Selection and Functionalization of Germanium Nanowires for Bio-Sensing

Posted on 23.09.2022 - 07:07
In this paper, we investigate the use of dielectrophoresis to align germanium nanowire arrays to realize nanowire-based diodes and their subsequent use for bio-sensing. After establishing that dielectrophoresis is a controllable and repeatable fabrication method to create devices from germanium nanowires, we use the optimum process conditions to form a series of diodes. These are subsequently functionalized with an aptamer, which is able to bind specifically to the spike protein of SARS-Cov2 and investigated as a potential sensor. We observe a linear increase in the source to drain current as the concentration of spike protein is increased from 100 fM/L to 1 nM/L.

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Laumier, Siriny; Farrow, Thomas; van Zalinge, Harm; Seravalli, Luca; Bosi, Matteo; Sandall, Ian (2022): Selection and Functionalization of Germanium Nanowires for Bio-Sensing. ACS Publications. Collection. https://doi.org/10.1021/acsomega.2c04775
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