American Chemical Society
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t-Bu-QuinoxP* Ligand:  Applications in Asymmetric Pd-Catalyzed Allylic Substitution and Ru-Catalyzed Hydrogenation

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journal contribution
posted on 2007-09-14, 00:00 authored by Tsuneo Imamoto, Miwako Nishimura, Aya Koide, Kazuhiro Yoshida
The potential of the t-Bu-QuinoxP* ligand (1) as a chiral ligand in asymmetric synthesis was examined. The ligand exhibited good to excellent asymmetric induction in Pd-catalyzed asymmetric allylic substitution of 1,3-diphenyl-2-propenyl acetate (up to 98.7% ee) and in Ru-catalyzed asymmetric hydrogenation of ketones (up to 99.9% ee).