data_global
_audit_creation_method                  'APEX3 v2017.3-0'

_publ_requested_journal                 ?

_publ_contact_author_name               ?
_publ_contact_author_address            
;
;
_publ_contact_author_email              ?
_publ_contact_author_fax                ?
_publ_contact_author_phone              ?

_publ_section_title                     
;
;
_publ_section_abstract                  
;
;
_publ_section_references                
;
;
_publ_section_comment                   
;
;

data_LMJG43
_chemical_name_systematic               ?
_chemical_name_common                   ?
_chemical_formula_moiety                ?
_chemical_formula_sum                   'C29 H39 O10'
_chemical_formula_iupac                 ?
_chemical_formula_weight                547.60
_chemical_absolute_configuration        ad

_chemical_melting_point                 ?

_space_group_crystal_system             orthorhombic
_space_group_name_H-M_alt               'P 21 21 21'
_space_group_name_Hall                  'P 2ac 2ab'
loop_
    _space_group_symop_operation_xyz
    'x, y, z'
    'x+1/2, -y+1/2, -z'
    '-x, y+1/2, -z+1/2'
    '-x+1/2, -y, z+1/2'

_cell_length_a                          9.2386(2)
_cell_length_b                          11.0791(2)
_cell_length_c                          26.7495(6)
_cell_angle_alpha                       90
_cell_angle_beta                        90
_cell_angle_gamma                       90
_cell_volume                            2737.96(10)
_cell_formula_units_Z                   4
_cell_measurement_reflns_used           9908
_cell_measurement_theta_min             4.7866
_cell_measurement_theta_max             78.9752
_cell_measurement_temperature           298.(2)

_exptl_crystal_description              BLOCK
_exptl_crystal_colour                   'clear light colourless'
_exptl_crystal_size_max                 0.244
_exptl_crystal_size_mid                 0.209
_exptl_crystal_size_min                 0.137
_exptl_crystal_density_diffrn           1.328
_exptl_crystal_density_meas             ?
_exptl_crystal_density_method           'not measured'
_exptl_crystal_F_000                    1172

_exptl_absorpt_coefficient_mu           0.829
_exptl_absorpt_correction_type          Multi-Scan
_exptl_absorpt_process_details          
;
SADABS-2016/2 - Bruker AXS area detector scaling and absorption correction
;
_exptl_absorpt_correction_T_min         0.81
_exptl_absorpt_correction_T_max         0.90

_exptl_special_details                  
;
; 

_diffrn_ambient_temperature             298.(2)

_diffrn_source                          ?
_diffrn_source_type                     ?

_diffrn_radiation_type                 'Cu K\a'
_diffrn_radiation_wavelength            1.54178
_diffrn_radiation_monochromator         ?

_diffrn_measurement_device_type         'Bruker APEX-II CCD'
_diffrn_measurement_method              'φ and ω scans' 

_diffrn_detector_area_resol_mean        7.3910

_diffrn_reflns_number                   49153
_diffrn_reflns_av_R_equivalents         0.0586
_diffrn_reflns_av_unetI/netI            0.0411
_diffrn_reflns_theta_min                3.30
_diffrn_reflns_theta_max                79.42
_diffrn_reflns_theta_full               79.42
_diffrn_measured_fraction_theta_max     0.998
_diffrn_measured_fraction_theta_full    0.998
_diffrn_reflns_limit_h_min              -10
_diffrn_reflns_limit_h_max              11
_diffrn_reflns_limit_k_min              -14
_diffrn_reflns_limit_k_max              14
_diffrn_reflns_limit_l_min              -29
_diffrn_reflns_limit_l_max              34

_refine_special_details                 
;
;

_reflns_number_total                    5918
_reflns_number_gt                       5552
_reflns_threshold_expression            'I > 2σ(I)'

_refine_ls_structure_factor_coef        Fsqd
_refine_ls_matrix_type                  full
_refine_ls_R_factor_all                 0.0417
_refine_ls_R_factor_gt                  0.0385
_refine_ls_wR_factor_gt                 0.0943
_refine_ls_wR_factor_ref                0.0972
_refine_ls_goodness_of_fit_ref          1.062
_refine_ls_restrained_S_all             1.062
_refine_ls_number_reflns                5918
_refine_ls_number_parameters            366
_refine_ls_number_restraints            0
_refine_ls_number_constraints           ?
_refine_ls_hydrogen_treatment           mixed
_refine_ls_weighting_scheme             calc
_refine_ls_weighting_details            
    'w=1/[σ²(Fo²)+(0.0507P)²+0.2326P] where P=(Fo²+2Fc²)/3'

_atom_sites_solution_hydrogens          mixed
_atom_sites_solution_primary            ?
_atom_sites_solution_secondary          ?

