Visible-Light Photoredox/Nickel Dual Catalysis for the Cross-Coupling of Sulfinic Acid Salts with Aryl Iodides
journal contributionposted on 16.01.2018, 03:13 authored by Nai-Wei Liu, Kamil Hofman, André Herbert, Georg Manolikakes
An efficient cross-coupling of sodium or lithium sulfinates with aryl iodides, using a combination of nickel and photoredox catalysis, is described. The dual catalyst system enables a versatile synthesis of aryl sulfones at room temperature in good yields and displays a broad functional group compatibility. The potential utility of this method in the late-stage diversification of complex molecules and in the conversion of organolithium reagents and sulfur dioxide into sulfones is demonstrated.
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aryl sulfonesPhotoredoxlithium sulfinatescross-couplingaryl iodidesutilitysodiumCatalysiSulfinicmethodsynthesislate-stage diversificationcombinationmoleculeconversionCross-CouplingAryl Iodidescatalyst systemgroup compatibilitysulfur dioxideyieldorganolithium reagentsVisible-Lightroom temperaturephotoredox catalysisdisplay