American Chemical Society
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syn Additions to 4α-Epoxypyranosides:  Synthesis of l-Idopyranosides

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journal contribution
posted on 2007-11-08, 00:00 authored by Gang Cheng, Renhua Fan, Jesús M. Hernández-Torres, Fabien P. Boulineau, Alexander Wei
The syn-selective addition of organozinc compounds to 4α-epoxypyranosides (4α-EPs), generated from methyl β-d-glucoside or aminoglucoside, provides an efficient route to pyranosides with α-l-ido configurations, including l-iduronic acid, neosamine B, and higher monosaccharide derivatives.