One-Pot Friedel−Crafts/Robinson−Gabriel
Synthesis of Oxazoles Using Oxazolone
Templates

Tepe, Jetze J.

One-Pot Friedel−Crafts/Robinson−Gabriel Synthesis of Oxazoles Using Oxazolone Templates

Posted on 2005-05-13 - 00:00

We report herein a one-pot synthesis of 2,4,5-trisubstituted oxazoles via a Friedel−Crafts/Robinson−Gabriel synthesis using a general oxazolone template. Treatment of the oxazolone template with a range of aromatic nucleophiles provided the highly substituted oxazoles in good yields.

CITE THIS COLLECTION

Keni, Manasi; Tepe, Jetze J. (2016). One-Pot Friedel−Crafts/Robinson−Gabriel Synthesis of Oxazoles Using Oxazolone Templates. ACS Publications. Collection. https://doi.org/10.1021/jo0501590

https://doi.org/10.1021/jo0501590

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