American Chemical Society
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‘Upenamide:  An Unprecedented Macrocyclic Alkaloid from the Indonesian Sponge Echinochalina sp.

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journal contribution
posted on 2000-11-17, 00:00 authored by Jorge I. Jiménez, Gilles Goetz, Christina M. S. Mau, Wesley Y. Yoshida, Paul J. Scheuer, R. Thomas Williamson, Michelle Kelly
‘Upenamide (1) represents a new class of macrocyclic marine alkaloid possessing both spirooxaquinolizidinone and hemiaminal ring systems. It was isolated from the Indonesian sponge Echinochalina sp. The gross structure of 1 was elucidated by spectroscopic methods and accurate mass measurements. A suggestion is made as to its biogenetic origin.