Transition-Metal-Free
One-Step Synthesis of Ynamides
Version 2 2019-03-15, 15:20
Version 1 2019-03-15, 15:20
Posted on 2019-03-15 - 15:20
A robust
transition-metal-free one-step strategy for the synthesis
of ynamides from sulfonamides and (Z)-1,2-dichloroalkenes
or alkynyl chlorides is presented. This method is not only effective
for internal ynamides but also amenable for terminal ynamides. Various
functional groups, even the vinyl moiety, are compatible, and thus,
this strategy offers the opportunity for further functionalization.
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Zeng, Xianzhu; Tu, Yongliang; Zhang, Zhenming; You, Changming; Wu, Jiao; Ye, Zhiying; et al. (2019). Transition-Metal-Free
One-Step Synthesis of Ynamides. ACS Publications. Collection. https://doi.org/10.1021/acs.joc.8b03192
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AUTHORS (7)
XZ
Xianzhu Zeng
YT
Yongliang Tu
ZZ
Zhenming Zhang
CY
Changming You
JW
Jiao Wu
ZY
Zhiying Ye
JZ
Junfeng Zhao