_refine_ls_shift/su_max                 0.001
_refine_ls_shift/su_mean                0.000
_refine_diff_density_max                0.293
_refine_diff_density_min                -0.152
_refine_ls_extinction_method            none
_refine_ls_extinction_coef              ?
_refine_ls_abs_structure_details        
;

Flack x determined using 2280 quotients [(I+)-(I-)]/[(I+)+(I-)]
(Parsons, Flack and Wagner, Acta Cryst. B69 (2013) 249-259).
;
_refine_ls_abs_structure_Flack          -0.03(6)

loop_
    _atom_type_symbol
    _atom_type_description
    _atom_type_scat_dispersion_real
    _atom_type_scat_dispersion_imag
    _atom_type_scat_source
    C C 0.0181 0.0091 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4'
    H H 0.0000 0.0000 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4'
    O O 0.0492 0.0322 'International Tables Vol C Tables 4.2.6.8 and 6.1.1.4'

_computing_data_collection              ?
_computing_cell_refinement              'SAINT V8.38A (Bruker AXS Inc., 2017)'
_computing_data_reduction               'SAINT V8.38A (Bruker AXS Inc., 2017)'
_computing_structure_solution           'SHELXT 2014/5 (Sheldrick, 2014)'
_computing_structure_refinement         'SHELXL-2016/6 (Sheldrick, 2016)'
_computing_molecular_graphics           'shelXle (C.B. Huebschle, rev 833)'
_computing_publication_material         ?

