‘Upenamide:  An Unprecedented Macrocyclic Alkaloid from the
Indonesian Sponge Echinochalina sp.

Jiménez, Jorge I.; Goetz, Gilles; Mau, Christina M. S.; Yoshida, Wesley Y.; Scheuer, Paul J.; Williamson, R. Thomas; Kelly, Michelle

doi:10.1021/jo000789w.s001

jo000789w_si_001.pdf (342.73 kB)

‘Upenamide: An Unprecedented Macrocyclic Alkaloid from the Indonesian Sponge Echinochalina sp.

journal contribution

posted on 2000-11-17, 00:00 authored by Jorge I. Jiménez, Gilles Goetz, Christina M. S. Mau, Wesley Y. Yoshida, Paul J. Scheuer, R. Thomas Williamson, Michelle Kelly

‘Upenamide (1) represents a new class of macrocyclic marine alkaloid possessing both spirooxaquinolizidinone and hemiaminal ring systems. It was isolated from the Indonesian sponge Echinochalina sp. The gross structure of 1 was elucidated by spectroscopic methods and accurate mass measurements. A suggestion is made as to its biogenetic origin.