Synthesis of Selenyl-Substituted
Quinoline Derivatives
via Substrate-Controlled Three-Component Domino Reactions

Xu, Yan-Li

Synthesis of Selenyl-Substituted Quinoline Derivatives via Substrate-Controlled Three-Component Domino Reactions

Posted on 2023-01-12 - 08:19

A simple and efficient method for the preparation of selenyl-substituted quinoline derivatives through a C_Sp3–H selenylation of in situ-generated 3-acetyl quinoline has been developed. This protocol is easy to handle, scalable, and good functional group tolerant, providing a rapid method to 3-selenoacetyl quinoline and 3-diselenoacetyl quinoline derivatives.

CITE THIS COLLECTION

Sun, Shuang-Shuang; Mo, Zu-Yu; Chen, Yan-Yan; Xu, Yan-Li (2022). Synthesis of Selenyl-Substituted Quinoline Derivatives via Substrate-Controlled Three-Component Domino Reactions. ACS Publications. Collection. https://doi.org/10.1021/acs.joc.2c01260

https://doi.org/10.1021/acs.joc.2c01260

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