Nesteretal A, A Novel Class of Cage-Like Polyketide
from Marine-Derived Actinomycete Nesterenkonia halobia
Posted on 2019-08-17 - 18:13
An intriguing cage-like
polyhemiketal, nesteretal A (1), was isolated from the
coral-derived actinomycete Nesterenkonia halobia.
Its structure was established by extensive spectroscopic and computational
methods. Nesteretal A is a highly oxygenated compound featuring an
unprecedented 5/5/5/5 tetracyclic scaffold. A possible biosynthetic
pathway of 1 from naturally occurring diacetyl was proposed.
Compound 1 showed a weak retinoid X receptor-α
(RXRα) transcriptional activation effect.
CITE THIS COLLECTION
DataCite
3 Biotech
3D Printing in Medicine
3D Research
3D-Printed Materials and Systems
4OR
AAPG Bulletin
AAPS Open
AAPS PharmSciTech
Abhandlungen aus dem Mathematischen Seminar der Universität Hamburg
ABI Technik (German)
Academic Medicine
Academic Pediatrics
Academic Psychiatry
Academic Questions
Academy of Management Discoveries
Academy of Management Journal
Academy of Management Learning and Education
Academy of Management Perspectives
Academy of Management Proceedings
Academy of Management Review
Xie, Chun-Lan; Chen, Renzhi; Yang, Sihan; Xia, Jin-Mei; Zhang, Gai-Yun; Chen, Chao-Hong; et al. (2019). Nesteretal A, A Novel Class of Cage-Like Polyketide
from Marine-Derived Actinomycete Nesterenkonia halobia. ACS Publications. Collection. https://doi.org/10.1021/acs.orglett.9b02634
or
Select your citation style and then place your mouse over the citation text to select it.
SHARE
Usage metrics
Read the peer-reviewed publication
AUTHORS (8)
CX
Chun-Lan Xie
RC
Renzhi Chen
SY
Sihan Yang
JX
Jin-Mei Xia
GZ
Gai-Yun Zhang
CC
Chao-Hong Chen
YZ
Yandong Zhang
XY
Xian-Wen Yang
KEYWORDS
retinoid X receptor -αtranscriptionalCage-Like PolyketideNovel ClassNesteretalcoral-derived actinomycete Nesterenkonia halobiadiacetylscaffoldnesteretalactivationspectroscopicoxygenated compoundcage-like polyhemiketalbiosynthetic pathwayRXRCompound 1tetracyclicmethodMarine-Derived Actinomycete Nesterenkonia halobia