jo6b00973_si_001.pdf (2.21 MB)
Visible-Light-Initiated Na2‑Eosin Y Catalyzed Highly Regio- and Stereoselective Difunctionalization of Alkynes with Alkyl Bromides
journal contributionposted on 2016-06-15, 00:00 authored by Kuai Wang, Ling-Guo Meng, Lei Wang
A highly regioselective and stereoselective addition of alkyl bromides (amino-brominated aromatic β,β-dicyanoalkenes) to arylacetylenes by photoredox catalysis was developed. This difunctionalization of arylacetylenes was accomplished under ambient and metal-free conditions to produce alkenyl bromides in high efficiency with a wide range of group tolerance.