The first total synthesis of (−)-aurafuron A is presented. It features a Suzuki cross-coupling reaction and a high yielding anionic aldol addition as central carbon skeleton building reactions. The synthesis confirms the proposed structure including its configuration and allows for detailed SAR studies.
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Hartmann, Olaf; Kalesse, Markus (2016). The Total Synthesis of (−)-Aurafuron A. ACS Publications. Collection. https://doi.org/10.1021/ol3011387