loop_
    _atom_site_type_symbol
    _atom_site_label
    _atom_site_fract_x
    _atom_site_fract_y
    _atom_site_fract_z
    _atom_site_U_iso_or_equiv
    _atom_site_adp_type
    _atom_site_calc_flag
    _atom_site_refinement_flags_adp
    _atom_site_refinement_flags_occupancy
    _atom_site_refinement_flags_posn
    _atom_site_occupancy
    _atom_site_disorder_assembly
    _atom_site_disorder_group
    O O1 0.44421(14) 0.51520(16) 0.53513(5) 0.0437(3) Uani d . . . 1 . .
    H H9O 0.026(7) 0.672(6) 0.784(2) 0.110(18) Uiso d . . . 1 . .
    C C1 0.2903(2) 0.5060(2) 0.52418(7) 0.0417(4) Uani d . . . 1 . .
    H H1 0.261176 0.578903 0.506024 0.05 Uiso calc U . R 1 . .
    C C2 0.2677(3) 0.3984(3) 0.48995(8) 0.0556(6) Uani d . . . 1 . .
    H H2 0.258384 0.416652 0.454246 0.067 Uiso calc U . R 1 . .
    O O2 0.4807(2) 0.6081(4) 0.46283(10) 0.1164(15) Uani d . . . 1 . .
    O O3 0.3508(2) 0.2922(2) 0.50230(8) 0.0691(5) Uani d . . . 1 . .
    H H5O 0.191(8) 0.245(7) 0.682(3) 0.13(2) Uiso d . . . 1 . .
    C C3 0.1948(3) 0.2889(3) 0.50719(10) 0.0625(7) Uani d . . . 1 . .
    H H3 0.142641 0.242699 0.48166 0.075 Uiso calc U . R 1 . .
    O O4 0.35135(16) 0.33723(15) 0.60854(6) 0.0461(3) Uani d . . . 1 . .
    C C4 0.1402(3) 0.2764(3) 0.55977(9) 0.0553(5) Uani d . . . 1 . .
    H H4A 0.162749 0.19613 0.571939 0.066 Uiso calc U . R 1 . .
    H H4B 0.035775 0.285335 0.559833 0.066 Uiso calc U . R 1 . .
    O O5 0.1246(2) 0.24562(15) 0.66555(7) 0.0505(4) Uani d . . . 1 . .
    C C5 0.2064(2) 0.37014(19) 0.59537(7) 0.0392(4) Uani d . . . 1 . .
    O O6 0.2596(2) 0.41904(15) 0.71776(6) 0.0524(4) Uani d . . . 1 . .
    C C6 0.1238(2) 0.36389(18) 0.64584(7) 0.0394(4) Uani d . . . 1 . .
    H H6 0.023237 0.38858 0.640239 0.047 Uiso calc U . R 1 . .
    O O7 0.47643(14) 0.79483(14) 0.64191(5) 0.0404(3) Uani d . . . 1 . .
    C C7 0.1942(2) 0.45308(18) 0.68100(7) 0.0370(4) Uani d . . . 1 . .
    O O8 0.5380(3) 0.9053(3) 0.57515(10) 0.0910(9) Uani d . . . 1 . .
    C C8 0.18352(18) 0.58176(17) 0.66348(6) 0.0325(3) Uani d . . . 1 . .
    H H8 0.081418 0.602471 0.658476 0.039 Uiso calc U . R 1 . .
    C C9 0.26480(17) 0.59049(16) 0.61225(6) 0.0320(3) Uani d . . . 1 . .
    H H9 0.365232 0.566239 0.618431 0.038 Uiso calc U . R 1 . .
    O O9 0.05079(19) 0.6391(2) 0.75619(7) 0.0609(5) Uani d . . . 1 . .
    C C10 0.20200(18) 0.50022(18) 0.57342(6) 0.0351(3) Uani d . . . 1 . .
    O O10 0.2505(3) 0.9981(3) 0.86561(10) 0.0849(7) Uani d . . . 1 . .
    C C11 0.2691(2) 0.72161(18) 0.59349(7) 0.0385(4) Uani d . . . 1 . .
    H H11A 0.331278 0.725273 0.564312 0.046 Uiso calc U . R 1 . .
    H H11B 0.172425 0.744461 0.582975 0.046 Uiso calc U . R 1 . .
    C C12 0.32279(19) 0.81411(17) 0.63169(7) 0.0367(4) Uani d . . . 1 . .
    H H12 0.309385 0.895459 0.618075 0.044 Uiso calc U . R 1 . .
    C C13 0.24129(18) 0.80422(16) 0.68168(7) 0.0343(3) Uani d . . . 1 . .
