posted on 2016-12-06, 00:00authored byYangyang Shen, Josep Cornella, Francisco Juliá-Hernández, Ruben Martin
A visible-light-mediated
atom transfer radical cyclization of unactivated
alkyl iodides is described. This protocol operates under mild conditions
and exhibits high chemoselectivity profile while avoiding parasitic
hydrogen atom transfer pathways. Preliminary mechanistic studies challenge
the perception that a canonical photoredox catalytic cycle is being
operative.