posted on 2013-08-20, 00:00authored byJiaying Han, Feifei Han, Jin Ouyang, Quanmin Li, Na Na
In this article, a Venturi electrosonic
spray ionization (V-ESSI)
cataluminescence (CTL) sensor array was reported for discriminating
saccharides in solution. Integrating electrosonic spray ionization
(ESSI), a liquid system of Venturi self-pumping injection for the
CTL reaction, was fabricated for enhancing CTL reactivity of aqueous
samples. Comparing with simple Venturi injection by air and Venturi
easy ambient sonic-spray ionization without electric assistance (V-EASI),
the remarkable enhancement of CTL signals resulted from V-ESSI. This
system showed higher cross-reactive CTL responses catalyzed by alkaline
earth metal-nanomaterials than other catalysts, giving different signals
for a given saccharide on different catalysts and different responses
for different saccharides on the same catalyst. Then, a 4 × 2
CTL sensor array was used for obtaining “fingerprints”
of distinct CTL response patterns. Analyzed by linear discriminant
analysis (LDA), this V-ESSI CTL sensor array not only achieved the
well discrimination of different saccharides (99.9% of total variation)
but also discriminated four groups of urine sugar-level for urine
samples from diabetic patients (98.1% of discrimination accuracy).
It had good reproducibility and gave a linear range of 22.5–67558
μg/mL (R > 0.99) for xylose with a detection
limit of 7.4 μg/mL on MgO. As a new artificial tongue, this
system provided a simple, rapid, low cost, low energy consumption,
and environmentally friendly pathway for aqueous sample discrimination.
It has dramatically expanded applications of the CTL-based senor array
and will be applicable to clinical diagnoses, environment monitoring,
industrial controls, food industry, and various marine monitoring.