Fabrication and Application of Levan–PVA Hydrogel
for Effective Influenza Virus Capture
Posted on 2020-06-16 - 16:04
To
prevent the transmission of pathogenic microorganisms such as
the influenza virus, efficient pathogen-capturing materials are required.
Here, we report a new pathogen-capturing and recovery material using
levan polysaccharide. We fabricated hydrogels by blending levan and
poly(vinyl alcohol) (PVA) and by using glutaraldehyde as a cross-linking
agent. Fabricated levan–PVA hydrogels have a high water solubility
and water adsorption ability. SEM observations showed that levan–PVA
hydrogels have a 3D porous structure. We confirmed by RT-PCR analysis
that the influenza virus capture efficiency of levan–PVA hydrogels
is higher than that of commercial cotton swabs. Moreover, we confirmed
that levan–PVA hydrogels on gauze as a filter material effectively
captured bioaerosol samples. Therefore, levan–PVA hydrogels
are expected to serve as simple and efficient pathogen capture and
recovery materials.
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Kim, Sun-Jung; Bae, Pan Kee; Choi, Mijin; Keem, Joo Oak; Chung, Wonseok; Shin, Yong-Beom (2020). Fabrication and Application of Levan–PVA Hydrogel
for Effective Influenza Virus Capture. ACS Publications. Collection. https://doi.org/10.1021/acsami.0c08333