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Reagent-Controlled Stereoselective Iodolactonizations

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journal contribution
posted on 20.12.2001, 00:00 authored by Jürgen Haas, Sandrine Piguel, Thomas Wirth
Iodocyclizations are important transformations and among stereocontrolled iodocyclizations mostly substrate-controlled versions using a chiral auxiliary have been successfully investigated. This work reports on stereoselective reagent-controlled iodolactonizations applying a new method using a combination of ICl and a primary amine leading to the highest selectivities known so far.

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