Two New Quinochalcones from the Florets of <i>Carthamus tinctorius</i>

Two new quinochalcone compounds, named saffloquinoside A (<b>1</b>) and saffloquinoside B (<b>2</b>), were isolated from the florets of <i>Carthamus tinctorius</i>. Their unusual structures including their absolute stereochemistry were elucidated based on UV, IR, HRESIMS, 1D and 2D NMR data, and CD spectrum. Saffloquinoside A has an uncommon six−five member dioxaspirocycle and saffloquinoside B has a cyclohexatrione skeleton with a benzyl group and two <i>C</i>-glycosyl units. Saffloquinoside A exhibited middling anti-inflammatory activity.