Catalyst- and Additive-Free Cascade Reaction of Isoquinoline N‑Oxides with Alkynones: An Approach to Benzoazepino[2,1‑a]isoquinoline Derivatives

Zhang, Zunting

Catalyst- and Additive-Free Cascade Reaction of Isoquinoline N‑Oxides with Alkynones: An Approach to Benzoazepino[2,1‑a]isoquinoline Derivatives

Posted on 2019-07-09 - 13:50

A cascade reaction of isoquinoline N-oxides with alkynones was developed, delivering a fluorescent benzoazepino[2,1-a]isoquinoline derivative. The reaction worked smoothly without requirement of any catalyst or additive, making this method economical and easy to handle.

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Li, Xuetong; Zhou, Guanghua; Du, Xinru; Wang, Tao; Zhang, Zunting (2019). Catalyst- and Additive-Free Cascade Reaction of Isoquinoline N‑Oxides with Alkynones: An Approach to Benzoazepino[2,1‑a]isoquinoline Derivatives. ACS Publications. Collection. https://doi.org/10.1021/acs.orglett.9b01966

https://doi.org/10.1021/acs.orglett.9b01966

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