Oligomannan Synthesis Using Ionic
Liquid Supported Glycosylation§
Posted on 2008-01-03 - 00:00
The synthesis of complex oligosaccharides has been a challenge for researchers. Herein, we describe a strategy for the synthesis of an
activated oligomannan 1 that employs ionic liquid (IL) support glycosylation methodology on an IL-tagged mannosyl fluoride donor. This
method is capable of rapidly producing linear α(1→6) oligomannan thioglycosides in a convenient and cost-effective manner without the need
of column purification after each glycosylation step.