Investigations of the Reaction Mechanisms of 1,2-Indanediones
with Amino Acids
Posted on 2001-10-16 - 00:00
The reaction mechanisms of amino acids with a new class of fluorogenic reagents were investigated.
The structures of colored and fluorescent species formed in these reactions were partially confirmed
by experimental evidence. Reaction intermediates, C−N−C 1,3-dipoles derived from imines, were
trapped with dipolarophiles in 3 + 2 cycloadditions to form spiropyrrolidines.
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Petrovskaia, Olga; Taylor, Bruce M.; Hauze, Diane B.; Carroll, Patrick J.; Joullié, Madeleine M. (2016). Investigations of the Reaction Mechanisms of 1,2-Indanediones
with Amino Acids. ACS Publications. Collection. https://doi.org/10.1021/jo0105179