    C C16 0.23016(19) 0.80137(18) 0.77171(7) 0.0388(4) Uani d . . . 1 . .
    H H16 0.136233 0.841289 0.775782 0.047 Uiso calc U . R 1 . .
    C C15 0.2003(2) 0.67065(19) 0.75417(7) 0.0401(4) Uani d . . . 1 . .
    H H15 0.257924 0.613354 0.773733 0.048 Uiso calc U . R 1 . .
    C C14 0.25078(18) 0.67145(16) 0.69941(6) 0.0319(3) Uani d . . . 1 . .
    H H14 0.354236 0.652022 0.700313 0.038 Uiso calc U . R 1 . .
    C C17 0.30930(19) 0.86468(18) 0.72820(8) 0.0374(4) Uani d . . . 1 . .
    H H17 0.410689 0.838879 0.729573 0.045 Uiso calc U . R 1 . .
    C C18 0.0856(2) 0.8498(2) 0.67268(9) 0.0463(4) Uani d . . . 1 . .
    H H18A 0.088158 0.933559 0.663575 0.069 Uiso calc U . R 1 . .
    H H18B 0.029846 0.84008 0.70269 0.069 Uiso calc U . R 1 . .
    H H18C 0.042074 0.804019 0.646177 0.069 Uiso calc U . R 1 . .
    C C19 0.0457(2) 0.5343(2) 0.55750(8) 0.0461(5) Uani d . . . 1 . .
    H H19A 0.043504 0.616966 0.546826 0.069 Uiso calc U . R 1 . .
    H H19B -0.018586 0.523757 0.585354 0.069 Uiso calc U . R 1 . .
    H H19C 0.015547 0.483104 0.530471 0.069 Uiso calc U . R 1 . .
    C C20 0.3079(2) 1.0016(2) 0.73572(10) 0.0493(5) Uani d . . . 1 . .
    H H20 0.207603 1.030118 0.734593 0.059 Uiso calc U . R 1 . .
    C C26 0.5268(3) 0.5693(3) 0.50059(9) 0.0569(6) Uani d . . . 1 . .
    C C25 0.2599(3) 0.7447(3) 0.86509(9) 0.0616(6) Uani d . . . 1 . .
    H H25A 0.15763 0.756906 0.868857 0.092 Uiso calc U . R 1 . .
    H H25B 0.308705 0.770258 0.894963 0.092 Uiso calc U . R 1 . .
    H H25C 0.278968 0.660709 0.85932 0.092 Uiso calc U . R 1 . .
    C C24 0.3145(2) 0.8181(2) 0.82101(8) 0.0488(5) Uani d . . . 1 . .
    H H24 0.415554 0.79559 0.814936 0.059 Uiso calc U . R 1 . .
    C C23 0.3087(3) 0.9534(3) 0.82947(10) 0.0580(6) Uani d . . . 1 . .
    C C22 0.3715(3) 1.0284(3) 0.78833(12) 0.0624(7) Uani d . . . 1 . .
    H H22A 0.475271 1.015312 0.787336 0.075 Uiso calc U . R 1 . .
    H H22B 0.355385 1.112925 0.796057 0.075 Uiso calc U . R 1 . .
    C C21 0.3962(3) 1.0699(2) 0.69658(14) 0.0664(7) Uani d . . . 1 . .
    H H21A 0.349149 1.063919 0.664681 0.1 Uiso calc U . R 1 . .
    H H21B 0.491353 1.035512 0.694414 0.1 Uiso calc U . R 1 . .
    H H21C 0.403516 1.153263 0.706066 0.1 Uiso calc U . R 1 . .
    C C28 0.5714(2) 0.8493(3) 0.61152(10) 0.0553(6) Uani d . . . 1 . .
    C C27 0.6819(3) 0.5716(4) 0.51571(12) 0.0739(9) Uani d . . . 1 . .
    H H27A 0.740833 0.544259 0.488399 0.111 Uiso calc U . R 1 . .
    H H27B 0.695944 0.519516 0.54398 0.111 Uiso calc U . R 1 . .
    H H27C 0.709035 0.652523 0.524502 0.111 Uiso calc U . R 1 . .
    C C29 0.7231(3) 0.8299(4) 0.62960(14) 0.0748(9) Uani d . . . 1 . .
    H H29A 0.74643 0.745564 0.627841 0.112 Uiso calc U . R 1 . .
    H H29B 0.731226 0.857009 0.663569 0.112 Uiso calc U . R 1 . .
    H H29C 0.789006 0.874723 0.608956 0.112 Uiso calc U . R 1 . .


