An Expeditious Approach to Tetrazoles from Amides
Utilizing Phosphorazidates

Matsugi, Masato

An Expeditious Approach to Tetrazoles from Amides Utilizing Phosphorazidates

Posted on 2020-07-07 - 21:43

A novel method was developed for the synthesis of tetrazoles from amides utilizing diphenyl phosphorazidate or bis(p-nitrophenyl) phosphorazidate as both the activator of amide–oxygen for elimination and azide source. Various amides were converted into the corresponding tetrazoles in good yields. This synthetic method allows to prepare 1,5-disubstituted and 5-substituted 1H-tetrazoles from various amides without the use of toxic or explosive reagents.

CITE THIS COLLECTION

DataCite

3 Biotech

3D Printing in Medicine

3D Research

3D-Printed Materials and Systems

4OR

AAPG Bulletin

AAPS Open

AAPS PharmSciTech

Abhandlungen aus dem Mathematischen Seminar der Universität Hamburg

ABI Technik (German)

Academic Medicine

Academic Pediatrics

Academic Psychiatry

Academic Questions

Academy of Management Discoveries

Academy of Management Journal

Academy of Management Learning and Education

Academy of Management Perspectives

Academy of Management Proceedings

Academy of Management Review

Ishihara, Kotaro; Shioiri, Takayuki; Matsugi, Masato (2020). An Expeditious Approach to Tetrazoles from Amides Utilizing Phosphorazidates. ACS Publications. Collection. https://doi.org/10.1021/acs.orglett.0c01890

https://doi.org/10.1021/acs.orglett.0c01890

or

Select your citation style and then place your mouse over the citation text to select it.