ja3c06211_si_002.mp4 (1.17 MB)
Constructing Ultrastable Metallo-Cages via In Situ Deprotonation/Oxidation of Dynamic Supramolecular Assemblies
mediaposted on 2023-08-11, 19:03 authored by Pingru Su, Wenjing Zhang, Chenxing Guo, Hong Liu, Chuanhong Xiong, Runxu Tang, Chuanxin He, Zhi Chen, Xiujun Yu, Heng Wang, Xiaopeng Li
Coordination-driven self-assembly enables the spontaneous construction of metallo-supramolecules with high precision, facilitated by dynamic and reversible metal–ligand interactions. The dynamic nature of coordination, however, results in structural lability in many metallo-supramolecular assembly systems. Consequently, it remains a formidable challenge to achieve self-assembly reversibility and structural stability simultaneously in metallo-supramolecular systems. To tackle this issue, herein, we incorporate an acid-/base-responsive tridentate ligand into multitopic building blocks to precisely construct a series of metallo-supramolecular cages through coordination-driven self-assembly. These dynamic cagelike assemblies can be transformed to their static states through mild in situ deprotonation/oxidation, leading to ultrastable skeletons that can withstand high temperatures, metal ion chelators, and strong acid/base conditions. This in situ transformation provides a reliable and powerful approach to manipulate the kinetic features and stability of metallo-supramolecules and allows for modulation of encapsulation and release behaviors of metallo-cages when utilizing nanoscale quantum dots (QDs) as guest molecules.
responsive tridentate ligandmultitopic building blocksmetal ion chelatorswithstand high temperaturesdynamic cagelike assembliesacid -/ basestructural stability simultaneouslyconstructing ultrastable metallosupramolecular assembly systemssupramolecular systemsultrastable skeletonsstructural labilitystrong acidhigh precisionbase conditionstransformation providessupramolecular cagesstatic statesspontaneous constructionsitu release behaviorsprecisely constructpowerful approachmany metallokinetic featuresguest moleculesformidable challengedynamic naturedriven selfassembly reversibilityassembly enablesachieve self