_geom_special_details                   
;

All esds (except the esd in the dihedral angle between two l.s. planes)
are estimated using the full covariance matrix.  The cell esds are taken
into account individually in the estimation of esds in distances, angles
and torsion angles; correlations between esds in cell parameters are only
used when they are defined by crystal symmetry.  An approximate (isotropic)
treatment of cell esds is used for estimating esds involving l.s. planes.
;

loop_
    _geom_bond_atom_site_label_1
    _geom_bond_atom_site_label_2
    _geom_bond_site_symmetry_2
    _geom_bond_distance
    _geom_bond_publ_flag
    O1 C26 . 1.340(3) ?
    O1 C1 . 1.455(2) ?
    C1 C2 . 1.518(3) ?
    C1 C10 . 1.551(2) ?
    C1 H1 . 0.98 ?
    C2 O3 . 1.443(4) ?
    C2 C3 . 1.462(4) ?
    C2 H2 . 0.98 ?
    O2 C26 . 1.177(3) ?
    O3 C3 . 1.447(4) ?
    C3 C4 . 1.501(3) ?
    C3 H3 . 0.98 ?
    O4 C5 . 1.432(2) ?
    C4 C5 . 1.536(3) ?
    C4 H4A . 0.97 ?
    C4 H4B . 0.97 ?
    O5 C6 . 1.412(3) ?
    O5 H5O . 0.75(7) ?
    C5 C6 . 1.552(2) ?
    C5 C10 . 1.557(3) ?
    O6 C7 . 1.214(3) ?
    C6 C7 . 1.511(3) ?
    C6 H6 . 0.98 ?
    O7 C28 . 1.340(3) ?
    O7 C12 . 1.461(2) ?
    C7 C8 . 1.504(3) ?
    O8 C28 . 1.194(4) ?
    C8 C14 . 1.516(2) ?
    C8 C9 . 1.565(2) ?
    C8 H8 . 0.98 ?
    C9 C11 . 1.537(3) ?
    C9 C10 . 1.554(2) ?
    C9 H9 . 0.98 ?
    O9 C15 . 1.426(3) ?
    O9 H9O . 0.85(7) ?
    C10 C19 . 1.552(2) ?
    O10 C23 . 1.212(4) ?
    C11 C12 . 1.530(3) ?
    C11 H11A . 0.97 ?
    C11 H11B . 0.97 ?
    C12 C13 . 1.539(2) ?
    C12 H12 . 0.98 ?
    C13 C18 . 1.543(2) ?
    C13 C17 . 1.547(3) ?
    C13 C14 . 1.548(2) ?
    C16 C24 . 1.543(3) ?
    C16 C17 . 1.543(3) ?
    C16 C15 . 1.547(3) ?
    C16 H16 . 0.98 ?
    C15 C14 . 1.537(2) ?
    C15 H15 . 0.98 ?
    C14 H14 . 0.98 ?
    C17 C20 . 1.530(3) ?
    C17 H17 . 0.98 ?
    C18 H18A . 0.96 ?
    C18 H18B . 0.96 ?
    C18 H18C . 0.96 ?
    C19 H19A . 0.96 ?
    C19 H19B . 0.96 ?
    C19 H19C . 0.96 ?
    C20 C21 . 1.528(4) ?
    C20 C22 . 1.554(4) ?
    C20 H20 . 0.98 ?
    C26 C27 . 1.489(3) ?
    C25 C24 . 1.518(4) ?
    C25 H25A . 0.96 ?
    C25 H25B . 0.96 ?
    C25 H25C . 0.96 ?
    C24 C23 . 1.517(4) ?
    C24 H24 . 0.98 ?
    C23 C22 . 1.496(5) ?
    C22 H22A . 0.97 ?
    C22 H22B . 0.97 ?
    C21 H21A . 0.96 ?
    C21 H21B . 0.96 ?
    C21 H21C . 0.96 ?
    C28 C29 . 1.499(4) ?
    C27 H27A . 0.96 ?
    C27 H27B . 0.96 ?
    C27 H27C . 0.96 ?
    C29 H29A . 0.96 ?
    C29 H29B . 0.96 ?
    C29 H29C . 0.96 ?

