ac402386m_si_001.pdf (276.06 kB)
Transmission Mode Desorption Electrospray Ionization (TM-DESI) for Simultaneous Analysis of Potential Inorganic and Organic Components of Radiological Dispersion Devices (RDDs)
journal contribution
posted on 2013-12-17, 00:00 authored by Kenyon M. Evans-Nguyen, Amanda Quinto, Tiffanie Hargraves, Hilary Brown, Jennifer Speer, David GlatterTransmission
mode desorption electrospray ionization (TM-DESI)
coupled to an ion trap mass spectrometer capable of source collision-induced
dissociation (CID) was used to completely analyze radiological dispersion
device components. Source CID significantly enhanced the signal for
metal ions by reducing adducts while eliminating chemical noise from
background molecules through extensive fragmentation. Source CID spectra
yielded reasonably accurate isotopic ratios for the metals studied.
By switching the source CID on and off between scans, all major constituents
in mixtures of simulated radionuclides and explosives were simultaneously
observed. These results indicate that TM-DESI/ion trap technology
could be a powerful on-site tool for nuclear forensics.