Stereoselective Synthesis of the C1−C13
Fragment of 2,3-Dihydrodorrigocin A
Posted on 2005-09-30 - 00:00
The first synthesis of the C1−C13 fragment of 2,3-dihydrodorrigocin A has been achieved from 6-bromohexanoic acid
in 14 linear steps and an overall yield of 2%. The configurations of the stereogenic centers C8, C9, and C10 have been
determined to be the same as for migrastatin.
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Brazidec, Jean-Yves Le; Gilson, Charles A.; Boehm, Marcus F. (2016). Stereoselective Synthesis of the C1−C13
Fragment of 2,3-Dihydrodorrigocin A. ACS Publications. Collection. https://doi.org/10.1021/jo050942s