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Biotemplated Nanopatterning of Planar Surfaces with Molecular Motors

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posted on 11.10.2006, 00:00 by Cordula Reuther, Lukasz Hajdo, Robert Tucker, Andrzej A. Kasprzak, Stefan Diez
We report on the generation of nanometer-wide, non-topographical patterns of proteins on planar surfaces. In particular, we used the regular lattice of reconstituted microtubules as template structures to specifically bind and transfer kinesin-1 and nonclaret disjunctional motor proteins. The generated tracks, which comprise dense and structurally oriented arrays of functional motor proteins, proved to be highly efficient for the guiding of microtubule transporters.