loop_
    _geom_angle_atom_site_label_1
    _geom_angle_atom_site_label_2
    _geom_angle_atom_site_label_3
    _geom_angle_site_symmetry_1
    _geom_angle_site_symmetry_3
    _geom_angle
    _geom_angle_publ_flag
    C26 O1 C1 . . 116.68(16) ?
    O1 C1 C2 . . 108.11(18) ?
    O1 C1 C10 . . 110.25(14) ?
    C2 C1 C10 . . 114.05(18) ?
    O1 C1 H1 . . 108.1 ?
    C2 C1 H1 . . 108.1 ?
    C10 C1 H1 . . 108.1 ?
    O3 C2 C3 . . 59.7(2) ?
    O3 C2 C1 . . 115.4(2) ?
    C3 C2 C1 . . 121.66(19) ?
    O3 C2 H2 . . 116.0 ?
    C3 C2 H2 . . 116.0 ?
    C1 C2 H2 . . 116.0 ?
    C2 O3 C3 . . 60.8(2) ?
    O3 C3 C2 . . 59.47(19) ?
    O3 C3 C4 . . 114.9(2) ?
    C2 C3 C4 . . 121.8(2) ?
    O3 C3 H3 . . 116.1 ?
    C2 C3 H3 . . 116.1 ?
    C4 C3 H3 . . 116.1 ?
    C3 C4 C5 . . 112.7(2) ?
    C3 C4 H4A . . 109.1 ?
    C5 C4 H4A . . 109.1 ?
    C3 C4 H4B . . 109.1 ?
    C5 C4 H4B . . 109.1 ?
    H4A C4 H4B . . 107.8 ?
    C6 O5 H5O . . 103.(6) ?
    O4 C5 C4 . . 110.66(19) ?
    O4 C5 C6 . . 103.57(15) ?
    C4 C5 C6 . . 108.25(16) ?
    O4 C5 C10 . . 110.68(15) ?
    C4 C5 C10 . . 112.42(18) ?
    C6 C5 C10 . . 110.88(16) ?
    O5 C6 C7 . . 111.84(17) ?
    O5 C6 C5 . . 111.32(17) ?
    C7 C6 C5 . . 107.47(15) ?
    O5 C6 H6 . . 108.7 ?
    C7 C6 H6 . . 108.7 ?
    C5 C6 H6 . . 108.7 ?
    C28 O7 C12 . . 117.17(17) ?
    O6 C7 C8 . . 125.42(18) ?
    O6 C7 C6 . . 121.01(19) ?
    C8 C7 C6 . . 113.42(16) ?
    C7 C8 C14 . . 113.38(14) ?
    C7 C8 C9 . . 107.45(14) ?
    C14 C8 C9 . . 108.54(13) ?
    C7 C8 H8 . . 109.1 ?
    C14 C8 H8 . . 109.1 ?
    C9 C8 H8 . . 109.1 ?
    C11 C9 C10 . . 113.54(14) ?
    C11 C9 C8 . . 110.88(14) ?
    C10 C9 C8 . . 111.48(13) ?
    C11 C9 H9 . . 106.8 ?
    C10 C9 H9 . . 106.8 ?
    C8 C9 H9 . . 106.8 ?
    C15 O9 H9O . . 101.(4) ?
    C1 C10 C19 . . 104.27(15) ?
    C1 C10 C9 . . 110.16(14) ?
    C19 C10 C9 . . 111.98(16) ?
    C1 C10 C5 . . 110.18(16) ?
    C19 C10 C5 . . 110.67(16) ?
    C9 C10 C5 . . 109.49(14) ?
    C12 C11 C9 . . 115.04(15) ?
    C12 C11 H11A . . 108.5 ?
    C9 C11 H11A . . 108.5 ?
    C12 C11 H11B . . 108.5 ?
    C9 C11 H11B . . 108.5 ?
    H11A C11 H11B . . 107.5 ?
    O7 C12 C11 . . 110.00(15) ?
    O7 C12 C13 . . 107.60(14) ?
    C11 C12 C13 . . 111.97(15) ?
    O7 C12 H12 . . 109.1 ?
    C11 C12 H12 . . 109.1 ?
    C13 C12 H12 . . 109.1 ?
    C12 C13 C18 . . 107.29(15) ?
    C12 C13 C17 . . 118.01(15) ?
    C18 C13 C17 . . 111.26(16) ?
    C12 C13 C14 . . 107.83(14) ?
    C18 C13 C14 . . 114.29(16) ?
    C17 C13 C14 . . 98.17(14) ?
    C24 C16 C17 . . 110.54(16) ?
