Solid-Phase
Detoxification of Chemical Warfare Agents
using Zirconium-Based Metal Organic Frameworks and the Moisture Effects:
Analyze via Digestion
Version 2 2019-05-31, 18:06
Version 1 2019-05-30, 20:43
Posted on 2019-05-31 - 18:06
Zirconium-based
metal organic frameworks (Zr-MOFs) are highly chemically
and thermally stable and have been of particular interest as reactive
sorbents for chemical warfare agent (CWA) removal due to their fast
and selective reactivity toward CWAs reported in buffer solutions.
However, we find that decontamination of neat CWAs directly on Zr-MOFs,
UiO-66, UiO-66-NH2, and NU-1000 is rather slow, and the
reactivity trend and products generated are very different from those
in solution. Furthermore, we show that their decontamination rates
are affected by the amount of moisture present in the MOFs. Although
the effects are minor for UiO-66-NH2 and NU-1000, the hydrolytic
activity of UiO-66 toward CWAs dramatically improves as the amount
of water present increases. Specifically, the initial hydrolysis rate
of methyl paraoxon by UiO-66 increases from 6 μmol/d with 0
wt % water loading to 140 μmol/d with 400 wt % water
loading. The results reported here suggest that decontamination of
CWAs by Zr-MOFs in solid phase behaves very differently than solution
decontamination. Additionally, we present for the first time a digestion
method for analyzing and quantifying solid-phase decontamination,
which is a daunting challenge itself due to the lack of a convenient
analytical method.
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Wang, Hui; Mahle, John J.; Tovar, Trenton M.; Peterson, Gregory W.; Hall, Morgan G.; DeCoste, Jared B.; et al. (2019). Solid-Phase
Detoxification of Chemical Warfare Agents
using Zirconium-Based Metal Organic Frameworks and the Moisture Effects:
Analyze via Digestion. ACS Publications. Collection. https://doi.org/10.1021/acsami.9b04927
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AUTHORS (8)
HW
Hui Wang
JM
John J. Mahle
TT
Trenton M. Tovar
GP
Gregory W. Peterson
MH
Morgan G. Hall
JD
Jared B. DeCoste
JB
James H. Buchanan
CK
Christopher J. Karwacki
KEYWORDS
digestion methodZr-MOFloadingSolid-Phase Detoxificationreactive sorbentsmolreactivity trendChemical Warfare AgentsUiO -66 increaseshydrolysis ratewtdecontamination ratesMOFchemical warfare agentbuffer solutionssolution decontaminationDigestion Zirconium-based metalUiO -66Zirconium-Based Metal Organic Frameworksquantifying solid-phase decontaminationMoisture Effectsmethyl paraoxonhydrolytic activityCWANU -1000UiO -66-NH 2