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Download filen‑Pentenyl-Type Glycosides for Catalytic Glycosylation and Their Application in Single-Catalyst One-Pot Oligosaccharide Assemblies
journal contribution
posted on 23.09.2019, 13:42 authored by Yujia Zu, Chenglin Cai, Jingyuan Sheng, Lili Cheng, Yingle Feng, Shengyong Zhang, Qi Zhang, Yonghai ChaiWe
have developed a new type of n-pentenyl-type
glycosides that can be activated by catalytic amounts of promoter,
Hg(NTf2)2 or PPh3AuCl/AgNTf2, at room temperature. The mild activation conditions and outstanding
stability of common protection/deprotection manipulations enable the
enynyl donors to have broad applications in constructing various glycosidic
bonds. Furthermore, under the Hg(NTf2)2-catalyzed
conditions, the sequential activation of different types of donors
was achieved, based on which a gentiotetrasaccharide was synthesized
via the newly developed single-catalyst one-pot strategy.
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Keywords
activation conditionsSingle-Catalyst One-Pot Oligosaccharide AssembliesPPhApplicationCatalytic GlycosylationGlycosideapplicationHggentiotetrasaccharideAuClsequential activationprotectionmanipulationpentenyl-type glycosidesstabilitysingle-catalyst one-pot strategypromoterroom temperatureglycosidic bondsenynyl donorsPentenyl-Type