Asymmetric Transfer Hydrogenation of Heterobicyclic Alkenes with Water as Hydrogen Source

Published on 2019-02-12T14:50:13Z (GMT) by
The asymmetric transfer hydrogenation of heterobicyclic alkenes was accomplished by using water as the sole hydrogen source. The transformation was co-catalyzed by Pd­(OAc)<sub>2</sub>/Zn­(OTf)<sub>2</sub> dual catalyst with metallic zinc as reducing agent. Various azabenzonorbornadienes and oxabenzonorbornadienes were transformed to the corresponding chiral 1,2-dihydronaphthalenes by the asymmetric reductive ring-opening reactions with good to excellent enantioselectivities.

Cite this collection

Shen, Guoli; Chen, Jingchao; Xu, Dandan; Zhang, Xia; Zhou, Yongyun; Fan, Baomin (2019): Asymmetric Transfer Hydrogenation of Heterobicyclic

Alkenes with Water as Hydrogen Source. ACS Publications. Collection.