Enantioselective Formal Synthesis of Palmerolide A

Pawar, Amit B.

Enantioselective Formal Synthesis of Palmerolide A

Posted on 2011-08-19 - 00:00

Enantioselective formal synthesis of macrolactone palmerolide A, a polyketide marine natural product, is described. Key strategies in the synthesis include the oxidative furan ring-opening of a chiral furyl carbinol for the installation of the 1,4-dienol core and a Jung nonaldol–aldol reaction for the dienamide core.

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Prasad, Kavirayani R.; Pawar, Amit B. (2016). Enantioselective Formal Synthesis of Palmerolide A. ACS Publications. Collection. https://doi.org/10.1021/ol201604c

https://doi.org/10.1021/ol201604c

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