A Novel Chiral Pentamine Ligand for
Enantioselective α-Alkylation of Acyclic
Lithium Amide Enolates. Optimization of
Chiral Ligands for Asymmetric
Reactions Using Solid-Phase Organic
Synthesis
Posted on 1999-06-06 - 00:00
A novel pentamine ligand has been developed for enantioselective α-alkylation of simple acyclic lithium amide enolates. It has been demonstrated
that solid-phase organic synthesis provides a powerful and rapid method for finding efficient chiral ligands.
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Matsuo, Jun-ichi; Odashima, Kazunori; Kobayashi, Shū (2016). A Novel Chiral Pentamine Ligand for
Enantioselective α-Alkylation of Acyclic
Lithium Amide Enolates. Optimization of
Chiral Ligands for Asymmetric
Reactions Using Solid-Phase Organic
Synthesis. ACS Publications. Collection. https://doi.org/10.1021/ol990624d