Cascade Synthesis of (E)-2-Alkylidenecyclobutanols
Posted on 2009-10-15 - 00:00
A facile, one-pot reaction cascade condenses 1,1,1-trichloroalkanes with α,β-unsaturated ketones to unexpectedly furnish moderate to good yields of (E)-2-alkylidenecyclobutanols.
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Falck, J. R.; Bandyopadhyay, Anish; Puli, Narender; Kundu, Abhijit; Reddy, L. Manmohan; Barma, Deb K.; et al. (2016). Cascade Synthesis of (E)-2-Alkylidenecyclobutanols. ACS Publications. Collection. https://doi.org/10.1021/ol901985c