American Chemical Society
ol7b02736_si_001.pdf (2.58 MB)

Unified Approach to Substituted Allenoates via Pd-Catalyzed β‑Hydride Elimination of (E)‑Enol Triflates

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journal contribution
posted on 2017-09-27, 16:49 authored by Marie El Arba, Sara E. Dibrell, Ian T. Crouch, Doug E. Frantz
A robust synthesis of allenoates via a Pd-catalyzed β-hydride elimination of (E)-enol triflates is presented. Salient features of this method include low catalyst loadings, mild reaction conditions, and the ability to access all four patterns of substituted allenoates from a single substrate class.