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Oligomannan Synthesis Using Ionic Liquid Supported Glycosylation§

Posted on 2008-01-03 - 00:00
The synthesis of complex oligosaccharides has been a challenge for researchers. Herein, we describe a strategy for the synthesis of an activated oligomannan 1 that employs ionic liquid (IL) support glycosylation methodology on an IL-tagged mannosyl fluoride donor. This method is capable of rapidly producing linear α(1→6) oligomannan thioglycosides in a convenient and cost-effective manner without the need of column purification after each glycosylation step.

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