Manganese-Catalyzed Asymmetric Oxidation of Methylene C–H of Spirocyclic Oxindoles and Dihydroquinolinones with Hydrogen Peroxide

Published on 2019-01-11T19:53:49Z (GMT) by
A highly efficient strategy for the enantioselective oxidation of methylene C–H of spirocyclic oxindoles and dihydroquinolinones has been established, in which an earth-abundant manganese catalyst and hydrogen peroxide are used. Noteworthy, the manganese catalyst can be applied to the asymmetric hydroxylation of spirocyclic 2,3-dihydroquinolin-4-ones with 94–99% ee.

Cite this collection

Qiu, Bin; Xu, Daqian; Sun, Qiangsheng; Lin, Jin; Sun, Wei (2019): Manganese-Catalyzed Asymmetric Oxidation of Methylene

C–H of Spirocyclic Oxindoles and Dihydroquinolinones with Hydrogen

Peroxide. ACS Publications. Collection.