    C24 C16 C15 . . 117.49(18) ?
    C17 C16 C15 . . 106.34(15) ?
    C24 C16 H16 . . 107.3 ?
    C17 C16 H16 . . 107.3 ?
    C15 C16 H16 . . 107.3 ?
    O9 C15 C14 . . 109.36(16) ?
    O9 C15 C16 . . 113.02(17) ?
    C14 C15 C16 . . 103.26(15) ?
    O9 C15 H15 . . 110.3 ?
    C14 C15 H15 . . 110.3 ?
    C16 C15 H15 . . 110.3 ?
    C8 C14 C15 . . 118.43(14) ?
    C8 C14 C13 . . 113.92(14) ?
    C15 C14 C13 . . 106.27(15) ?
    C8 C14 H14 . . 105.7 ?
    C15 C14 H14 . . 105.7 ?
    C13 C14 H14 . . 105.7 ?
    C20 C17 C16 . . 110.34(17) ?
    C20 C17 C13 . . 122.13(18) ?
    C16 C17 C13 . . 102.56(14) ?
    C20 C17 H17 . . 107.0 ?
    C16 C17 H17 . . 107.0 ?
    C13 C17 H17 . . 107.0 ?
    C13 C18 H18A . . 109.5 ?
    C13 C18 H18B . . 109.5 ?
    H18A C18 H18B . . 109.5 ?
    C13 C18 H18C . . 109.5 ?
    H18A C18 H18C . . 109.5 ?
    H18B C18 H18C . . 109.5 ?
    C10 C19 H19A . . 109.5 ?
    C10 C19 H19B . . 109.5 ?
    H19A C19 H19B . . 109.5 ?
    C10 C19 H19C . . 109.5 ?
    H19A C19 H19C . . 109.5 ?
    H19B C19 H19C . . 109.5 ?
    C21 C20 C17 . . 113.4(2) ?
    C21 C20 C22 . . 108.9(2) ?
    C17 C20 C22 . . 107.8(2) ?
    C21 C20 H20 . . 108.9 ?
    C17 C20 H20 . . 108.9 ?
    C22 C20 H20 . . 108.9 ?
    O2 C26 O1 . . 123.3(2) ?
    O2 C26 C27 . . 125.1(2) ?
    O1 C26 C27 . . 111.6(2) ?
    C24 C25 H25A . . 109.5 ?
    C24 C25 H25B . . 109.5 ?
    H25A C25 H25B . . 109.5 ?
    C24 C25 H25C . . 109.5 ?
    H25A C25 H25C . . 109.5 ?
    H25B C25 H25C . . 109.5 ?
    C23 C24 C25 . . 113.7(2) ?
    C23 C24 C16 . . 103.2(2) ?
    C25 C24 C16 . . 115.6(2) ?
    C23 C24 H24 . . 108.0 ?
    C25 C24 H24 . . 108.0 ?
    C16 C24 H24 . . 108.0 ?
    O10 C23 C22 . . 122.1(3) ?
    O10 C23 C24 . . 122.6(3) ?
    C22 C23 C24 . . 115.2(2) ?
    C23 C22 C20 . . 114.4(2) ?
    C23 C22 H22A . . 108.7 ?
    C20 C22 H22A . . 108.7 ?
    C23 C22 H22B . . 108.7 ?
    C20 C22 H22B . . 108.7 ?
    H22A C22 H22B . . 107.6 ?
    C20 C21 H21A . . 109.5 ?
    C20 C21 H21B . . 109.5 ?
    H21A C21 H21B . . 109.5 ?
    C20 C21 H21C . . 109.5 ?
    H21A C21 H21C . . 109.5 ?
    H21B C21 H21C . . 109.5 ?
    O8 C28 O7 . . 124.0(2) ?
    O8 C28 C29 . . 125.4(2) ?
    O7 C28 C29 . . 110.6(2) ?
    C26 C27 H27A . . 109.5 ?
    C26 C27 H27B . . 109.5 ?
    H27A C27 H27B . . 109.5 ?
    C26 C27 H27C . . 109.5 ?
    H27A C27 H27C . . 109.5 ?
    H27B C27 H27C . . 109.5 ?
    C28 C29 H29A . . 109.5 ?
    C28 C29 H29B . . 109.5 ?
    H29A C29 H29B . . 109.5 ?
    C28 C29 H29C . . 109.5 ?
    H29A C29 H29C . . 109.5 ?
    H29B C29 H29C . . 109.5 ?

