The Development of a Facile Tandem Wolff/Cope Rearrangement for the
Synthesis of Fused Carbocyclic Skeletons

Stoltz, Brian M.

The Development of a Facile Tandem Wolff/Cope Rearrangement for the Synthesis of Fused Carbocyclic Skeletons

Posted on 2003-10-16 - 00:00

A set of mild processes for the conversion of vinyl cyclopropyl diazo ketones to highly functionalized cycloheptadienones and vinyl cyclopentenones by use of a target-inspired tandem Wolff/Cope rearrangement sequence is described. A divergent reaction course of the vinyl cyclopropyl diazo ketone substrates under sono- or photochemical activation provides good to excellent yields (55−98%) of the product cycloheptadienones and vinyl cyclopentenones.

CITE THIS COLLECTION

Sarpong, Richmond; Su, Julius T.; Stoltz, Brian M. (2016). The Development of a Facile Tandem Wolff/Cope Rearrangement for the Synthesis of Fused Carbocyclic Skeletons. ACS Publications. Collection. https://doi.org/10.1021/ja037587c

https://doi.org/10.1021/ja037587c

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