Virus-PEDOT Nanowires for Biosensing
journal contributionposted on 08.12.2010, 00:00 by Jessica A. Arter, David K. Taggart, Theresa M. McIntire, Reginald M. Penner, Gregory A. Weiss
The separate fields of conducting polymer-based electrochemical sensors and virus-based molecular recognition offer numerous advantages for biosensing. Grafting M13 bacteriophage into an array of poly (3,4-ethylenedioxythiophene) (PEDOT) nanowires generated hybrids of conducting polymers and viruses. The virus incorporation into the polymeric backbone of PEDOT occurs during electropolymerization via lithographically patterned nanowire electrodeposition. The resultant arrays of virus-PEDOT nanowires enable real-time, reagent-free electrochemical biosensing of analytes in physiologically relevant buffers.