Copper-Catalyzed Regioselective
sp3 C–H
Azidation of Alkyl Substituents of Indoles and Tetrahydrocarbazoles
Posted on 2019-09-11 - 14:46
An efficient regioselective sp3 C–H azidation
is developed using CuBr as the catalyst and Zhdankin azidoiodinane
as the “N3” source. Under simple and mild
reaction conditions, the azido group could be successfully incorporated
into the sp3 C–H alkyl substituents of indoles and
tetrahydrocarbazoles.
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Huang, Liwu; Xun, Xudong; Zhao, Man; Xue, Jianzhong; Li, Guofeng; Hong, Liang (2019). Copper-Catalyzed Regioselective
sp3 C–H
Azidation of Alkyl Substituents of Indoles and Tetrahydrocarbazoles. ACS Publications. Collection. https://doi.org/10.1021/acs.joc.9b01742
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AUTHORS (6)
LH
Liwu Huang
XX
Xudong Xun
MZ
Man Zhao
JX
Jianzhong Xue
GL
Guofeng Li
LH
Liang Hong