loop_
    _geom_torsion_atom_site_label_1
    _geom_torsion_atom_site_label_2
    _geom_torsion_atom_site_label_3
    _geom_torsion_atom_site_label_4
    _geom_torsion_site_symmetry_1
    _geom_torsion_site_symmetry_2
    _geom_torsion_site_symmetry_3
    _geom_torsion_site_symmetry_4
    _geom_torsion
    _geom_torsion_publ_flag
    C26 O1 C1 C2 . . . . 81.5(3) ?
    C26 O1 C1 C10 . . . . -153.2(2) ?
    O1 C1 C2 O3 . . . . 41.6(3) ?
    C10 C1 C2 O3 . . . . -81.4(2) ?
    O1 C1 C2 C3 . . . . 110.4(3) ?
    C10 C1 C2 C3 . . . . -12.6(3) ?
    C1 C2 O3 C3 . . . . 113.3(2) ?
    C2 O3 C3 C4 . . . . -113.6(3) ?
    C1 C2 C3 O3 . . . . -103.0(3) ?
    O3 C2 C3 C4 . . . . 102.2(3) ?
    C1 C2 C3 C4 . . . . -0.8(4) ?
    O3 C3 C4 C5 . . . . 51.6(4) ?
    C2 C3 C4 C5 . . . . -16.7(4) ?
    C3 C4 C5 O4 . . . . -76.9(3) ?
    C3 C4 C5 C6 . . . . 170.3(2) ?
    C3 C4 C5 C10 . . . . 47.5(3) ?
    O4 C5 C6 O5 . . . . -62.5(2) ?
    C4 C5 C6 O5 . . . . 55.0(2) ?
    C10 C5 C6 O5 . . . . 178.75(16) ?
    O4 C5 C6 C7 . . . . 60.3(2) ?
    C4 C5 C6 C7 . . . . 177.79(19) ?
    C10 C5 C6 C7 . . . . -58.5(2) ?
    O5 C6 C7 O6 . . . . 9.5(3) ?
    C5 C6 C7 O6 . . . . -112.9(2) ?
    O5 C6 C7 C8 . . . . -174.76(15) ?
    C5 C6 C7 C8 . . . . 62.8(2) ?
    O6 C7 C8 C14 . . . . -6.0(3) ?
    C6 C7 C8 C14 . . . . 178.51(14) ?
    O6 C7 C8 C9 . . . . 113.9(2) ?
    C6 C7 C8 C9 . . . . -61.55(18) ?
    C7 C8 C9 C11 . . . . -175.70(15) ?
    C14 C8 C9 C11 . . . . -52.74(18) ?
    C7 C8 C9 C10 . . . . 56.74(18) ?
    C14 C8 C9 C10 . . . . 179.70(14) ?
    O1 C1 C10 C19 . . . . 161.44(19) ?
    C2 C1 C10 C19 . . . . -76.7(2) ?
    O1 C1 C10 C9 . . . . 41.1(2) ?
    C2 C1 C10 C9 . . . . 162.95(18) ?
    O1 C1 C10 C5 . . . . -79.8(2) ?
    C2 C1 C10 C5 . . . . 42.0(2) ?
    C11 C9 C10 C1 . . . . 57.1(2) ?
    C8 C9 C10 C1 . . . . -176.80(15) ?
    C11 C9 C10 C19 . . . . -58.46(19) ?
    C8 C9 C10 C19 . . . . 67.65(19) ?
    C11 C9 C10 C5 . . . . 178.40(14) ?
    C8 C9 C10 C5 . . . . -55.49(18) ?
    O4 C5 C10 C1 . . . . 63.31(18) ?
    C4 C5 C10 C1 . . . . -61.0(2) ?
    C6 C5 C10 C1 . . . . 177.67(14) ?
    O4 C5 C10 C19 . . . . 178.10(16) ?
    C4 C5 C10 C19 . . . . 53.8(2) ?
    C6 C5 C10 C19 . . . . -67.55(19) ?
    O4 C5 C10 C9 . . . . -57.99(18) ?
    C4 C5 C10 C9 . . . . 177.69(16) ?
    C6 C5 C10 C9 . . . . 56.37(18) ?
    C10 C9 C11 C12 . . . . 176.91(14) ?
    C8 C9 C11 C12 . . . . 50.5(2) ?
    C28 O7 C12 C11 . . . . 86.7(2) ?
    C28 O7 C12 C13 . . . . -151.0(2) ?
    C9 C11 C12 O7 . . . . 68.01(19) ?
    C9 C11 C12 C13 . . . . -51.6(2) ?
    O7 C12 C13 C18 . . . . 168.71(16) ?
    C11 C12 C13 C18 . . . . -70.3(2) ?
    O7 C12 C13 C17 . . . . 42.2(2) ?
    C11 C12 C13 C17 . . . . 163.15(15) ?
    O7 C12 C13 C14 . . . . -67.73(18) ?
    C11 C12 C13 C14 . . . . 53.26(18) ?
    C24 C16 C15 O9 . . . . 112.0(2) ?
    C17 C16 C15 O9 . . . . -123.62(18) ?
    C24 C16 C15 C14 . . . . -129.96(17) ?
    C17 C16 C15 C14 . . . . -5.58(18) ?
    C7 C8 C14 C15 . . . . -54.3(2) ?
    C9 C8 C14 C15 . . . . -173.58(15) ?
    C7 C8 C14 C13 . . . . 179.67(15) ?
    C9 C8 C14 C13 . . . . 60.36(18) ?
    O9 C15 C14 C8 . . . . -33.5(2) ?
    C16 C15 C14 C8 . . . . -154.09(15) ?
    O9 C15 C14 C13 . . . . 96.15(19) ?
    C16 C15 C14 C13 . . . . -24.43(18) ?
    C12 C13 C14 C8 . . . . -60.53(18) ?
    C18 C13 C14 C8 . . . . 58.7(2) ?
    C17 C13 C14 C8 . . . . 176.47(13) ?
    C12 C13 C14 C15 . . . . 167.25(14) ?
    C18 C13 C14 C15 . . . . -73.56(19) ?
    C17 C13 C14 C15 . . . . 44.25(16) ?
    C24 C16 C17 C20 . . . . -66.6(2) ?
    C15 C16 C17 C20 . . . . 164.85(16) ?
    C24 C16 C17 C13 . . . . 161.85(16) ?
    C15 C16 C17 C13 . . . . 33.27(18) ?
    C12 C13 C17 C20 . . . . 74.3(2) ?
    C18 C13 C17 C20 . . . . -50.3(2) ?
    C14 C13 C17 C20 . . . . -170.42(17) ?
    C12 C13 C17 C16 . . . . -161.60(15) ?
    C18 C13 C17 C16 . . . . 73.78(19) ?
    C14 C13 C17 C16 . . . . -46.34(16) ?
    C16 C17 C20 C21 . . . . 174.8(2) ?
    C13 C17 C20 C21 . . . . -64.8(3) ?
    C16 C17 C20 C22 . . . . 54.1(2) ?
    C13 C17 C20 C22 . . . . 174.55(17) ?
    C1 O1 C26 O2 . . . . -0.3(5) ?
    C1 O1 C26 C27 . . . . -179.2(3) ?
    C17 C16 C24 C23 . . . . 64.0(2) ?
    C15 C16 C24 C23 . . . . -173.78(18) ?
    C17 C16 C24 C25 . . . . -171.33(19) ?
    C15 C16 C24 C25 . . . . -49.1(3) ?
    C25 C24 C23 O10 . . . . -8.1(4) ?
    C16 C24 C23 O10 . . . . 117.9(3) ?
    C25 C24 C23 C22 . . . . 175.8(2) ?
    C16 C24 C23 C22 . . . . -58.3(3) ?
    O10 C23 C22 C20 . . . . -122.4(3) ?
    C24 C23 C22 C20 . . . . 53.7(3) ?
    C21 C20 C22 C23 . . . . -171.7(2) ?
    C17 C20 C22 C23 . . . . -48.2(3) ?
    C12 O7 C28 O8 . . . . -5.1(4) ?
    C12 O7 C28 C29 . . . . 174.9(2) ?



