscle cell differentiation 1 striatum development 1 structural constituent of cell wall 1 structural constituent of eye lens 1 structural molecule activity conferring elasticity 1 succinate-CoA ligase complex (GDP-forming) 1 succinate metabolic process 1 sulfonylurea receptor binding 1 sulfur amino acid metabolic process 1 SUMO-specific isopeptidase activity 1 superoxide anion generation 1 SWI/SNF complex 1 SWI/SNF superfamily-type complex 1 symporter activity 1 synapse assembly 1 synaptic vesicle exocytosis 1 synaptic vesicle targeting 1 synaptonemal complex 1 synaptonemal complex disassembly 1 syntrophin complex 1 T cell chemotaxis 1 T cell costimulation 1 T cell proliferation involved in immune response 1 T cell receptor V(D)J recombination 1 tangential migration from the subventricular zone to the olfactory bulb 1 targeting of mRNA for destruction involved in RNA interference 1 Tat protein binding 1 TCTN-B9D complex 1 telethonin binding 1 termination of G-protein coupled receptor signaling pathway 1 testosterone dehydrogenase [NAD(P)] activity 1 tetrahydrobiopterin biosynthetic process 1 tetrahydrofolate metabolic process 1 tetrapyrrole binding 1 thalamus development 1 thiamine pyrophosphate binding 1 thioesterase binding 1 third ventricle development 1 thromboxane A2 receptor binding 1 thymus development 1 thyrotropin-releasing hormone receptor binding 1 tissue homeostasis 1 titin binding 1 tolerance induction to lipopolysaccharide 1 Toll-like receptor 4 binding 1 tongue morphogenesis 1 TOR signaling 1 TORC1 complex 1 trans-Golgi network transport vesicle 1 transaminase activity 1 transcription factor TFIIA complex 1 transcription, RNA-templated 1 transcriptional activation by promoter-enhancer looping 1 transcriptional repressor complex 1 transferase activity 1 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer 1 transferrin transport 1 transforming growth factor beta receptor binding 1 transition between slow and fast fiber 1 translation regulator activity 1 translation release factor activity, codon specific 1 translation repressor activity 1 translation termination factor activity 1 translocation of peptides or proteins into host cell cytoplasm 1 transmembrane receptor protein tyrosine phosphatase signaling pathway 1 transmembrane signaling receptor activity 1 triglyceride metabolic process 1 tRNA (adenine-N1-)-methyltransferase activity 1 tRNA (guanine-N7-)-methyltransferase activity 1 tRNA (m1A) methyltransferase complex 1 tRNA 5'-leader removal 1 tRNA catabolic process 1 tRNA guanylyltransferase activity 1 tRNA methylation 1 tRNA modification 1 trophectodermal cellular morphogenesis 1 tropomyosin binding 1 tryptophan transport 1 tubulin complex assembly 1 type 3 metabotropic glutamate receptor binding 1 type I interferon production 1 U1 snRNP 1 U2 snRNP 1 U4 snRNP 1 U4atac snRNP 1 U5 snRNA binding 1 U6 snRNA binding 1 UBC13-MMS2 complex 1 UBC13-UEV1A complex 1 ubiquinone biosynthetic process 1 ubiquitin-dependent SMAD protein catabolic process 1 ubiquitin conjugating enzyme complex 1 ubiquitin protein ligase activity 1 UDP-glucosylation 1 urea cycle 1 ureteric bud development 1 uropod organization 1 UTP binding 1 UV protection 1 vagus nerve development 1 valine catabolic process 1 valyl-tRNA aminoacylation 1 vasodilation 1 very-low-density lipoprotein particle assembly 1 very long-chain fatty-acyl-CoA metabolic process 1 very long-chain fatty acid catabolic process 1 very long-chain fatty acid metabolic process 1 vesicle coat 1 vesicle membrane 1 virion binding 1 virus receptor activity 1 visual behavior 1 vitamin B6 metabolic process 1 vitamin binding 1 vitamin D receptor binding 1 vocalization behavior 1 water transport 1 WD40-repeat domain binding 1 Y-form DNA binding 1 zonula adherens maintenance 1