posted on 2023-11-10, 18:40authored byJinwei Yuan, Lu Shen, Na Guo, Yanli Yin, Pengyuan Yang, Liangru Yang, Yongmei Xiao, Shouren Zhang
An
effective method for accessing diverse difluoroalkylated
pyrrolo[1,2-a]indolediones via visible-light-induced
PhI(OAc)2-promoted cascade difluoroalkylation/cyclization
reaction under mild
conditions has been established. This method is noteworthy for its
use of DMSO–H2O as a green medium at room temperature
and avoidance of photocatalysts. The reactions are straightforward
to execute and convenient to expand on, provide good to excellent
yields, and have good functional group tolerance.