American Chemical Society
ol2c01118_si_001.pdf (2.93 MB)

Tuning the Physicochemical Properties of BODIPY for Bioimaging via meso-Amino Acylation

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journal contribution
posted on 2022-05-04, 00:43 authored by Wei Shi, Jie Li, Xinyu He, Siming Zhou, Hongbao Sun, Haoxing Wu
A series of BODIPY probes with a wide emission range were prepared via aminoacylation at the meso-position. Functional moieties were also introduced to induce bathochromic shifts in emission, improve water solubility, increase Stokes shifts, and construct bioorthogonal turn-on probes. The developed analogues were successfully used in live-cell imaging, suggesting that the described strategy can be used to prepare probes with improved bioimaging potential.