Thermal-/Light-Tunable Hydrogels Showing Reversible Widening and Closing Actuations Based on Predesigned Interpenetrated Networks
mediaposted on 2022-02-08, 22:30 authored by Chun-Yen Liu, Chien-Hsiang Chang, Thanh Tran Thi, Guan-Yi Wu, Chia-Ming Tu, Hung-Yi Chen
Poly(N-isopropylacrylamide) (PNIPAM) is a well-known biocompatible temperature-sensitive polymer. To enhance the biocompatibility of the artificial iris developed in our previous work, in this study, we demonstrate the syntheses of a series of cross-linked and interpenetrated poly(NIPAM-co-AM) hydrogel networks. Elasticities and mechanical properties of the synthesized hydrogels were investigated. Based on the results, the N3A1–N3A1 interpenetrated network (IPN) hydrogel was selected as a functional material for the fabrication of thermally tunable and light-tunable iris-like actuators. Fabrication of both gradient- and double-layer hydrogels was also carried out. Thermally responsive curling of the synthesized hydrogels was studied. Fabrication of thermal-/light-tunable IPN hydrogels showing actuation of widening and closing was achieved. The synthesized iris-like IPN hydrogels were further coated with polydopamine to promote light sensitivity. Both thermally sensitive actuation and light-sensitive actuation of widening and closing were demonstrated for the fabricated iris-like hydrogels. Stimulated variations in the inner diameter and the outer diameter surrounding the iris-like hydrogels were estimated. The results showed that poly(NIPAM-co-AM) IPN hydrogels are available for the design of thermal-/light-responsive actuators.
known biocompatible temperatureouter diameter surroundingthermal -/ lightpromote light sensitivitythermally responsive curlingartificial iris developedthermally sensitive actuationclosing actuations basedlike ipn hydrogelssensitive actuationthermally tunablelike hydrogelsresponsive actuatorsinner diametersensitive polymerlike actuatorssynthesized hydrogelslayer hydrogelsipn hydrogelstunable irissynthesized irisstimulated variationsprevious workn mechanical propertiesfunctional materialfabricated irisco also carried