Palladium-Catalyzed Asymmetric Allylic Alkylation
of Alkyl-Substituted Allyl Reagents with Acyclic Amides
Posted on 2017-10-18 - 14:19
A wide range of alkyl-substituted
allyl reagents, as well as nonstabilized
carbon nucleophiles, was successfully used for the first time in the
palladium-catalyzed asymmetric allylic alkylation reaction, affording
the corresponding allylic alkylated products in high yields with high
enantioselectivities. The usefulness of the protocol has been demonstrated
by the enantioselective synthesis of an important chiral building
block and enantiomer of Dubiusamine A.
CITE THIS COLLECTION
DataCite
3 Biotech
3D Printing in Medicine
3D Research
3D-Printed Materials and Systems
4OR
AAPG Bulletin
AAPS Open
AAPS PharmSciTech
Abhandlungen aus dem Mathematischen Seminar der Universität Hamburg
ABI Technik (German)
Academic Medicine
Academic Pediatrics
Academic Psychiatry
Academic Questions
Academy of Management Discoveries
Academy of Management Journal
Academy of Management Learning and Education
Academy of Management Perspectives
Academy of Management Proceedings
Academy of Management Review
Jiang, Yang-Jie; Zhang, Gao-Peng; Huang, Jian-Qiang; Chen, Di; Ding, Chang-Hua; Hou, Xue-Long (2017). Palladium-Catalyzed Asymmetric Allylic Alkylation
of Alkyl-Substituted Allyl Reagents with Acyclic Amides. ACS Publications. Collection. https://doi.org/10.1021/acs.orglett.7b02927
or
Select your citation style and then place your mouse over the citation text to select it.
SHARE
Usage metrics
Read the peer-reviewed publication
AUTHORS (6)
YJ
Yang-Jie Jiang
GZ
Gao-Peng Zhang
JH
Jian-Qiang Huang
DC
Di Chen
CD
Chang-Hua Ding
XH
Xue-Long Hou
KEYWORDS
chiral building blockusefulnessDubiusamineAcyclic Amidesallylic alkylated productsAlkyl-Substituted Allyl Reagentsenantiomerenantioselective synthesisenantioselectivitieallylic alkylation reactionpalladium-catalyzedPalladium-Catalyzed Asymmetric Allylic Alkylationnonstabilized carbon nucleophilesalkyl-substituted allyl reagentsyield