Fluevirosines A–C: A Biogenesis Inspired Example in the Discovery of New Bioactive Scaffolds from Flueggea virosa

Yue, Jian-Min

Fluevirosines A–C: A Biogenesis Inspired Example in the Discovery of New Bioactive Scaffolds from Flueggea virosa

Posted on 2016-02-20 - 02:38

Biogenesis inspired chemical investigation of a Chinese folk medicine, Flueggea virosa, returned three unprecedented C,C-linked trimeric Securinega alkaloids, fluevirosines A–C (1–3). Their absolute structures were characterized on the basis of spectroscopic data and computational analysis. Compounds 2 and 3 showed inhibition against the splicing of XBP1 mRNA.

CITE THIS COLLECTION

Zhang, Hua; Zhang, Chuan-Rui; Zhu, Kong-Kai; Gao, An-Hui; Luo, Cheng; Li, Jia; et al. (2016). Fluevirosines A–C: A Biogenesis Inspired Example in the Discovery of New Bioactive Scaffolds from Flueggea virosa. ACS Publications. Collection. https://doi.org/10.1021/ol303146a

https://doi.org/10.1021/ol303146a

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